New Dual-Drug pump system shows promise for taming blood sugar spikes

NCT ID NCT06422325

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a new closed-loop system that automatically delivers both insulin and pramlintide to manage blood sugar in 33 adults with type 1 diabetes. Pramlintide slows digestion to prevent blood sugar spikes after meals. The system was compared to insulin alone. Researchers measured how well it controlled blood sugar after meals. This is an early step toward a more automated diabetes management system.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
pramlintide
What this could lead to
If successful, this approach could lead to better blood sugar control after meals for people with type 1 diabetes, reducing dangerous spikes.
What could go wrong
This is a small, early-stage study with only 33 participants. The system is complex and may not work for everyone. Pramlintide can cause nausea or low blood sugar.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

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