Stress hormone link to depression in diabetic children under the microscope

NCT ID NCT02377583

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates whether stress hormone activity is linked to depression and brain changes in children with type 1 diabetes. Researchers will measure cortisol levels and use brain scans in children aged 6–12 who have had diabetes for at least a year, comparing them to their healthy siblings. The goal is to understand how the body's stress system may contribute to mental health and brain differences in young people with diabetes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If links are found, this could point toward new ways to monitor or reduce mental health risks in children with type 1 diabetes.
What could go wrong
This is an observational study, not a treatment trial. It may find no clear connection, and results may not apply to all children with diabetes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Bordeaux Hôpital Pellegrin

    Bordeaux, Aquitaine, 33000, France

  • Service d'endocrinologie pédiatrique - Hôpital de la mère et de l'enfant - CHU de LIMOGES

    Limoges, Limousin, 87000, France

  • Service d'endocrinologie pédiatrique CHG Bayonne Centre Hospitalier de la Côte Basque

    Bayonne, Aquitaine, 64000, France

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