New insulin timing trick may tame blood sugar after pizza and burgers

NCT ID NCT05454891

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tested whether giving insulin as an extended bolus (over time) instead of all at once helps control blood sugar after high-fat, high-protein meals in teens with type 1 diabetes. Thirty teens using a closed-loop insulin pump ate a standardized breakfast and received either an extended or standard bolus on different mornings. The goal was to see if the extended bolus reduces prolonged high blood sugar or early low blood sugar.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of California San Francisco

    San Francisco, California, 94158, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

insulin (extended bolus via Tandem t:slim X2 insulin pump)

What this could lead to

If it works, this could give people with type 1 diabetes a better way to manage blood sugar after rich meals, reducing highs and lows.

What could go wrong

This is a small, early study in 30 teens, so results may not apply to everyone. The benefit may be small or not work for all meal types.

Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.