Can a simple insulin tweak prevent Exercise-Induced low blood sugar?

NCT ID NCT07550608

Completed Knowledge-focused Sponsor: Naama Constantini Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether cutting basal insulin by half before exercise helps keep blood sugar stable in people with type 1 diabetes. Eighteen active adults using insulin pumps completed two treadmill sessions—one with the insulin reduction and one without. Researchers measured blood sugar every 10 minutes to compare how men and women respond, aiming to reduce the risk of hypoglycemia during exercise.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 50% pre-exercise basal insulin rate reduction
What this could lead to: If successful, this could lead to better exercise guidelines for people with type 1 diabetes, helping them avoid dangerously low blood sugar during physical activity.
What could go wrong: This is a small, completed study with only 18 participants, so results may not apply to everyone. The intervention is specific to insulin pump users and may not work for others.

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Conditions

The condition(s) this trial relates to.

Motor Activity type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 1 DIABETES

Contacts and locations

Locations

Sylvan Adams Sport Institute, Tel Aviv University

Tel Aviv, Israel

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