New hope for diabetics with kidney transplants: islet cells may end insulin shots

NCT ID NCT01123187

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether transplanting insulin-making islet cells could help people with type 1 diabetes who already had a kidney transplant. Fourteen participants received up to three infusions of donor islet cells along with steroid-free immunosuppression. The goal was to see if they could stop taking insulin and keep their blood sugar under control one year later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

islet cell transplant

What this could lead to

If successful, this approach could help some people with type 1 diabetes who have had a kidney transplant achieve insulin independence and better blood sugar control.

What could go wrong

This is a small, early-phase study with only 14 participants, so results may not apply to everyone. The procedure and required immunosuppression carry risks like infection and bleeding.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypoglycemia type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital of Lille

    Lille, Nord, 59000, France