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Exercise in a Low-Oxygen chamber: a new way to manage diabetes?

NCT ID NCT06345612

Disease control Sponsor: Silesian Centre for Heart Diseases Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether eccentric training (a type of exercise that lengthens muscles) done in a low-oxygen (hypoxic) chamber or with creatine supplements could improve blood sugar control, muscle strength, and fitness in people with type 1 diabetes. 28 adults with type 1 diabetes for at least 10 years took part. The goal was to see if these approaches could help manage the disease better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
creatine supplementation
What this could lead to
If successful, this could point toward a way to improve blood sugar control and muscle strength in people with type 1 diabetes using exercise and supplements.
What could go wrong
This is a small, completed trial with only 28 participants, so results may not apply to everyone. The interventions are behavioral and dietary, not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

28 people

The number who actually took part.

Started

Nov 2023

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 45 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * type 1 diabetes of at least 10 years duration, * low physical activity, * BMI:20-31 kg/m2, * treated with multiple insulin injections (at least 4 daily) or insulin pump (continuous subcutaneous insulin infusion \[CSII\]), * negative ECG exercise test, * HbA1c ≤ 8,0%, * high knowledge about functional insulin therapy, carbohydrate counting and diabetes management during exercise, * experience in use of FreeStyleLibre2 (Flash Glucose Monitoring System, Abbott), * Informed consent to participate in research signed by enrolled subjects Exclusion Criteria: * HbA1c \> 8,0%, * advanced complications of diabetes \[pre-proliferative or proliferative retinopathy, and previous laser therapy, microalbuminuria or overt nephropathy, autonomic neuropathy (including lack of elevated heart rate during physical activity)\], * patients physically active (regular physical activities more than once a week), * positive ECG exercise test, * history of cardiovascular event or coronary heart disease

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Conditions

The condition(s) this trial relates to.

Hypoxia Motor Activity type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Type 1 diabetes

Contacts and locations

Locations

  • Department of Internal Diseases, Diabetology and Cardiometabolic Disorders, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Poland

    Zabrze, Silesian Voivodeship, 41-800, Poland

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