Baking soda may cut kidney risk in type 1 diabetes

NCT ID NCT02502071

Completed Disease control Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking two doses of sodium bicarbonate (baking soda) over 24 hours could reduce uric acid crystals in the urine of adults with type 1 diabetes. Uric acid crystals can harm the kidneys, so lowering them might help prevent diabetic kidney disease. The trial involved 45 adults aged 18-45 with type 1 diabetes and measured changes in urine uric acid levels and crystal formation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sodium bicarbonate
What this could lead to: If it works, this could point toward a simple way to reduce kidney stone or kidney disease risk in people with type 1 diabetes.
What could go wrong: This is a small, short-term study with only 45 participants, so results may not apply widely. Sodium bicarbonate can cause side effects like stomach upset or electrolyte imbalances.

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Conditions

The condition(s) this trial relates to.

diabetic kidney disease type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC KIDNEY DISEASE DIABETIC NEPHROPATHY TYPE 1 DIABETES

Contacts and locations

Locations

Barbara Davis Center for Diabetes

Aurora, Colorado, 80045, United States

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