Can an artificial pancreas help the Hardest-to-Control diabetes?

NCT ID NCT05282264

Completed Knowledge-focused Sponsor: Centre Hospitalier Sud Francilien Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at whether people with severe, long-term uncontrolled type 1 diabetes would accept and benefit from a closed-loop insulin delivery system (an 'artificial pancreas'). Researchers followed 66 adults with very high blood sugar levels over several years. The goal was to see how many kept using the system and whether it improved their blood sugar control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: closed-loop insulin delivery system
What this could lead to: If successful, this could show that closed-loop insulin systems are acceptable and helpful for people with very poorly controlled type 1 diabetes.
What could go wrong: This is a small, single-center observational study, not a randomized trial. Results may not apply to all patients, and the system may not work as well in real-world settings.

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Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 1 DIABETES

Contacts and locations

Locations

Centre Hospitalier Sud Francilien

Corbeil-Essonnes, 91106, France
Penfornis

Corbeil-Essonnes, Centre Hospitalier Sud Francilien, 91106, France

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