Prozac may reduce Exercise-Related low blood sugar in type 1 diabetes
NCT ID NCT01672255
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early study tests whether the antidepressant fluoxetine (Prozac) can improve the body's nervous system response during exercise in people with type 1 diabetes. Many with diabetes avoid exercise due to fear of low blood sugar. The study includes 64 adults—half with type 1 diabetes and half healthy—who take either Prozac or a placebo for 6 weeks. Researchers measure stress hormone levels during exercise to see if Prozac helps the body respond better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fluoxetine (Prozac)
- What this could lead to
- If successful, this could point toward a way to help people with type 1 diabetes exercise more safely by reducing their risk of low blood sugar.
- What could go wrong
- This is a very early, small study with only 64 participants. It tests a theory, not a proven treatment, and results may not lead to any practical change.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Maryland, Baltimore
Baltimore, Maryland, 21201, United States
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