Prozac may reduce Exercise-Related low blood sugar in type 1 diabetes
NCT ID NCT01672255
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This early study tests whether the antidepressant fluoxetine (Prozac) can improve the body's nervous system response during exercise in people with type 1 diabetes. Many with diabetes avoid exercise due to fear of low blood sugar. The study includes 64 adults—half with type 1 diabetes and half healthy—who take either Prozac or a placebo for 6 weeks. Researchers measure stress hormone levels during exercise to see if Prozac helps the body respond better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fluoxetine (Prozac)
What this could lead to
If successful, this could point toward a way to help people with type 1 diabetes exercise more safely by reducing their risk of low blood sugar.
What could go wrong
This is a very early, small study with only 64 participants. It tests a theory, not a proven treatment, and results may not lead to any practical change.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Maryland, Baltimore
Baltimore, Maryland, 21201, United States