Weekly shot shows promise for blood sugar and weight control in type 1 diabetes

NCT ID NCT05537233

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 28 times

Summary

This study tested a once-weekly injection of semaglutide in 115 adults with type 1 diabetes and obesity who were already using an automated insulin pump system. The goal was to see if the drug could help them achieve better blood sugar control (more time in target range) and lose at least 5% of their body weight. Participants were followed for 26 weeks, and results were compared to a placebo group.

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Contacts and locations

Locations

  • Barbara Davis Center for Diabetes

    Aurora, Colorado, 80045, United States

  • Harold Schnitzer Diabetes Health Center

    Portland, Oregon, 97239, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Iowa Diabetes Research Center

    West Des Moines, Iowa, 50265, United States

Conditions

Explore the condition pages connected to this study.