Transplant study digs into gut chemistry to uncover blood sugar mysteries
NCT ID NCT02234349
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how pancreas-kidney transplantation changes bile acids and gut-related metabolism in people with type 1 diabetes and kidney disease. Researchers will measure bile acid levels and glucose responses in 50 transplant patients, comparing them to kidney-only transplant patients and healthy controls. The goal is to understand why some patients still have abnormal blood sugar after transplantation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pancreas-kidney transplantation
- What this could lead to
- If successful, this could help doctors understand why some transplant patients still have blood sugar problems, possibly leading to better treatments.
- What could go wrong
- This is a small, early pilot study with only 50 participants. It is designed to observe changes, not to test a new treatment, so it may not lead to direct patient benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC KIDNEY DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hôpital Edourad Herriot - Pavillon P
Lyon, 69437, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Aging kidneys under the microscope: could a simple test predict failure?
- Can an app and cash rewards tame type 1 diabetes in young adults?
- Could your gut bacteria hold the key to protecting your kidneys?
- Food as medicine: could cooking classes slow kidney disease?
- Smart insulin pump aims to end dangerous nighttime blood sugar swings
- Could a phone app be the key to managing kidney disease?