INFLAMMATION

This study looked at whether tiny plastic particles (microplastics) we encounter daily can contribute to obesity and gut problems. Researchers gave 96 overweight adults a probiotic supplement or a placebo to see if it could reduce the harmful effects of microplastics. The goal wa…

This study tested a drug called ziltivekimab in 36 adults with advanced chronic kidney disease and high inflammation. The goal was to see if it could safely reduce inflammation and lower heart disease risks. Participants received either a low dose, a high dose, or a placebo injec…

This study looked at whether taking probiotics alongside usual diabetes medications can improve blood sugar, cholesterol, and inflammation in adults with type 2 diabetes. 77 participants aged 35-65 took probiotics or a placebo. The goal was to see if changing gut bacteria could h…

This study tested a protein called GcMAF in 120 adults with chronic inflammatory diseases like rheumatoid arthritis that didn't respond to standard treatments. The goal was to see if it is safe and can reduce inflammation. The study had two parts: first to find the right dose, th…

This study tested whether colchicine, an anti-inflammatory drug, can slow the buildup of calcium in the aortic valve in people with mild-to-moderate aortic stenosis. 24 adults were randomly assigned to take colchicine or a placebo for 6 months. The main goal was to see if the dru…

This study looked at whether taking a Cistanche deserticola extract along with aerobic exercise for 18 weeks can improve body composition, insulin resistance, and inflammation in men with central obesity (excess belly fat). 125 Chinese men aged 50-55 with a large waist and high B…

This study tested a device that filters the blood during complex heart surgery to remove inflammatory substances. Forty-one adults having high-risk heart procedures were enrolled. The goal was to see if the filter could reduce organ failure and improve recovery after surgery.

This study tested whether eating Greek yogurt for 8 weeks could improve bone health and reduce inflammation in adults aged 55 and older. Some participants also took exercise classes. Researchers measured blood markers of bone turnover and inflammation to see if yogurt made a diff…

This study looked at whether a 24-week exercise program can improve physical fitness, muscle strength, and overall health in people who received a kidney transplant. 345 participants were assigned to either an exercise group or routine care. The goal was to see if exercise could …

This study looked at whether garlic supplements can improve blood vessel health and reduce inflammation in adults with chronic kidney disease who are on hemodialysis. 58 patients took part. Researchers measured markers like endocan and IL-6 to see if garlic helped. The goal was t…

This study looked at whether taking fish oil supplements while exercising can lower inflammation linked to obesity. Overweight adults with high triglycerides and prediabetes took fish oil and followed an exercise program for several weeks. Researchers measured changes in blood ma…

This study tested whether colchicine, a common anti-inflammatory medicine, could improve metabolism in people with obesity who have high inflammation and high insulin levels but not yet high blood sugar. About 152 adults and teens took colchicine or a placebo daily for 12 weeks. …

This study looked at whether colchicine, a drug used for gout, can reduce inflammation in the arteries of people with diabetes or pre-diabetes who recently had a heart attack or stroke. Inflammation is a key driver of artery plaque buildup, which can lead to more heart problems. …

This study looked at whether eating micro-vegetables (young seedlings of larger veggies) for 6 weeks can lower inflammation in adults aged 60 and older with a BMI over 25. Researchers measured changes in blood markers, muscle and fat tissue, thinking, and mouth/gut bacteria. The …

This study looked at whether eating more dairy products for 6 weeks could lower inflammation and other markers of heart disease in overweight adults. Researchers measured these markers both when participants had fasted and after a high-fat meal. The study involved 32 adults who w…

This study tested three doses of a monthly injection called Ziltivekimab in 264 adults with advanced chronic kidney disease and high inflammation. The goal was to see which dose best lowers inflammation markers, like hs-CRP, to help plan a larger trial on heart risks. Participant…

This study looked at whether green tea extract can improve gut health and lower inflammation in people with metabolic syndrome and in healthy adults. 46 participants took either green tea extract or a placebo for one month, then switched to the other for another month. The resear…

This study looked at whether eating a whole-food, plant-based diet for 8 weeks could reduce markers of cancer and inflammation in 121 active firefighters. Participants either followed the plant-based diet or their usual diet. The goal was to see if diet changes could improve heal…

This study looked at whether two simple tests—a breath test (FeNO) and a blood test—can help diagnose asthma more easily than current hospital-based breathing tests. Researchers studied 123 people with suspected asthma to see if these tests could accurately identify the disease a…

This study looked at whether omega-3 fatty acids can reduce inflammation and improve mood in people with treatment-resistant depression. 14 adults who were still depressed despite taking antidepressants were randomly given either omega-3 or a placebo for 12 weeks. Researchers mea…

This study looked at whether taking powdered tart cherries helps trained men and women recover from repeated sprints. Forty healthy, active adults did intense sprinting exercises and then took either tart cherry powder or a placebo. Researchers measured muscle soreness, power, in…

This study looked at whether drinking Montmorency tart cherry juice can improve sleep and lower inflammation in adults who have trouble sleeping. Thirty-four participants with sleep issues and a higher body mass index took part. Researchers measured sleep time, sleep quality, and…

This study tested whether a combination of UC-II, glucosamine, and curcumin supplements can reduce knee pain and inflammation in 32 adults with chronic knee pain. Participants took the supplements or a placebo for a period, and researchers measured pain levels, knee function, and…

This study tested a 12-week program called the Integrated Stress Toolbox for Healthcare Providers (ISTH) to see if it helps Mexican healthcare workers feel less stressed and burned out. Over 2,300 participants were randomly assigned to either the toolbox training or a waitlist. T…

This study looked at whether applying cold packs to sore muscles after exercise can reduce pain, swelling, and inflammation. 48 healthy adults aged 18-30 did exercise to cause muscle soreness, then used a cold pack or no treatment. Researchers measured pain, swelling, and blood m…

This study looked at whether listening to music can lower stress and inflammation in sedated adults on breathing machines in the intensive care unit (ICU). Researchers measured stress hormones and inflammation markers in the blood before and after a 60-minute music session or sta…

This study tested two types of cold therapy (cryotherapy) to reduce pain and inflammation after root canal treatment in 30 adults with infected lower premolars. One group used an ice pack on the cheek for 30 minutes, another had a cold saline rinse inside the tooth, and a control…

This study tested a 6-week online sleep program for 40 people who recently lost a spouse or long-term partner. The program used cognitive behavioral therapy for insomnia (CBT-I) to help improve sleep and reduce inflammation. Participants wore a watch to track sleep and gave blood…

This study tested whether using an ultrasonic surgical device (piezosurgery) instead of a traditional rotary drill reduces pain, swelling, and jaw stiffness after removing impacted wisdom teeth. Twenty-two healthy adults each had one tooth removed with the ultrasonic tool and the…

This study tested whether a natural probiotic (Lactobacillus rhamnosus GG) could reduce inflammation and improve PTSD symptoms in veterans. 383 veterans with PTSD and a bowel disorder took part. Researchers measured blood markers of inflammation, gut health, and PTSD symptoms to …

This pilot study tested whether taking ETAS® daily for 12 weeks could improve thinking, mood, and inflammation in healthy adults aged 60 to 80 who had mild memory complaints. Researchers measured cognitive function and blood markers of inflammation. The goal was to see if this su…

This study looked at whether a single injection of Dexycu (9% dexamethasone) can safely clear inflammation in the eye after cataract surgery. It included 263 adults over 40 who had cataract surgery. The main goal was to see how many people had no signs of inflammation 8 days afte…

This study tested whether a green tea extract called EGCG is safe and practical for older adults (65+) who have survived cancer and are frail or pre-frail. Twenty-four participants took either the supplement or a placebo for 12 weeks. The main goal was to see if people would join…

This study tested whether a fermented milk drink containing a specific probiotic (Lactobacillus casei Shirota) could help elderly Taiwanese people with sarcopenia, a condition of age-related muscle loss. Researchers measured changes in gut bacteria, muscle strength, and walking s…

This study compared how full-fat and fat-free milk and yogurt affect the bacteria in your gut and your risk for heart disease. Researchers gave 37 adults over 50 different dairy products and measured changes in gut microbes and heart-related markers. The goal was to see if fat co…

This study looked at how eating a high-fat diet for 5 days affects inflammation in older adults (ages 50-79) with normal weight or obesity. Researchers measured blood markers and gut bacteria to see differences between the two groups. The goal was to understand how body weight ch…

This study tested avenanthramide, a natural compound found only in oats, to see if it is safe for people. Researchers gave single and multiple doses to 92 healthy volunteers and people with a larger waistline and low-grade inflammation. The main goal was to check for side effects…

This study tested whether drinking dairy products after exercise helps bone health and reduces inflammation better than a sugary drink or water. Twenty healthy young adults took part. Researchers measured bone activity and inflammation markers in the blood.

This study looked at how the bodies of 30 young, elite rowers change during intense exercise. Researchers measured hormones, metabolism, and iron levels before and after a 2000-meter rowing test. The goal was to better understand how athletes adapt to hard physical strain.

This study tested whether a blood protein called PTX3 can predict how much weight people lose and how their metabolism improves after gastric bypass surgery. Researchers followed 23 adults with obesity for 6 months after surgery. The goal was to see if PTX3 levels before surgery …

This study tested whether a daily capsule of polysaccharide peptide (PsP) from the reishi mushroom could lower markers of oxidative stress and inflammation in 200 adults who smoke or are around smoke. Participants took either PsP or a placebo for 8 weeks, and researchers measured…

This study collected blood samples from 310 HIV-infected adults and healthy volunteers to measure markers of inflammation, blood clotting, and blood vessel function. The goal was to better understand how these markers relate to HIV and risks like heart disease or stroke. No treat…

This study tested a new experimental drug called MMV367 in 12 healthy adults who were intentionally infected with the malaria parasite. The goal was to see how the drug works in the body and how well it clears the parasite. Participants were closely monitored and given standard m…

This study followed 300 people with hand osteoarthritis for up to 8 years. Researchers used exams, imaging, and surveys to track pain, inflammation, and joint changes. The goal was to learn how the disease progresses and what factors predict outcomes, not to test a new treatment.

This study looked at whether a fermented soy powder called Q CAN PLUS could improve thinking, immune function, and the body's response to the flu vaccine in healthy adults aged 65 and older. Researchers measured changes in blood markers and cognitive tests over 16 weeks. The goal…

This pilot study tested whether a daily NAD+ supplement can improve thinking skills and reduce inflammation in healthy women aged 40 to 80. Over 4 weeks, 53 participants took either NAD+ or a placebo and completed computer-based thinking tests and blood draws. The goal was to see…

This study explored how diet influences inflammation in 393 healthy and obese adults. Researchers measured immune cells, hormones, and metabolism after a high-fat meal to understand the link between eating habits and chronic disease risk. The goal was to gather knowledge, not to …

This study looked at 140 intensive care unit (ICU) healthcare workers to see if burnout and stress are linked to signs of inflammation in the blood. Participants completed surveys about their mental well-being and gave blood samples to measure inflammatory markers. The goal was t…

This study looked at whether eating blueberries can improve immune function in overweight older men and postmenopausal women aged 50-70. Researchers measured changes in immune cells and inflammation markers in 52 participants. The goal was to understand how a simple dietary chang…

This study looked at 50 people with inflammatory bowel disease (IBD) to understand how their diet, meal patterns, and nutrition relate to their quality of life, gut symptoms, and mood. Researchers used food recall interviews and questionnaires to gather information. The goal was …

This study tested a new, low-cost infection score called ICIS in 97 adult and child burn patients. The goal was to see if ICIS could better tell the difference between inflammation caused by infection versus other causes, compared to standard blood markers. The results may help d…

This study looked at 120 male blood donors to see if donating plasma more often affects their health. Some donated plasma every 2 weeks, some donated 3 times every 2 weeks, and some donated whole blood every 3 months. Researchers measured protein levels, inflammation markers, and…

This study looked at how small differences in certain genes affect the way blood cells respond to environmental exposures. Researchers collected blood samples from 178 healthy adults aged 18 to 45 to measure gene activity and protein binding. The goal was to better understand why…

This study looked at whether adding fiber (inulin) to a low-fiber diet could increase helpful gut bacteria and improve the body's immune response to a typhoid vaccine. Sixty healthy adults with low fiber intake took part. Researchers measured changes in gut health, inflammation, …

This study looked at whether taking a daily supplement called PQQ for six weeks changes how the body uses fat and energy during exercise in people who are not endurance-trained. Twenty-four basketball players took either PQQ or a placebo. Researchers measured their body compositi…

This study looked at whether inflammation is linked to heart disease and diabetes. Researchers compared 150 adults with these conditions to healthy volunteers using blood tests, heart scans, and tissue samples. The goal was to better understand the relationship, not to test a new…

This small early-phase study looked at how a class of diabetes drugs called SGLT2 inhibitors might reduce inflammation linked to heart and kidney disease. Six healthy adults took the medication for three days, and researchers measured changes in inflammation markers. The goal was…

This study looked at 60 people to see if gum disease (periodontitis) and Parkinson's disease share a biological connection through inflammation. Researchers measured certain substances in saliva and blood related to tryptophan, a natural amino acid. They found higher levels of so…

This study looked at how different levels of processing in plant-based protein foods (like veggie burgers or protein powders) affect the bacteria in your gut and your body's metabolism. Thirty-eight healthy adults took part. The goal was to understand, not to treat any disease.

This study looked at 130 people with lumbar disc herniations (slipped discs) to see if a blood-based immune index could predict which discs would shrink on their own. Researchers calculated the Systemic Immune-Inflammatory Index from routine blood counts. The goal was to better u…

This study tested a plant-based supplement (LLP-01) in 32 healthy adults aged 50-75 to see if it changed blood markers related to inflammation and heart health. Participants took the supplement or a placebo for 2 months. The goal was to gather information, not to treat any diseas…

This study explored whether emotional distress before treatment and certain blood markers (like inflammation levels) can predict how well immunotherapy works in people with advanced lung or gastroesophageal cancer. Researchers followed 196 patients who had not received prior trea…

This study looked at nearly 1,000 adults aged 30-60 to compare levels of harmful chemicals, oxidative stress, and inflammation in long-term users of a tobacco heating system versus cigarette smokers and those who quit. Participants were grouped based on their smoking or vaping hi…

This study looked at how legal cannabis use changes alcohol drinking habits, gut bacteria, and brain function in 77 adults who regularly use both alcohol and cannabis. Participants tracked their drinking and cravings over a month, gave blood and stool samples, and completed think…

This study looked at medical records of 380 men to see if a score called Modified EASIX, calculated from routine blood tests, can help predict how severe erectile dysfunction (ED) is. Researchers compared the scores of men with and without ED. No treatments or extra tests were gi…

This study looked at 155 adults who had weight-loss surgery to see if using a lower flow of anesthesia gas (sevoflurane) affected inflammation levels differently than a standard flow. Researchers checked blood markers of inflammation before and after surgery. The goal was to lear…

This study looked at whether eating almonds every day can strengthen the immune system and improve how well the flu vaccine works in overweight middle-aged men and women. About 61 participants ate almonds or a placebo for several months. Researchers measured immune cells and infl…

This study looked at how three different types of dietary fats affect inflammation, blood fats, blood sugar, and gut bacteria in 25 healthy adults aged 18-60. Participants ate a special diet to see which fat source caused the least inflammation and best heart health markers. The …

This study looked at how psoriasis, a skin condition caused by inflammation, might be linked to heart disease and other metabolic problems. Researchers followed 386 adults with psoriasis for up to 4 years, using blood tests, heart scans, and imaging to measure inflammation in blo…

This study looked at how inflammation changes the brain's reward system in older adults (ages 60-80) with anxiety. Researchers used brain scans and computer tasks to measure loss of pleasure and motivation after an inflammatory challenge. The goal was to understand the link betwe…

This study looked at how CrossFit and traditional weight training affect inflammation and oxidative stress in people who don't usually exercise. Twenty-four healthy, untrained adults followed a 12-week program, doing five sessions per week. Researchers measured blood markers befo…

This study looked at how age and body fat affect inflammation in 100 veterans. Researchers wanted to see if losing a moderate amount of weight and increasing aerobic exercise could lower inflammation. The goal was to understand the link between body fat, aging, and health risks l…

This study looked back at the records of 266 hospitalized adults who had a special PET scan (FDG-PET/CT) to find the cause of an unexplained fever or inflammation. The goal was to see how often the scan helped doctors make a diagnosis and whether it changed treatment plans. The r…

This study looked at whether avoiding plastic in food, personal care, and cleaning products can lower levels of plastic-related chemicals in the body and improve health markers. Sixty adults with heart disease risk factors either followed a low-plastic routine for 4 weeks or cont…

This study looked at whether taking a mix of natural plant compounds (polyphenols) could help protect the body from everyday environmental pollutants. Researchers gave 98 healthy adults either polyphenol supplements or a placebo for a period of time. They measured changes in gut …