Could a protein derived from vitamin d tame chronic inflammation?
NCT ID NCT06877364
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a protein called GcMAF, which is made from vitamin D-binding protein and is thought to calm the immune system. Researchers gave it to 120 adults with chronic inflammatory conditions like rheumatoid arthritis or cystitis that didn't improve with standard treatments. The goal was to check if it's safe and if it can reduce inflammation, measured by blood markers and disease activity scores.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- GcMAF (a protein derived from vitamin D-binding protein that activates immune cells)
- What this could lead to
- If successful, this could point toward a new treatment option for people with chronic inflammatory diseases who haven't responded to standard therapies.
- What could go wrong
- This is an early-phase trial (Phase 1/2) with a small number of participants, so results may not confirm effectiveness or safety in larger populations. The treatment is experimental and may cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC CYSTITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Center For New Medical Technologies
Novosibirsk, Russia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a gentle yoga practice turn down the Body's pain and inflammation?
- Could a stress hormone be behind the hidden danger of low blood sugar?
- Grape powder may help aging immune systems — a trial puts it to the test
- Can a new shoulder implant restore Pain-Free movement?
- Can a less invasive hip surgery speed up recovery?
- Which hip implant lasts longer? a Head-to-Head trial aims to find out