Heated tobacco vs cigarettes: which is less harmful?

NCT ID NCT05385055

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether people who used a tobacco heating system for at least 2 years had lower levels of harmful chemicals, cell stress, and inflammation in their bodies compared to cigarette smokers. About 974 healthy adults aged 30-60 from Asia and Europe took part. The goal was to measure differences in blood and urine markers, not to treat or cure any disease.

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Conditions

The condition(s) this trial relates to.

Inflammation inflammatory disease Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aristotle University Thessaloniki/Papageorgiou Hospital

    Thessaloniki, 56403, Greece

  • Bioresearch Group

    Nadarzyn, 05-830, Poland

  • Centrum Medyczne Pratia

    Katowice, 40-081, Poland

  • Centrum für Diagnostik und Gesundheit, Klinische Forschung und Entwicklung

    München, Germany

  • Clinical Medical Research Sp. z o.o.

    Katowice, 40-156, Poland

  • Clintrial s.r.o.

    Prague, Czechia

  • Hakata Clinic

    Fukuoka, Japan

  • Klinische Forschung Dresden GmbH

    Sachsen, 1069, Germany

  • Klinische Forschung Hamburg GmbH

    Hamburg, 20253, Germany

  • Klinische Forschung Hannover-Mitte GmbH

    Hanover, 30159, Germany

  • Klinische Forschung Karlsruhe GmbH

    Karlsruhe, 76137, Germany

  • Medical Center ReSpiro

    Razgrad, 7200, Bulgaria

  • Medical Center Zara-Med EOOD

    Stara Zagora, 6000, Bulgaria

  • Medical Centre Asklepii

    Kyustendil, 2600, Bulgaria

  • Medical Centre Leo Clinic EOOD

    Lovech, 5500, Bulgaria

  • National and Kapodistrian University of Athens, Medical school, Attikon Hospital, 2nd Cardiology Department

    Athens, Greece

  • Nishikumamoto Hospital

    Minami, Japan

  • OCROM Clinic

    Osaka, 6560853, Japan

  • OPHAC Hospital

    Osaka, 5320003, Japan

  • Ordinance praktickeho lekai'e

    Přeštice, 33401, Czechia

  • Praglandia s.r.o.

    Prague, 15000, Czechia

  • Praxis Reinfeld Mitte

    Reinfeld, Germany

  • PreventaMed s.r.o.

    Olomouc, 77900, Czechia

  • Private Internal ambulance

    Karlovy Vary, 360 17, Czechia

  • Samoncho Clinic

    Tokyo, 1600017, Japan

  • Schaum/Hecht_RED Institut fur medizinische Forschung und Fortbildung GmbH

    Oldenburg in Holstein, 23758, Germany

  • Sumida Hospital

    Tokyo, Japan

  • Synexus Clinical Research GmbH

    Frankfurt, 60313, Germany

  • Synexus Polska Sp zoo OddziaL w Lodzi

    Lodz, 90-127, Poland

  • ToCROM Clinic

    Tokyo, 160-0008, Japan

  • Tomed Tomasz Miszalski-Jamka

    Krakow, 31-353, Poland

  • Velocity Clinical Research Germany GmbH

    Berlin, 10787, Germany

  • Velocity Clinical Research Leipzig

    Leipzig, 4103, Germany

  • Vestra Clinics s.r.o.

    Rychnov nad Kněžnou, Czechia

  • Yokohama Minoru Clinic

    Kanagawa, 2320064, Japan

  • Zdravi - fit, s.r.o.

    Protivín, 398 11, Czechia

  • emovis GmbH

    Berlin, Germany