INFLAMMATION

This study tests whether a newer type of dialysis filter (medium cut-off membrane) can reduce inflammation and improve heart function better than the standard filter in people with end-stage kidney disease. Thirty adults on maintenance hemodialysis will use each filter for three …

This study looks at whether icosapent ethyl, a purified fish oil medication, can reduce inflammation and improve heart structure in people with coronary artery disease. Researchers will follow 420 patients for one year, comparing those who receive standard care plus icosapent eth…

This study tests a drug called 2-HOBA in 20 adults with salt-sensitive high blood pressure. The drug aims to calm overactive immune cells that may worsen blood pressure when salt is eaten. Researchers will measure blood pressure changes and blood vessel health after taking 2-HOBA…

This study will test whether taking ginger supplements for two months can lower inflammation and oxidative stress in people with coronary artery disease. Fifty adults with confirmed heart disease will be randomly assigned to receive either ginger extract or a placebo. Researchers…

This study looks at whether taking royal jelly and propolis (natural bee products) for two months can lower inflammation and improve heart health in 50 adults with coronary artery disease. Participants will be randomly assigned to receive the supplements or a placebo, and researc…

This phase 2 trial tests whether disulfiram, a drug already approved for alcohol use disorder, can safely reduce joint inflammation in people with rheumatoid arthritis who are overweight. Twenty adults with active arthritis despite standard treatment will take either disulfiram o…

This study will test whether a natural fiber called oligofructose, found in foods like onions and bananas, can help improve blood sugar, cholesterol, and inflammation in Saudi adults with type 2 diabetes. A total of 100 people (50 with diabetes and 50 without) will take either th…

This study tests whether a daily synbiotic supplement (probiotics plus prebiotics) can lower inflammation and improve digestive symptoms in adults with chronic kidney disease stages 3 to 5 who are not yet on dialysis. One hundred participants will receive either the supplement or…

This study tests a specially designed plant-based drink for adults aged 60 to 80. The drink contains vitamin D, zinc, and other nutrients meant to strengthen the immune system and reduce inflammation. Researchers will compare it to a plain plant-based drink over several weeks to …

This study tests whether Anakinra, a drug that reduces inflammation, can prevent dangerous drops in blood sugar after meals in a patient who had his stomach removed. The 52-year-old man also has kidney failure and needs dialysis. Over 10 weeks, he will receive either Anakinra or …

This study tests if giving a short course of steroids (methylprednisolone) for 7 days can help adults with heart failure who are in cardiogenic shock, a serious condition where the heart can't pump enough blood. The goal is to reduce harmful inflammation and help patients recover…

This study tests whether a multi-strain postbiotic supplement taken daily for 28 days can reduce inflammation, improve gut symptoms, and aid recovery after exercise in healthy adults. About 50 physically active men and women aged 18 to 55 will be randomly assigned to receive eith…

This study looks at how aging changes tiny parts of our cells called mitochondria, which produce energy. Researchers will take small skin samples and blood from 90 healthy adults aged 18-90 to measure inflammation and cell aging markers. The goal is to better understand why we ag…

This study tests whether a Mediterranean diet can improve gut health, body composition, and inflammation in toddlers aged 2-3. Forty families will be randomly assigned to either a 3-week Mediterranean diet with free food boxes and nutrition education, or their usual diet. Researc…

This study will follow 5,000 adults with immune system problems to see if certain blood cell mutations (called clonal hematopoiesis) are linked to their condition. Researchers will track new cases of immune-related diseases over time. No treatments or drugs are tested—this is pur…

This study tests a special filter (Jafron HA-60) used during heart-lung bypass in 20 children having open-heart surgery. The filter is designed to remove inflammatory substances from the blood, which may help reduce complications. The main goal is to see if using the filter is sa…

This study looks at whether inflammation linked to aging affects how much anesthesia older adults need during major abdominal surgery. Researchers will compare younger (18-30) and older (60+) patients by monitoring brain activity, blood markers, and tissue samples. The goal is to…