New drug targets immune system to fight Salt-Sensitive hypertension

NCT ID NCT07602166

Not yet recruiting Disease control Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study tests a drug called 2-HOBA in 20 adults with salt-sensitive high blood pressure. The drug aims to calm overactive immune cells that may worsen blood pressure when salt is eaten. Researchers will measure blood pressure changes and blood vessel health after taking 2-HOBA or a placebo.

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Conditions

The condition(s) this trial relates to.

essential hypertension, genetic hypertensive disorder Inflammation inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIGH BLOOD PRESSURE INFLAMMATION RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM SALT SENSITIVITY OF BLOOD PRESSURE

Contacts and locations

Locations

Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

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