A simple blood pressure cuff trick could shield the heart in kidney disease

This trial tests whether repeated, brief periods of reduced blood flow to the leg—created by inflating a blood pressure cuff—can improve blood pressure, heart rate, and markers of inflammation in people with chronic kidney disease. The procedure, called ischemic preconditioning, is thought to trigger the body's own protective mechanisms against future injury. Over three days, participants will undergo four 5-minute cycles of cuff inflation and deflation, with blood and vital signs measured before and after. The goal is to see if this simple, non-drug intervention can offer cardiovascular benefits in this high-risk population.