HEMODIALYSIS

This study tests a medication called AV-001 to see if it can protect the brain in people who undergo regular dialysis. Many dialysis patients experience memory problems or mental fogginess. The drug aims to strengthen brain blood vessels and reduce inflammation. The trial will in…

This study looks at whether giving thyroid hormone (levothyroxine) to people on dialysis who have slightly high TSH levels can improve their quality of life, physical strength, and heart health. About 336 adults on hemodialysis will receive either the hormone or a placebo for a y…

This study is testing a new device called the InnAVasc graft, which is placed under the skin to connect an artery and vein for easier dialysis access. About 133 adults with end-stage kidney disease who need dialysis will receive the graft. Researchers will check if the graft stay…

This study tests whether a drug called sacubitril/valsartan can help people who just started hemodialysis. The goal is to see if it reduces fluid buildup in the heart and helps the kidneys keep working longer. About 100 adults will receive either the drug or a placebo for 16 week…

This study tests whether special filters (sorption technologies) can reduce inflammation in people on long-term hemodialysis for kidney failure. About 60 adults with high inflammation levels will be enrolled. The main goal is to see if these filters lower inflammatory markers lik…

This study tests whether a manuka honey mouthwash can improve gum health in people with severe kidney disease who are on dialysis. Gum disease is very common in these patients and can lead to tooth loss. The trial will compare standard gum treatment plus honey rinse versus standa…

This study tests whether progressive muscle relaxation exercises can ease depression and fatigue in people receiving hemodialysis. Sixty patients will practice these simple, guided exercises to see if they improve mood and energy. The goal is to offer a safe, drug-free way to sup…

This study looks at whether a 6-week aerobic exercise program can lower uric acid levels and improve daily function and quality of life in people on hemodialysis. Thirty-two adults aged 40-60 will be randomly assigned to either exercise or standard care. The goal is to find a sim…

This study looks at whether a special breathing exercise program can strengthen respiratory muscles and improve quality of life in people on hemodialysis. Fifty patients aged 50 to 60 who have been on dialysis for 1-3 years will take part. The goal is to see if these exercises ca…

This study compares two common dialysis methods—high-flux hemodialysis and hemodiafiltration—to see which one causes less fatigue and helps people aged 85 and older recover faster after treatment. Each participant will try both methods for three months, acting as their own compar…

This study tests whether one-on-one support from a specially trained nurse and an exercise teacher can help people on hemodialysis become more physically active at home. The study will include 70 adults who have been on dialysis for less than a year. Researchers will measure acti…

This study tests a new device called PatenSee that uses light and sound to check the health of the blood vessel access used for dialysis, without touching the skin. About 90 adults with kidney failure on regular dialysis will participate. The goal is to see if the device works as…

This study looks at whether changing the magnesium level in the dialysis fluid can reduce blood cell activation and clotting during treatment. 15 adults on hemodialysis will have their blood and the used dialysis circuit tested after sessions with different fluid compositions. Th…