HEMODIALYSIS

This study is testing whether a 12-week course of a multi-species synbiotic (a mix of probiotics and prebiotics) can improve gut health and reduce harmful toxins in the blood of people on hemodialysis. The trial will enroll 30 adults who have been on dialysis for at least 3 month…

This study tests whether taking royal jelly supplements can reduce inflammation and slow cell aging in people with chronic kidney disease who are on hemodialysis. Thirty participants will take either royal jelly or a placebo daily for two months. Researchers will measure changes …

This study tests whether an experimental drug called AV-001 can protect the brain from injury caused by hemodialysis. The drug is designed to strengthen blood vessels in the brain and reduce inflammation. Researchers will enroll 60 adults who have been on dialysis for at least th…

This study tests whether a manuka honey mouthwash can improve gum health in people with kidney failure who are on dialysis and also have gum disease. About 150 adults will rinse with a diluted honey solution three times daily. Researchers will measure gum attachment, bleeding, pl…

This study tests a new device called the InnAVasc graft, which is surgically placed in the arm to provide a reliable access point for hemodialysis in people with end-stage kidney disease. About 133 participants will receive the graft and be followed for two years to see how well …

This study tests whether special filters (sorption technologies) can lower inflammation in people on long-term hemodialysis for kidney failure. About 60 adults with high inflammation levels will receive the filter during their regular dialysis sessions. The main goal is to see if…

This study tests whether giving a thyroid hormone supplement (levothyroxine) to dialysis patients with mild hypothyroidism can improve their quality of life and heart health. About 336 adults on hemodialysis will receive either the hormone or a placebo for up to two years. The go…

This pilot study tests a 13-week Dialectical Behavioural Therapy (DBT) skills training program for Canadians who have recently started or will soon start facility-based hemodialysis. The goal is to see if the program is feasible and helpful for improving mental health and reducin…

This study tests whether a 4-week mindfulness meditation program can improve sleep quality, reduce stress, and ease symptoms in people receiving hemodialysis. Fifty adults on dialysis will either get meditation plus usual care or usual care alone. Researchers will measure changes…

This study tests whether progressive muscle relaxation exercises can reduce depression and fatigue in people receiving hemodialysis. Sixty patients will practice these relaxation techniques, and researchers will measure changes in their mood and energy levels. The goal is to see …

This study compares two common dialysis methods—high-flux hemodialysis and hemodiafiltration—to see which one causes less fatigue and helps people aged 85 and older recover energy faster after treatment. Each participant will try both methods for three months, acting as their own…

This study tests whether personalized support from an exercise teacher and a nurse can help people on hemodialysis become more physically active at home. The study will include 70 adults who have been on dialysis for less than a year. The goal is to see if this support leads to l…

This study tests whether a 6-week aerobic exercise program (done on non-dialysis days) can lower serum uric acid levels, improve walking ability, and boost quality of life in 32 adults aged 40-60 who are on hemodialysis. Half will exercise 3 times a week; the other half will rece…

This study tests whether a set of breathing exercises, called breath booster training, can strengthen respiratory muscles and improve quality of life in people on hemodialysis. Fifty patients aged 50 to 60 will do the exercises three times a week during their dialysis sessions. R…

This pilot study looks at whether giving dialysis on the same day as surgery is better than not giving it for people with end-stage kidney disease. About 30 participants will be randomly assigned to one of two schedules. Researchers will track safety issues like electrolyte probl…

This pilot study tests whether adjusting magnesium levels in dialysis fluid can reduce harmful blood cell activation during treatment. Fifteen adults with kidney failure will try three different dialysis fluid recipes over six weeks. Researchers will measure blood cell counts and…

This study is testing a new device called PatenSee that can check the health of dialysis access points without touching the patient. About 90 adults with kidney failure who need regular dialysis will take part. The device uses light and sound to see and hear the access point, and…