Could a thyroid pill boost heart health in dialysis patients?
NCT ID NCT03977207
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether giving a thyroid hormone supplement (levothyroxine) to dialysis patients with mild hypothyroidism can improve their quality of life and heart health. About 336 adults on hemodialysis will receive either the hormone or a placebo for up to two years. The goal is to see if this common treatment actually helps this specific group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Levothyroxine (thyroid hormone supplement)
What this could lead to
If it works, this could point toward a safe way to improve quality of life and reduce heart disease risk in dialysis patients with mild hypothyroidism.
What could go wrong
This is a mid-sized trial, but the condition is mild and the benefits may be small. There is also a risk of overtreatment or side effects from thyroid hormone.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California Irvine
RECRUITINGOrange, California, 92868, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••