Can a pig thyroid extract tame hypothyroidism?
NCT ID NCT07747103
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This Phase 3 trial is testing an experimental tablet made from desiccated porcine thyroid extract, called North Star, in people with primary hypothyroidism. The study aims to see if this treatment can bring thyroid-stimulating hormone (TSH) levels into the normal range. Participants will take the extract and be monitored for safety and effectiveness over 24 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Desiccated porcine thyroid extract tablets (North Star)
- What this could lead to
- If successful, this could offer an alternative treatment option for people with primary hypothyroidism who need thyroid hormone replacement.
- What could go wrong
- This is an open-label, single-arm study, so results may be influenced by bias and lack a comparison group. The extract may not consistently control TSH levels or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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3Sync LLC
NOT_YET_RECRUITINGMiami Lakes, Florida, 33014, United States
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3Sync Research
NOT_YET_RECRUITINGPalm Springs, Florida, 33461, United States
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Accel Research
NOT_YET_RECRUITINGLakeland, Florida, 33803, United States
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Accel Research
NOT_YET_RECRUITINGLargo, Florida, 33777, United States
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ActivMed Practices and Research
NOT_YET_RECRUITINGMethuen, Massachusetts, 01844, United States
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Advanced Medical Research Institute, LLC
RECRUITINGMiami, Florida, 33147, United States
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Advanced Medical Trials, LLC
NOT_YET_RECRUITINGGeorgetown, Texas, 78628, United States
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AppleMed Research Group, LLC
RECRUITINGMiami, Florida, 33126, United States
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Boston Clinical Trials
NOT_YET_RECRUITINGBoston, Massachusetts, 02131, United States
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Charlotteville Medical Research Center, LLC
NOT_YET_RECRUITINGCharlottesville, Virginia, 22911, United States
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Coastal Carolina Research Center, LLC
NOT_YET_RECRUITINGNorth Charleston, South Carolina, 29405, United States
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M3 Wake Research
NOT_YET_RECRUITINGRaleigh, North Carolina, 27612, United States
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M3 Wake Research
NOT_YET_RECRUITINGCharleston, South Carolina, 29414, United States
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M3 Wake Research
NOT_YET_RECRUITINGChattanooga, Tennessee, 37421, United States
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M3 Wake Research
NOT_YET_RECRUITINGDallas, Texas, 75246, United States
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M3 Wake Research - Las Vegas Wellness Way
NOT_YET_RECRUITINGLas Vegas, Nevada, 89106, United States
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Olympus Clinical Research
NOT_YET_RECRUITINGSugar Land, Texas, 77478, United States
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Paradigm Clinical Research Centers, LLC
NOT_YET_RECRUITINGModesto, California, 95355, United States
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Paradigm Clinical Research Centers, LLC
NOT_YET_RECRUITINGRedding, California, 96001, United States
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Paradigm Clinical Research Centers, LLC
NOT_YET_RECRUITINGSan Diego, California, 92108, United States
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Paradigm Clinical Research Centers, LLC
NOT_YET_RECRUITINGAurora, Colorado, 80012, United States
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Paradigm Clinical Research Centers, LLC
NOT_YET_RECRUITINGBoise, Idaho, 83709, United States
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Precision Clinical Research
NOT_YET_RECRUITINGSunrise, Florida, 33351, United States
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Progressive Medicine of the Triad, LLC
NOT_YET_RECRUITINGWinston-Salem, North Carolina, 27103, United States
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Sunwise Clinical Research
NOT_YET_RECRUITINGWalnut Creek, California, 94596, United States
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