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Hypothyroidism's hidden toll on organs and muscles revealed

NCT ID NCT07707830

Knowledge-focused Sponsor: Andijan State Medical Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Aug 28, 2026 · Updated 2 times

Summary

This study looks at how hypothyroidism (an underactive thyroid) changes the size of internal organs like the liver, pancreas, and kidneys, and how it affects muscle strength and function. Researchers will measure these changes using ultrasound and physical tests in 500 adults aged 18 to 59 with hypothyroidism. The goal is to find simple markers that can help doctors spot early signs of organ and muscle involvement, improving risk assessment and care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors identify early signs of organ and muscle changes in people with hypothyroidism, leading to better monitoring and care.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly lead to new therapies. The findings may not apply to all patients with hypothyroidism.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults aged 18-59 years with a previously established diagnosis of hypothyroidism who are receiving routine outpatient or inpatient medical care at participating healthcare institutions in Andijan, Uzbekistan.

Ages

18 to 59 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-59 years. * Previously established diagnosis of hypothyroidism. * Receiving routine outpatient or inpatient care at participating healthcare institutions. * Ability to undergo ultrasonographic, anthropometric and functional assessments. * Provision of written informed consent. Exclusion Criteria: * Pregnancy or lactation. * History of thyroid malignancy. * Acute infectious or inflammatory disease at the time of enrolment. * Severe decompensated cardiovascular, hepatic or renal disease preventing study procedures. * Neurological or musculoskeletal disorders that preclude functional testing. * Refusal or inability to provide written informed consent.

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Conditions

The condition(s) this trial relates to.

hypothyroidism Motor Activity Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypothyroidism

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Andijan State Medical Institute

    RECRUITING

    Andijan, 170127, Uzbekistan

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