HYPOTHYROIDISM

This study looks at whether giving thyroid hormone (levothyroxine) to people on kidney dialysis who have slightly high TSH levels can improve their quality of life, physical strength, and heart health. About 336 adults aged 18-75 on hemodialysis will be randomly assigned to recei…

This study tests whether a combination of two thyroid medications (levothyroxine and liothyronine) works better than the standard single drug for people with hypothyroidism. The goal is to see if the combo can improve cholesterol levels and quality of life. Researchers will enrol…

This study tests a program to help doctors safely reduce or stop thyroid hormone medication in adults aged 65 and older who are getting too much or don't need it. The goal is to prevent harm from overtreatment while keeping thyroid levels healthy. About 900 participants will take…

This study looks at whether allowing more flexibility in levothyroxine (thyroid hormone) dosing can improve quality of life for older adults with hypothyroidism. Researchers will enroll 228 people aged 65 and older who take daily thyroid medication. Participants will be monitored…

This study tests if Armour Thyroid, a natural thyroid extract, works as well as the standard synthetic T4 medication for adults with hypothyroidism (underactive thyroid). About 2,800 people currently stable on synthetic T4 will switch to Armour Thyroid or stay on their current dr…

This study looks at whether hypothyroidism caused by immune checkpoint inhibitors (a type of cancer immunotherapy) can get better after stopping the immunotherapy. Researchers want to see how many patients can safely stop taking thyroid hormone medication. The study involves 107 …

This study looks at whether a specific type of strength training (nonlinear vs. linear) can improve quality of life in women with hypothyroidism. Researchers will measure thyroid hormone levels and use a questionnaire to assess physical and mental health. The goal is to find whic…

This study tests a decision support tool that uses early blood tests to predict the best dose of levothyroxine (thyroid hormone) after thyroid removal surgery. Normally, finding the right dose takes months of trial and error. The tool aims to get patients to the correct dose fast…

This study follows up to 2,500 people with thyroid problems like hyperthyroidism or hypothyroidism. Researchers aim to learn how these conditions develop, their genetic links, and how they affect patients over time. Participants receive standard medical tests and may provide bloo…

This study looks at 500 people with hypothyroidism (underactive thyroid) who take levothyroxine. Researchers want to see if measuring a different thyroid hormone, called fT3, or the ratio of fT3 to fT4, can give a clearer picture of thyroid health than current tests. The goal is …

This study follows 35 people with severe obesity who are having mini-gastric bypass surgery as part of their routine care. Researchers want to see how the surgery helps improve related health problems like type 2 diabetes, sleep apnea, high blood pressure, and fatty liver disease…