Could older thyroid patients get more flexible dosing?
NCT ID NCT06073665
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether older adults (65+) with hypothyroidism can safely take their thyroid medication (levothyroxine) with more flexible dosing. Researchers want to see if this affects quality of life, tiredness, and thinking skills. The trial involves 228 participants and compares different dosing strategies over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Levothyroxine (thyroid hormone replacement)
What this could lead to
If successful, this could show that older adults with hypothyroidism can have more flexible dosing without harming their quality of life or thinking abilities.
What could go wrong
This is a Phase 4 trial with 228 participants, so results may not apply to everyone. There is a risk that flexible dosing could lead to under- or over-treatment of thyroid levels.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Penn Medicine, Smilow Translational Research Center
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States