HEMODIALYSIS

This study tests a new device called the InnAVasc graft, which is placed under the skin to connect an artery and vein for dialysis. It includes 133 adults with end-stage kidney disease who need a graft for hemodialysis. The main goals are to see if the graft stays open and workin…

This study tests whether a drug called sacubitril/valsartan can help people who just started hemodialysis. The goal is to see if it reduces fluid buildup in the heart and helps the kidneys keep working longer. About 100 adults will receive either the drug or a placebo for 16 week…

This study looks at whether giving thyroid hormone (levothyroxine) to people on kidney dialysis who have slightly high TSH levels can improve their quality of life, physical strength, and heart health. About 336 adults aged 18-75 on hemodialysis will be randomly assigned to recei…

This study tests whether special filters (sorption technologies) can reduce inflammation in people on long-term hemodialysis for kidney failure. About 60 adults with high inflammation levels will be enrolled. The main goal is to see if these filters lower inflammatory markers lik…

This study tests a new medication called AV-001 in 60 adults who have been on dialysis for at least 3 months. The goal is to see if AV-001 can strengthen brain blood vessels and reduce inflammation, potentially preventing memory problems and thinking difficulties caused by dialys…

This study tests whether a manuka honey mouthwash can improve gum health in people with severe kidney disease who are on dialysis. Gum disease is very common in these patients and can lead to tooth loss. The trial will compare standard gum treatment plus honey rinse versus standa…

This study compares two common dialysis methods—high-flux hemodialysis and hemodiafiltration—to see which one causes less fatigue and helps people aged 85 and older recover faster after treatment. Each participant will try both methods for three months, acting as their own compar…

This study looks at whether a special breathing exercise program can strengthen the breathing muscles and improve quality of life for people on hemodialysis. Fifty patients aged 50 to 60 who have been on dialysis for 1 to 3 years will take part. The goal is to see if these exerci…

This study tests whether one-on-one support from a specially trained nurse and an exercise teacher can help people on hemodialysis become more physically active at home. The study will include 70 adults who have been on dialysis for less than a year. Researchers will measure acti…

This study looks at whether a 6-week aerobic exercise program can lower uric acid levels and improve daily function and quality of life in people on hemodialysis. Researchers will compare 32 patients aged 40-60 who either exercise or receive standard care. The goal is to find a s…

This study tests whether progressive muscle relaxation exercises can reduce depression and fatigue in people receiving hemodialysis. Sixty participants will learn a simple, drug-free technique of tensing and relaxing muscle groups. The goal is to see if this practice improves emo…

This study tests a new device called PatenSee that uses light and sound to check the health of the blood vessel access used for dialysis, without touching the skin. About 90 adults with kidney failure on regular dialysis will participate. The goal is to see if the device works as…

This study looks at whether changing the magnesium level in the dialysis fluid can reduce blood cell activation and clotting during treatment. 15 adults on hemodialysis will have their blood and the used dialysis circuit tested after sessions with different fluid compositions. Th…