Mushroom extract may fight smoke damage, early trial hints

NCT ID NCT07316400

Completed Disease control Sponsor: University of Brawijaya Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a daily supplement made from a mushroom extract (PsP) could reduce markers of oxidative stress and inflammation in 200 adults who smoke or are exposed to smoke. Participants took either PsP or a placebo for 8 weeks, and researchers measured changes in blood levels of certain chemicals linked to cell damage and inflammation. The goal is to see if this natural supplement might help protect the body from some harmful effects of cigarette smoke.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Polysaccharide peptide (PsP) from Ganoderma lucidum mushroom extract
What this could lead to: If it works, this could point toward a natural supplement to help reduce some harmful effects of smoking on the body.
What could go wrong: This is a small, early-stage trial measuring only blood markers, not health outcomes. The supplement may show no benefit or could interact with other medications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CIGARETTE SMOKING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Cigarette Smoking Inflammation inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIGARETTE SMOKING INFLAMMATION OXIDATIVE STRESS

Contacts and locations

Locations

University of Brawijaya

Malang, East Java, 65145, Indonesia

More trials for these conditions

Other studies related to the condition(s) this trial covers.