Mushroom extract may fight smoke damage, early trial hints
NCT ID NCT07316400
First seen Jan 11, 2026 · Last updated Jun 23, 2026 · Updated 31 times
Summary
This study tested whether a daily supplement made from a mushroom extract (PsP) could reduce markers of oxidative stress and inflammation in 200 adults who smoke or are exposed to smoke. Participants took either PsP or a placebo for 8 weeks, and researchers measured changes in blood levels of certain chemicals linked to cell damage and inflammation. The goal is to see if this natural supplement might help protect the body from some harmful effects of cigarette smoke.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Brawijaya
Malang, East Java, 65145, Indonesia
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Polysaccharide peptide (PsP) from Ganoderma lucidum mushroom extract
What this could lead to
If it works, this could point toward a natural supplement to help reduce some harmful effects of smoking on the body.
What could go wrong
This is a small, early-stage trial measuring only blood markers, not health outcomes. The supplement may show no benefit or could interact with other medications.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.