Psoriasis study probes hidden heart risks

NCT ID NCT01778569

Completed Knowledge-focused Sponsor: National Heart, Lung, and Blood Institute (NHLBI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 14 times

Summary

This completed study looked at 386 adults with psoriasis to understand how skin inflammation might be linked to heart and blood vessel diseases. Participants had up to seven visits over four years, including blood tests, heart scans, and optional skin biopsies. The goal was to see if inflammation from psoriasis is connected to early signs of heart disease, like artery hardening.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could clarify how skin inflammation like psoriasis affects heart health, pointing toward better screening or prevention strategies.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly test any therapy. Results may show links but not prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Inflammation inflammatory disease metabolic disease psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASE INFLAMMATION METABOLIC DISEASE PSORIASIS

Contacts and locations

Locations

National Institutes of Health Clinical Center

Bethesda, Maryland, 20892, United States

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