New drug aims to tame inflammation in kidney patients

NCT ID NCT04626505

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested an experimental drug, ziltivekimab, in 36 adults with advanced chronic kidney disease (not on dialysis) to see if it can safely reduce inflammation and related heart risks. Participants received either a low dose, a high dose, or a placebo injection every 4 weeks for 3 doses. The main goal was to measure changes in a blood marker of inflammation (hs-CRP) over 12 weeks.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome Inflammation inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ehime Medical Center

    Ehime, 791-0281, Japan