Can a gout drug slow a stiff heart valve?
NCT ID NCT05253794
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This pilot study tested whether colchicine, an anti-inflammatory drug, can slow the buildup of calcium in the aortic valve. 24 adults with mild-to-moderate aortic stenosis were randomly assigned to take colchicine or a placebo for 6 months. The study measured changes in valve calcification using a special PET scan.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Ottawa Heart Institute
Ottawa, Ontario, K1Y 4W7, Canada
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