Study explores link between diet and inflammation in obesity
NCT ID NCT02367287
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study examined how diet influences inflammation and metabolism in 393 healthy and obese adults. Researchers measured immune cells, hormones, and other markers after participants ate a high-fat meal. The goal was to better understand the complex interactions between diet, body weight, and inflammation that may contribute to chronic diseases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
393 people
The number who actually took part.
- Started
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May 2015
- Finished
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Jul 2019
- Lead sponsor
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A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Healthy people in the general population
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18-65 y * Male or female * Body Mass Index 18.5-45.0 kg/m2 (Normal to obese) Exclusion Criteria: * Pregnant or lactating women * Known allergy to egg-white protein * Systolic blood pressure greater than 140 mm Hg or diastolic blood pressure greater than 90 mm Hg measured on three separate occasions * Diagnosed active chronic diseases for which the individual is currently taking daily medication, including but not limited to: * Diabetes mellitus * Cardiovascular disease * Cancer * Gastrointestinal disorders * Kidney disease * Liver disease * Bleeding disorders * Asthma * Autoimmune disorders * Hypertension * Osteoporosis * Recent minor surgery (within 4 wk) or major surgery (within 16 wk) * Recent antibiotic therapy (within 4 wk) * Recent hospitalization (within 4 wk) * Use of prescription medications at the time of the study that directly affect endpoints of interest (e.g. hyperlipidemia, glycemic control, steroids, statins, anti-inflammatory agents, and over-the-counter weight loss aids)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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USDA, Western Human Nutrition Research Center
Davis, California, 95616, United States
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