Oat compound shows promise for inflammation in early human trial

NCT ID NCT06101784

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested avenanthramide, a natural compound found in oats, to see if it is safe and how the body processes it. Researchers gave single and multiple doses to 92 healthy volunteers and people with low-grade inflammation. The goal was to check for side effects and measure levels of the compound in the blood, not yet to prove it reduces inflammation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
avenanthramide (an oat compound)
What this could lead to
If it works, this could point toward a natural supplement to help manage low-grade inflammation.
What could go wrong
This is a very early, first-in-human study focused on safety, not on proving the compound works. The results may not lead to any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Montreal Heart Institute

    Montreal, Quebec, H1T 1N6, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.