CARDIOVASCULAR DISEASES
Clinical trials for CARDIOVASCULAR DISEASES explained in plain language.
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Could a natural compound in food help aging hearts?
Disease control CompletedThis study tests whether spermidine, a natural substance found in foods like soy and aged cheese, can improve heart and muscle health in elderly people with coronary artery disease. 180 participants aged 65 and older will receive either spermidine capsules or a placebo for a peri…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE2 • Sponsor: University of Aarhus • Aim: Disease control
Last updated Jul 01, 2026 20:00 UTC
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Could a Protein-Rich diet and strength training boost heart recovery?
Disease control CompletedThis study explores whether combining a high-protein Mediterranean diet with resistance exercise can help people with heart disease build muscle and lower their risk of future heart problems. The trial enrolls adults who have completed cardiac rehab and may have low muscle mass w…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Liverpool John Moores University • Aim: Disease control
Last updated Jul 01, 2026 20:00 UTC
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New coaching model boosts cardiac rehab use in seniors
Disease control CompletedThis study tested a coaching program called MACRO-I for adults aged 70 and older who had a heart event. The program used coaches to guide patients through starting cardiac rehab, either at a center, at home, or a mix of both. 416 participants were split into the coaching group or…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Daniel Forman, MD • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New drug Kylo-11 tested to lower hidden heart risk
Disease control CompletedThis early-phase study tested a new drug called Kylo-11 in 71 healthy adults with high levels of Lp(a), a genetic risk factor for heart disease. The main goal was to check safety and how the drug moves through the body. Researchers gave single doses at different levels to see if …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE1 • Sponsor: Kylonova (Xiamen) Biopharma co., LTD. • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New PAH pill aims to delay worsening in large trial
Disease control CompletedThis study tested a new oral drug called ralinepag in 687 adults with pulmonary arterial hypertension (PAH), a serious lung condition that makes the heart work harder. Participants took ralinepag or a placebo on top of their usual PAH medications. The main goal was to see if rali…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Fruits and veggies may rival medication for kidney health
Disease control CompletedThis completed study tested whether eating more fruits and vegetables or taking sodium bicarbonate (baking soda) tablets can slow the progression of chronic kidney disease and reduce heart risks in people with high blood pressure and kidney damage. 108 non-diabetic adults with st…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Donald Wesson • Aim: Disease control
Last updated Jun 27, 2026 13:08 UTC
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Baking soda and veggies tested as cheap kidney protectors
Disease control CompletedThis study tested whether reducing dietary acid with fruits and vegetables or sodium bicarbonate (baking soda) can slow chronic kidney disease in people with high blood pressure. 153 participants were followed for 5 years to measure kidney function and heart risk markers. The goa…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Donald Wesson • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New procedure shows promise for Hard-to-Control high blood pressure
Disease control CompletedThis study tested a procedure called renal denervation, which uses radiofrequency energy to calm overactive nerves in the kidneys, to see if it can safely lower blood pressure in people whose hypertension is not controlled by up to three medications. The study involved 337 partic…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Medtronic Vascular • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Could a seaweed supplement boost blood vessel function?
Disease control CompletedThis study tests whether a supplement made from seaweed, called rhamnan sulfate, can improve blood vessel function in middle-aged and older adults who have at least one risk factor for heart disease (like high blood pressure or obesity). Participants take the supplement or a plac…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Texas at Austin • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Can tighter blood pressure control after pregnancy save lives?
Disease control CompletedThis study tested whether a stricter blood pressure goal (below 135/85) after a pregnancy complicated by high blood pressure is better than the usual care (below 150/100). About 60 new mothers were enrolled and followed for six months. The goal is to see if tighter control is pos…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE4 • Sponsor: Alisse Hauspurg • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Watermelon shows promise for lowering blood pressure in Pre-Hypertension
Disease control CompletedThis completed pilot study tested whether eating watermelon can lower blood pressure in adults with pre-hypertension. 39 healthy overweight adults ate either 1 cup, 2 cups of watermelon, or a control (Italian ice) daily for 4 weeks. Researchers measured 24-hour blood pressure and…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Clinical Nutrition Research Center, Illinois Institute of Technology • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New device aims to pull clots from the brain in major strokes
Disease control CompletedThis completed study tested a new device called the Supernova stent retriever in 55 people with severe stroke caused by a large blood clot in the brain. The device is threaded through blood vessels to grab and remove the clot, restoring blood flow. Researchers measured how often …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Gravity Medical Technology, INC • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Lifting weights to fight transplant After-Effects: a new hope for young survivors
Disease control CompletedThis study looked at whether a 16-week strength training program can prevent or reduce late effects like muscle loss, heart disease, and diabetes in adults who had a bone marrow transplant as children. 28 survivors and a matched control group participated. The goal was to see if …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Rigshospitalet, Denmark • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Friends and family may be key to preventing second strokes
Disease control CompletedThis study tested whether using social networks (like family and friends) can help people at high risk for stroke stick to their medications and control risk factors after leaving the hospital. Researchers enrolled 720 patients and compared standard care with a social network-bas…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Changhai Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Can a gout drug cool down artery inflammation in diabetics?
Disease control CompletedThis study tested whether colchicine, a drug used for gout, can reduce inflammation in the arteries of people with diabetes who recently had a heart attack or stroke. Researchers used a special PET scan to measure inflammation in the blood vessels. 115 participants were randomly …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE3 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New daily pill could rival insulin for diabetes and heart risk
Disease control CompletedThis study tested a once-daily pill called orforglipron against insulin glargine in nearly 2,750 adults with type 2 diabetes, obesity or overweight, and increased cardiovascular risk. The main goal was to see if orforglipron could reduce major heart events like heart attacks or s…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Digital program aims to slash heart disease risk by lowering cholesterol
Disease control CompletedThis study tested a digital quality improvement program to help doctors better manage LDL (bad) cholesterol in patients with heart disease. Over 1,400 adults with established cardiovascular disease participated. The program used smartphone tools to improve treatment and follow gu…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Hospital Israelita Albert Einstein • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Soymilk study: could a daily glass cut your cholesterol?
Disease control CompletedThis study tested whether drinking unsweetened soymilk every day can lower cholesterol in adults with high levels. Twenty-five participants drank two bottles (750 mL total) daily for 8 weeks. Researchers measured cholesterol and other health markers to see if the soymilk helped i…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: National Taiwan Sport University • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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New program aims to cut heart disease risk in young cancer survivors
Disease control CompletedThis study tested a weight management program for young adult cancer survivors (ages 18-39) who have obesity and are within 5 years of finishing cancer treatment. The program combined healthy eating, physical activity, and symptom management to help reduce cardiovascular disease …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Can exercise dose improve heart health? study tests the best amount
Disease control CompletedThis study looked at how different amounts of aerobic exercise affect blood flow and fitness in 115 people with heart disease. Participants joined a cardiac rehab program and were monitored for changes in skin blood flow and oxygen use during exercise. The goal is to find the mos…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Instituto Nacional de Cardiologia de Laranjeiras • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New combo could cut bleeding and recovery time after heart procedure
Disease control CompletedThis completed study tested two strategies to reduce bleeding and artery blockage after a common heart procedure. 451 patients received either a standard or lower dose of heparin and a different compression band. The goal was to see if the new approach could shorten recovery and …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Regional Hospital of Scranton • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Diet and exercise may cut heart risks for breast cancer patients on hormone therapy
Disease control CompletedThis study looked at whether a Mediterranean diet and increased physical activity could improve heart health in 150 breast cancer survivors taking hormone therapy. Participants received counseling on diet and exercise over three months. Researchers measured changes in waist size,…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: MOHAMEDI Ilhem Sarra Manel • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Texting your way to a healthier heart: study tests simple step goals
Disease control CompletedThis study tested whether daily text messages with specific behavior change techniques could help sedentary adults at risk for cardiovascular disease walk an extra 1,000 steps per day. Over 600 participants received messages focused on goal setting, action planning, self-monitori…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE2 • Sponsor: Northwell Health • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Sound waves zap kidney fat to lower blood pressure
Disease control CompletedThis completed trial tested a new, noninvasive device that uses focused ultrasound to destroy a small amount of fat around the kidney. The goal was to lower blood pressure in people with mild hypertension who were not taking medication. 79 participants were randomly assigned to r…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Virtual rehab could be as good as In-Person for heart recovery
Disease control CompletedThis study tested a virtual world-based cardiac rehabilitation program called 'Destination Cardiac Rehab' against traditional center-based rehab. Over 2,800 adults with heart conditions participated to see if the virtual program could match or beat in-person rehab in improving he…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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New walking program shows promise for stroke recovery
Disease control CompletedThis study tested a 12-week walking program for 140 chronic stroke survivors. The program combined robotic-assisted walking with regular walking exercises. The goal was to improve walking ability, help with weight management, and lower blood pressure. Researchers wanted to find t…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Iqra National University • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Deep clean teeth to tame heart disease and diabetes?
Disease control CompletedThis study tested whether intensive dental cleaning and oral hygiene advice can improve gum health and also affect markers of heart disease and type 2 diabetes. About 200 adults with gum disease and either heart disease or diabetes (or prediabetes) took part. Researchers measured…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New drug aims to lower dangerous fat levels in the blood
Disease control CompletedThis Phase 3 study tested a drug called olezarsen in 1,478 people with very high triglycerides (a type of blood fat) and either heart disease or a high risk for it. Participants received either olezarsen or a placebo as a shot under the skin. The main goal was to see if olezarsen…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE3 • Sponsor: Ionis Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Nurse-Led phone program aims to cut stroke risk in ghana
Disease control CompletedThis study tested a nurse-guided phone program for 500 recent stroke patients in Ghana to help them manage their blood pressure at home. The program included home blood pressure monitoring, medication reminders, and education on heart health. The goal was to see if this approach …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE3 • Sponsor: Northern California Institute of Research and Education • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Blood pressure drugs tested as COVID-19 treatment in global trial
Disease control CompletedThis study tested whether common blood pressure medications (ACE inhibitors or ARBs) could improve outcomes for high-risk COVID-19 patients. Researchers enrolled 372 adults with confirmed COVID-19 who were either over 40 (outpatients) or over 18 (hospitalized). The goal was to se…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE3 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New balloon device shows promise in clearing hardened heart blockages
Disease control CompletedThis study tested a very small balloon catheter (Sapphire 3) in 170 people with severely blocked heart arteries (chronic total occlusions). The balloon was used to open the blockage before placing a stent. The main goal was to see if the device could be safely delivered, inflated…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: OrbusNeich • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Texting your way to a healthier heart after a heart attack
Disease control CompletedThis study tested whether monthly text messages with heart-health tips could help people who had a heart attack better control their risk factors and avoid future heart problems. 370 participants received either usual care or usual care plus text messages for one year. The goal w…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Fundación EPIC • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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HIV heart risk targeted: new drug shows promise in reducing arterial inflammation
Disease control CompletedThis study tested whether a drug called alirocumab, which lowers cholesterol, can reduce heart disease risk in people with HIV. The trial involved 118 adults aged 40 and older with well-controlled HIV and high heart disease risk. Participants received either alirocumab or a place…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Fitbit and coaching: a new boost for weight loss drug users?
Disease control CompletedThis study tested whether a Fitbit activity tracker combined with virtual health coaching could help people on weight loss medications (GLP-1/GIP) become more active. Fifteen participants wore a Fitbit and had up to six coaching sessions over 12 weeks. The main goal was to see if…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New heart valve passes safety check in 57 patients
Disease control CompletedThis study looked at the SAPIEN XT heart valve, which is placed through a thin tube (catheter) to fix a failed valve in the heart's right ventricle. Researchers wanted to confirm it is safe and works well. They enrolled 57 people with a narrowed or leaky heart valve conduit. The …
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Heart patients get Double-Duty blood thinners in massive trial
Disease control CompletedThis completed trial tested whether taking two blood thinners (clopidogrel and aspirin) for 12 months after a heart stent procedure is better than aspirin alone for people with multiple blocked coronary arteries. Over 8,000 patients were enrolled across 100 centers. The main goal…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE4 • Sponsor: Harbin Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New heart failure pill shows promise in Mid-Stage trial
Disease control CompletedThis Phase 2 trial tested the drug tovinontrine (CRD-750) against a placebo in 557 adults with chronic heart failure and reduced pumping ability. The goal was to see if the drug safely lowers a key heart stress marker called NT-proBNP over 12 weeks. The study is complete, and res…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE2 • Sponsor: Cardurion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New heart failure drug shows promise in early trial
Disease control CompletedThis Phase 2 study tested the safety and effectiveness of tovinontrine, an experimental drug, compared to a placebo in 303 adults with chronic heart failure with preserved ejection fraction. The main goal was to see if tovinontrine could lower a key biomarker (NT-proBNP) in the b…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE2 • Sponsor: Cardurion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New program aims to cut heart risk in rheumatoid arthritis patients
Disease control CompletedThis study tested a program to help people with rheumatoid arthritis (RA) get their cholesterol checked and treated. Many RA patients are at higher risk for heart attacks and strokes but often miss out on proper screening. The program used peer coaches and educational materials t…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Balloon catheter aims to supercharge blood flow to heart and brain during arrest
Disease control CompletedThis study tested a new device called NEURESCUE in 6 adults experiencing in-hospital cardiac arrest. The device is a balloon catheter inserted through the leg artery that inflates to redirect blood flow to the heart and brain. The goal was to see if it could be deployed quickly a…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: neurescue • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Chewing gum that might help your gums and heart?
Disease control CompletedThis study tested whether a chewing gum containing dietary nitrate (a natural compound found in leafy greens and beets) could improve gum health and heart health in adults with mild gum disease. Thirty participants were randomly assigned to use either the nitrate gum or a placebo…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Heart valve clip could cut hospital visits for heart failure patients
Disease control CompletedThis study tested a device called MitraClip, which is a small clip placed through a tube in a vein to repair a leaky mitral valve in the heart. The trial included 304 people with severe mitral regurgitation and heart failure. Half got the clip plus standard medical care, and half…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 26, 2026 14:14 UTC
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New blood pressure gadget aims for quicker, simpler heart checks
Diagnosis CompletedThis study tests whether a new device called VicorderCS can measure blood pressure accurately. The device uses a standard arm cuff and is designed to be faster and more portable than older models. Researchers will compare its readings to those taken with a traditional stethoscope…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: 80 Beats Medical • Aim: Diagnosis
Last updated Jul 01, 2026 00:00 UTC
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New device could make measuring heart health in kids easier
Diagnosis CompletedThis study tests whether a simpler device called pOpmètre can accurately measure arterial stiffness in children aged 4 to 8. Arterial stiffness is an important sign of heart and blood vessel health. The standard device, Sphygmocor, is harder to use in children. If pOpmètre works …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Nantes University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 14:02 UTC
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Eye scans may reveal hidden heart risks
Diagnosis CompletedThis study looked at whether a special eye scan (SS-OCTA) can detect signs of cardiovascular disease. Researchers compared retinal blood vessel changes to results from a standard carotid ultrasound in 42 adults. The goal was to see if the eye scan could predict the presence or se…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Northwestern University • Aim: Diagnosis
Last updated Jun 27, 2026 12:37 UTC
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New study aims to spot heart defects in newborns with simple blood test
Diagnosis CompletedThis completed study looked at 313 children to see if blood tests and advanced heart scans could help detect congenital heart disease earlier and predict which children might need surgery. Researchers compared children with heart defects to healthy controls using blood biomarkers…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Lund University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:30 UTC
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New algorithm could spare cancer patients unnecessary CT scans for blood clots
Diagnosis CompletedThis study tested whether a simple checklist and blood test (the YEARS algorithm) can safely rule out pulmonary embolism (a blood clot in the lungs) in people with active cancer, compared to the standard approach of doing a CT scan on everyone. About 700 cancer patients with susp…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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New heart risk check could spot danger earlier
Diagnosis CompletedThis study tested a new tool called the Cardiovascular Integrated Risk Tool (CVD IRT) in GP surgeries to see if it could be easily used during routine NHS Health Checks. Over 800 people aged 45-64 took part. The goal was to see if the tool works in real-world primary care and if …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Genomics PLC • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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Prepackaged Heart-Healthy meals tested in small pilot study
Prevention CompletedThis pilot study tested whether ready-to-eat meals based on the DASH diet could help lower blood pressure and reduce heart disease risk. Twenty adults ate the prepackaged meals daily for 4 weeks while researchers monitored their blood pressure and weight. The goal was to see if a…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Washington State University • Aim: Prevention
Last updated Jun 27, 2026 13:02 UTC
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Soy food may lower heart attack risk in women, large study suggests
Prevention CompletedThis large observational study followed over 135,000 Chinese women aged 40-70 to see if eating soy food reduces the risk of heart attacks and fatal heart disease. Researchers tracked participants' soy intake and heart health over time. The study aims to provide clues about diet a…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Vanderbilt University Medical Center • Aim: Prevention
Last updated Jun 27, 2026 13:00 UTC
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Heart age app trial tests digital nudge against cardiovascular disease
Prevention CompletedThis completed trial in Singapore tested whether telling people their 'heart age' and giving them a behavior-change app (HOPE-CVD) could lower their risk of heart disease. Over 1,100 adults aged 30-74 with at least a 5% risk were split into four groups, each receiving different l…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: National University of Singapore • Aim: Prevention
Last updated Jun 27, 2026 12:24 UTC
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Nutrition and exercise program aims to curb heart disease and diabetes in mexican communities
Prevention CompletedThis completed study tested a 6-month program that taught nutrition and exercise to mothers and their children (ages 7-12) in the Yaqui Valley, Mexico. The goal was to improve lifestyle habits and prevent food insecurity, malnutrition, and related health problems like heart disea…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Instituto Tecnologico de Sonora • Aim: Prevention
Last updated Jun 27, 2026 12:00 UTC
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Rural families fight heart disease and diabetes together in new study
Prevention CompletedThis study tested a family-focused lifestyle program designed to help rural Hispanic and non-Hispanic adults lower their risk for heart disease and type 2 diabetes. Over 500 participants took part in a culturally tailored program that encouraged healthy eating, physical activity,…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Gia Mudd • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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Heart-Healthy women: exercise and brain games may ward off memory loss
Prevention CompletedThis study looked at whether a home-based physical activity program and computer-based cognitive training could help prevent memory loss in older women with heart disease. 253 women aged 65 and older participated. The goal was to see if these lifestyle changes could improve memor…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Rush University Medical Center • Aim: Prevention
Last updated Jun 27, 2026 08:01 UTC
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HIV heart risk: statin pill could save lives
Prevention CompletedThis large phase 3 trial tested whether a daily statin (pitavastatin) can reduce the risk of heart attacks, strokes, and other cardiovascular events in adults with HIV who are on antiretroviral therapy. Over 7,700 participants from multiple countries took either the statin or a p…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE3 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Prevention
Last updated Jun 26, 2026 13:58 UTC
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Couples therapy for heart patients? new program aims to heal hearts together
Symptom relief CompletedThis completed trial tested an 8-week program called Healing Hearts Together (HHT) for couples where one partner has heart disease. 474 couples attended weekly group sessions focused on communication, emotional support, and heart health. The goal was to see if the program improve…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Heart device study tests virtual workouts for Women's health
Symptom relief CompletedThis study looked at whether a 12-week virtual exercise program could help women with cardiac implantable electronic devices (CIEDs) improve their physical fitness, quality of life, and mental health. Twenty women took part, doing either high-intensity interval training (HIIT) or…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Quick brain game may boost exercise in heart rehab
Symptom relief CompletedThis study tested whether a short, 15-minute brain-training task (evaluative conditioning) could help heart attack survivors exercise at a higher intensity during cardiac rehab. Twenty-four patients were split into two groups: one received training linking physical activity with …
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Could a simple under-the-tongue powder help control blood pressure?
Symptom relief CompletedThis early study tested a new way to deliver a substance that helps blood vessels relax, potentially lowering blood pressure. Fourteen healthy adults took a mixture placed under the tongue. Researchers measured changes in blood pressure and related chemicals in the blood to see i…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: EARLY_PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Exercise boosts heart health in endometrial cancer survivors
Symptom relief CompletedThis study looked at whether a 12-week program of aerobic and strength exercises could improve heart health and fitness in women who finished treatment for endometrial cancer. Thirty-three survivors in remission took part. They received exercise equipment and a Fitbit, and had he…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Jess S. Gorzelitz • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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New research could help heart failure patients get safer surgery
Knowledge-focused CompletedThis completed study looked at 260 patients with ischemic cardiomyopathy (a weak heart due to blocked arteries) who had heart surgery. The goal was to develop a personalized approach to choose the best type of surgery and predict risks and outcomes. Researchers used imaging, bloo…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Female Athletes' heart risks linked to not eating enough
Knowledge-focused CompletedThis study looked at 50 trained to elite female athletes to understand how not getting enough energy (low energy availability) might harm their hearts. Researchers measured heart disease risk factors and checked DNA changes that could be linked to these risks. The goal was to lea…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Liverpool Hope University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Could AI help pharmacists give better advice?
Knowledge-focused CompletedThis study tests whether pharmacists using a generative AI tool (ChatGPT) can provide more accurate and complete medication counseling compared to standard practice. The trial involves 136 adults with chronic conditions like diabetes, high blood pressure, or asthma who are pickin…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Petra • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Diabetes Drug's hidden effect on heart fat revealed
Knowledge-focused CompletedThis study looked at how a diabetes medicine called ertugliflozin affects fat tissue around the heart. Researchers took fat samples from 61 adults with type 2 diabetes and heart disease during heart surgery. They tested the fat in a lab to see if the drug improved how the fat cel…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: EARLY_PHASE1 • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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New blood clot drug tested in healthy volunteers – no cure yet
Knowledge-focused CompletedThis early-stage study tested a new drug called Vitalangio1 in 627 healthy adults aged 18–55 to see if it is safe and how the body processes it. Participants took either the drug or a placebo, and some took it with or without food to see how that affects absorption. The study doe…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE1 • Sponsor: Peking University First Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Website may help patients overcome statin side effects
Knowledge-focused CompletedThis study tested whether an educational website helps people who stopped taking statins due to muscle pain make informed decisions about restarting. Nearly 900 participants were randomly assigned to use the website or receive usual care. The goal was to see if the website increa…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Many heart patients skip their meds, study finds
Knowledge-focused CompletedThis study checked how well over 5,000 heart patients follow their prescribed medicine routine. Researchers asked patients about their medication habits and any side effects. The goal was to understand how many patients do not take their medicines as directed.
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: National Medical Research Center for Therapy and Preventive Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Dialysis patients wear heart monitors for a week to uncover hidden risks
Knowledge-focused CompletedThis study followed 268 adults with end-stage kidney disease on dialysis. Each participant wore a Holter heart monitor for 7 days to track irregular heartbeats. Researchers then looked for links between those heart patterns and serious outcomes like sudden cardiac death, heart at…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Gut trouble linked to hardened arteries? new study investigates
Knowledge-focused CompletedThis completed study looked at 115 people with inflammatory bowel disease (IBD) to see if their condition raises the risk of atherosclerosis, a hardening of the arteries that can lead to heart attacks and strokes. Researchers measured artery stiffness and thickness, and tracked h…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: I.M. Sechenov First Moscow State Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Blood clues may predict heart trouble after stent
Knowledge-focused CompletedThis study checked if certain blood markers can predict serious heart events like heart attack or death within a year after a stent procedure. Researchers measured two types of cells related to blood vessel health in 170 adults scheduled for a stent. The goal was to see if these …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Exercise may boost heart fitness in hodgkin survivors
Knowledge-focused CompletedThis study looked at whether exercise training can improve physical capacity and heart function in adults who survived Hodgkin lymphoma after chemotherapy and chest radiation. Forty survivors took part in fitness tests and heart monitoring. The goal was to see if exercise could r…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Can a doctor's referral to an exercise coach get people moving?
Knowledge-focused CompletedThis study tested a program where doctors refer inactive people with chronic diseases (like diabetes, heart disease, or obesity) to an exercise professional for personalized counseling. The goal was to see if this referral scheme helps people become more active compared to just g…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Erlangen-Nürnberg • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Can a simple resource list boost heart health in rural communities?
Knowledge-focused CompletedThis study tested a tool called HealtheRx, which gives African American patients in rural North Carolina a personalized list of local resources for food, housing, transportation, and more. The goal was to see if this information helps patients feel more confident finding and usin…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Sitting less, walking more: simple breaks may cut diabetes and heart risk
Knowledge-focused CompletedThis study looked at whether taking short, regular walks during long periods of sitting can lower blood sugar and cholesterol after meals—key risk factors for Type 2 diabetes and heart disease. Researchers compared the effects in normal-weight and overweight/obese South Asian adu…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Bedfordshire • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Keto diet may raise 'Bad' cholesterol differently depending on your weight
Knowledge-focused CompletedThis completed study from Penn State University looked at how a strict 4-week ketogenic diet (very low carb, high fat) affects blood cholesterol and heart health in 25 healthy adults. Researchers compared people with a healthy BMI to those with obesity to see if the diet raises '…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Penn State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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New turkish tool aims to spot depression in heart patients
Knowledge-focused CompletedThis study checked whether the Turkish version of the Cardiac Depression Scale (CDS) works well for people with heart disease. Researchers tested 360 Turkish adults with various heart conditions to see if the scale accurately measures depression. The goal is to give doctors a rel…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Kırıkkale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Heart and mind: new study explores the hidden links between cardiovascular disease and mental illness
Knowledge-focused CompletedThis completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Ningbo No. 1 Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can we fix genetic counseling? new study says yes!
Knowledge-focused CompletedThis study tested new ways to make genetic counseling more helpful for people from all backgrounds. Over 1,000 adults completed surveys and allowed their counseling sessions to be recorded. The goal was to see if different counseling methods lead to better experiences, especially…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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New genomic risk model aims to make personalized prevention accessible to all
Knowledge-focused CompletedThis study tested a program called GRACE that helps primary care patients assess their risk for diseases like heart disease, cancer, and liver disease using family health history. Researchers enrolled 245 patients from five clinics, including low-resource settings, to see how man…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Oakland study tests new way to make schools follow PE laws and fight health gaps
Knowledge-focused CompletedThis study looked at whether a special audit and feedback tool could help elementary schools in Oakland follow physical education laws better. The goal was to increase students' physical activity and reduce health inequalities. Researchers worked with 35 schools that serve mostly…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of California, Berkeley • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Stand up for your health: simple swap may lower blood sugar
Knowledge-focused CompletedThis study tested whether replacing sitting with standing or walking during daily life could improve blood sugar levels in South Asian adults who are overweight or obese. Eighteen participants followed two regimens: one with more sitting and one with less sitting. The goal was to…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Bedfordshire • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Fatty liver may be a hidden clue for heart trouble
Knowledge-focused CompletedThis study looked at whether fatty liver disease can be an early warning sign for heart disease, separate from known risk factors. Researchers measured blood markers of blood vessel damage in 63 people aged 50-69 who were already at high risk for heart problems. The goal was to b…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: IMDEA Food • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Heart attack patients use telemedicine to stay home
Knowledge-focused CompletedThis study tested whether giving heart attack patients remote monitoring devices to use at home could reduce the need for hospital readmissions. 337 participants with high cardiovascular risk took part. The goal was to see if telemedicine could safely provide necessary diagnostic…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Which drug protects the heart better in giant cell arteritis?
Knowledge-focused CompletedThis study looked at over 1,600 people with giant cell arteritis, a condition that inflames blood vessels and raises heart risks. Researchers compared tocilizumab and methotrexate to see which better prevents heart attacks, strokes, or death. Using French health data, they analyz…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Groupe français d'étude des Maladies Inflammatoires de loeil • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Study explores heart specialist access for HIV patients in minority groups
Knowledge-focused CompletedThis study looked at health records of over 2,000 people with HIV from racial and ethnic minority groups to see if seeing a heart specialist (cardiologist) helps prevent heart disease. Researchers tracked who visited a cardiologist and for how long, up to 5 years. The goal is to …
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Just 3 days of sitting more may harm older adults' blood vessels and blood sugar
Knowledge-focused CompletedThis study looked at what happens when active older adults (55+) reduce their physical activity for just 3 days. Researchers measured changes in blood sugar after meals and blood vessel function, comparing them to younger adults. The goal was to see how quickly inactivity can aff…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Leryn Reynolds • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Why do people with spinal cord injury gain weight? new study investigates.
Knowledge-focused CompletedThis study followed 42 adults with spinal cord injury for one year after leaving rehab. Researchers tracked what they ate, how active they were, and their mood to understand why weight gain happens. The goal is to use this information to design better programs that help people wi…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Smart math could help spot High-Risk heart surgery patients
Knowledge-focused CompletedThis study looked at 485 patients who had coronary artery bypass surgery to see if a computer method called fuzzy logic could better predict who is at risk of dying. Fuzzy logic is a way to handle uncertain information, similar to how doctors think. The goal is to create a tool t…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Istanbul University - Cerrahpasa • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Sitting less, living better: new study targets diabetes in black seniors
Knowledge-focused CompletedThis study worked with Black adults aged 55 and older who have type 2 diabetes to understand why they sit for long periods and how to help them sit less. Researchers used interviews and activity monitors to learn about the social and personal factors that lead to prolonged sittin…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: PHASE2 • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Study links poverty and depression to higher heart disease risk in minorities
Knowledge-focused CompletedThis study looked at how social factors like income, housing, and stress, along with depression, affect blood vessel health in low-income racial and ethnic minority adults. Researchers measured depression, anxiety, stress, and social needs using questionnaires. The goal was to un…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Processed food diet linked to heart risk – small study tests if cutting them helps arteries
Knowledge-focused CompletedThis study tested whether reducing ultra-processed foods (UPF) can improve blood vessel function in middle-aged adults, a key factor in heart disease. Seventeen participants ate either a diet with no UPF or one with high UPF for six weeks. Researchers measured changes in artery f…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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New study aims to prevent dangerous blood pressure drops during dialysis
Knowledge-focused CompletedThis study tested whether teaching dialysis staff and providing support to patients could reduce episodes of dangerously low blood pressure during treatment. Over 1,400 patients across multiple clinics took part. The goal was to make dialysis sessions safer and more stable.
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Study tests digital referrals to boost WIC enrollment in pregnancy
Knowledge-focused CompletedThis study looked at whether online referrals from doctors to the WIC food program help more pregnant women sign up. About 240 pregnant women on public insurance or uninsured took part. Some got usual care, others got a direct digital referral, and some also spoke with a dietitia…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Geisinger Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Did a simple phone call keep chronic patients out of the hospital?
Knowledge-focused CompletedThis study tested whether a systematic phone call from a medical student, supervised by a general practitioner, could reduce hospitalizations in patients with chronic heart or mental health conditions during the COVID-19 lockdown in France. Over 22,000 patients aged 70 and older …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Which risk score best predicts heart surgery survival?
Knowledge-focused CompletedThis study looked at 320 adults who had heart surgery to see how well two different risk scores (EuroSCORE-II and POSPOM) predict the chance of dying in the hospital. Researchers calculated each patient's scores before surgery and compared them to what actually happened. The goal…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Istanbul University - Cerrahpasa • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Scientists investigate why high 'Bad' cholesterol harms heart repair cells
Knowledge-focused CompletedThis completed study examined blood samples from 40 adults to see if high levels of lipoprotein (a), a type of cholesterol, are linked to fewer or different blood vessel repair cells. Participants with high Lp(a) were compared to those with normal levels. The goal was to better u…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Canadian Medical and Surgical Knowledge Translation Research Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Heart data harvest: no treatment, just software testing
Knowledge-focused CompletedThis study gathered information from 100 people undergoing a standard heart procedure called left atrial appendage closure. Researchers used the data to test a software tool that measures heart structures from echocardiograms. No new treatments or procedures were given—only routi…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Anumana, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Can a simple workshop help arab women better manage their heart health?
Knowledge-focused CompletedThis study had two parts. First, researchers held focus groups with Arab women in East Jerusalem to understand their health literacy needs. Then, they tested a 4-session workshop designed to improve how these women communicate with their doctors and learn about heart disease. Abo…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Hadassah Medical Organization • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Can a workplace program boost heart health for care workers?
Knowledge-focused CompletedThis study tested a worksite wellness program designed to reduce stress and improve cardiovascular health among long-term care workers. 159 staff and residents participated. The program included health promotion and safety education, and researchers also looked at whether healthi…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Massive study reveals best diabetes drugs for your heart
Knowledge-focused CompletedThis study looked at nearly 242,000 adults with type 2 diabetes to compare different glucose-lowering medications and their effects on heart health. The goal was to help patients and doctors choose the best treatment based on age, sex, race, and kidney function. The main focus wa…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Kaiser Permanente • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Massive study tracks COVID-19 aftereffects for 18 months
Knowledge-focused CompletedThis completed study followed 6,000 adults who had COVID-19 symptoms and were tested for the virus. Participants completed online surveys every 3 months for 18 months to track long-term health issues like fatigue, brain fog, and heart problems. The goal was to better understand t…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Small study reveals hidden links between job stress and obesity in poor communities
Knowledge-focused CompletedThis study looked at how stress, behavior, and social factors affect weight loss and heart health in people from disadvantaged backgrounds. 15 adults with overweight or obesity took part. Researchers measured weight, waist size, and heart health over time to understand what helps…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Can air purifiers help heart patients? small study tests new approach
Knowledge-focused CompletedThis study tested an indoor air pollution intervention called AIRWISE in 20 adults aged 55 and older with heart disease. Participants received personal air cleaners, a color-changing air quality monitor, and educational materials. The goal was to see if they would use these tools…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Montana • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Silent heart danger: can painless ischemia predict heart attacks?
Knowledge-focused CompletedThis study looked at whether silent myocardial ischemia (reduced blood flow to the heart without chest pain) increases the risk of heart problems or death in people with coronary heart disease. Researchers followed participants for one to three years. The goal was to better under…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Your facebook posts might reveal your heart health risk
Knowledge-focused CompletedThis completed study looked at whether digital data like social media posts and online searches can help predict heart disease risk and healthcare use. Researchers analyzed language from Facebook, Twitter, and other platforms from 781 adults aged 30-74. The goal was to find patte…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Soul food makeover: can a traditional diet boost brain health?
Knowledge-focused CompletedThis study tested whether a brain-healthy version of soul food, called the MIND+SOUL diet, is practical and well-liked by older African Americans at risk for heart disease and cognitive decline. Twenty-nine participants aged 55 and older took cooking classes and received dietary …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Researchers hunt for genetic clues to sudden cardiac death
Knowledge-focused CompletedThis study aimed to find out if certain genes make people more likely to die suddenly from a heart problem. Researchers looked at the DNA of 2,500 people to see if specific gene variations were linked to sudden cardiac death. No treatments or interventions were given; the goal wa…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Heart attack mystery: study probes why 1 in 5 victims have no known risks
Knowledge-focused CompletedThis completed study looked at 1,000 heart attack patients to understand why some have no standard risk factors like smoking, high blood pressure, or diabetes. Researchers compared these 'SMuRF-less' patients to those with risk factors, examining their medical history, lab tests,…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Heart health mystery: does mitochondria fuel racial gap?
Knowledge-focused CompletedThis study looked at whether tiny cell parts called mitochondria contribute to higher blood pressure and worse blood vessel health in Black adults. Researchers gave 31 middle-aged and older adults a supplement called MitoQ or a placebo for 8 weeks. The goal was to understand the …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Auburn University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Tiny study sips on Drink's brain & body benefits
Knowledge-focused CompletedThis small study looked at whether drinking a KETO5 XOGenius beverage every day could improve markers of heart health, thinking skills, and body measurements like weight and waist size. Six healthy adults aged 18 to 50 took part. The goal was to gather early information, not to t…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: The University of Texas at Arlington • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Fish oil pill may make 'bad' cholesterol less dangerous, study finds
Knowledge-focused CompletedThis study tested whether taking a high-dose fish oil supplement (E-EPA) for one month changes how LDL ('bad' cholesterol) clumps together in 68 healthy adults. Researchers measured blood fats and LDL stickiness before, during, and after the supplement period. The goal was to und…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Wihuri Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Plant-Based diet may lower cholesterol in genetic heart condition
Knowledge-focused CompletedThis study tested whether a whole-food plant-based diet, compared to a standard North American diet, can lower LDL cholesterol in 50 adults with heterozygous familial hypercholesterolemia (HeFH). Participants followed each diet for 28 days in a crossover design. Researchers also …
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Laval University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:37 UTC
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Can smarter school programs cut heart risks in kids?
Knowledge-focused CompletedThis study looked at how to make school-based physical activity and nutrition programs work better for children in Texas. Researchers tested different support methods—like mentoring, extra resources, and contests—to see which helped schools deliver these programs most effectively…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Texas A&M University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:10 UTC
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Vegetarian diet linked to lower risk of dementia, heart disease, and more in massive study
Knowledge-focused CompletedThis completed study followed over 18,000 Taiwanese Buddhists to see if a vegetarian diet is linked to a lower risk of chronic diseases like dementia, depression, heart disease, stroke, gout, cataracts, gallstones, and urinary tract infections. Researchers compared health records…
Matched conditions: CARDIOVASCULAR DISEASES
Sponsor: Dalin Tzu Chi General Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:57 UTC
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Can asking patients about their needs reduce hospital visits?
Knowledge-focused CompletedThis study looked at two ways to assign care coordinators to older adults (65+) with heart disease or risk factors. One method used patients' own reports of difficulty coordinating care, while the other used usual triggers like hospital discharge. The goal was to see which approa…
Matched conditions: CARDIOVASCULAR DISEASES
Phase: NA • Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:18 UTC