New procedure shows promise for lowering Hard-to-Control blood pressure

NCT ID NCT02439775

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This study tested a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys, to see if it can safely lower blood pressure in people whose hypertension is not controlled by up to three medications. The study involved 337 participants and measured blood pressure changes over six months. The goal was to find a new way to help manage high blood pressure, a condition that increases the risk of heart disease and stroke.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HYPERTENSION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Alfred Hospital

    Melbourne, Victoria, 3004, Australia

  • AnMed Health

    Anderson, South Carolina, 29621, United States

  • Aurora St. Luke's Medical Center

    Milwaukee, Wisconsin, 53215, United States

  • Baptist Medical Center Jacksonville

    Jacksonville, Florida, 32207, United States

  • Barnes-Jewish Hospital

    St Louis, Missouri, 63110, United States

  • Baylor Heart & Vascular Hospital

    Dallas, Texas, 75226, United States

  • Cardiff and Vale University Health Board - University Hospital of Wales

    Cardiff, United Kingdom

  • Cardiology Associates Research LLC

    Tupelo, Mississippi, 38801, United States

  • Centennial Medical Center

    Nashville, Tennessee, 37203, United States

  • Charleston Area Medical Center

    Charleston, West Virginia, 25304, United States

  • Clinique Pasteur

    Toulouse, France

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Emory University Hospital Midtown

    Atlanta, Georgia, 30308, United States

  • Galway University Hospital

    Galway, Ireland

  • Hamilton Heath

    Hamilton, Ontario, Canada

  • Hattiesburg Clinic

    Hattiesburg, Mississippi, 39401, United States

  • Heart Center Research, LLC

    Huntsville, Alabama, 35801, United States

  • Herzzentrum Leipzig, Universitätsklinik

    Leipzig, 04289, Germany

  • Higashi Takarazuka Satoh Hospital

    Takarazuka, Hyōgo, Japan

  • Hippokration General Hospital of Athens

    Athens, 11527, Greece

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Imperial College Healthcare NHS Trust

    London, W12 0HS, United Kingdom

  • Iowa Heart Center

    West Des Moines, Iowa, 50266, United States

  • Jichi Medical University Hospital

    Shimotsuke, Tochigi, 329-0498, Japan

  • Klinikum Wels-Grieskirchen

    Wels, 4600, Austria

  • Memorial Hospital Jacksonville

    Jacksonville, Florida, 32216, United States

  • Minneapolis Heart Institute Foundation

    Minneapolis, Minnesota, 55407, United States

  • Mitsui Memorial Hospital

    Chiyoda City, Tokyo, 101-8643, Japan

  • Mount Sinai Medical Center

    New York, New York, 10029, United States

  • North Shore University Hospital

    Manhasset, New York, 11030, United States

  • Oregon Health & Science University Hospital

    Portland, Oregon, 97239, United States

  • Piedmont Heart Institute

    Atlanta, Georgia, 30309, United States

  • PinnacleHealth Cardiovascular Institute

    Harrisburg, Pennsylvania, 17011, United States

  • Providence Hospital

    Southfield, Michigan, 48075, United States

  • Royal Bournemouth Hospital

    Bournemouth, United Kingdom

  • Royal Devon & Exeter NHS Foundation Trust

    Exeter, EX2 5DW, United Kingdom

  • Royal Perth

    Perth, Australia

  • Saint Barnabas Medical Center

    Livingston, New Jersey, 07039, United States

  • Saiseikai Nakatsu Hospital

    Osaka, Japan

  • Sana Kliniken Lübeck

    Lübeck, 23560, Germany

  • Shonan Kamakura General Hospital

    Kamakura, Okamoto, Japan

  • St Joseph Mercy Oakland

    Pontiac, Michigan, 48341, United States

  • St. George Hospital

    Kogarah, Australia

  • St. Michael's Hospital

    Toronto, Ontario, Canada

  • Stanford Hospital and Clinics

    Stanford, California, 94305, United States

  • Tallahassee Research Institute

    Tallahassee, Florida, 32308, United States

  • The Miriam Hospital

    Providence, Rhode Island, 02906, United States

  • University General Hospital of Thessaloniki (AHEPA)

    Thessaloniki, 54621, Greece

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Kentucky

    Lexington, Kentucky, 40536, United States

  • Universitäts-Herzzentrum Freiburg - Bad Krozingen GmbH

    Bad Krozingen, 79189, Germany

  • Universitätsklinikum Erlangen

    Erlangen, 91054, Germany

  • Universitätsklinikum des Saarlandes

    Homburg, 66421, Germany

  • Washington DC VA Medical Center

    Washington D.C., District of Columbia, 20422, United States

  • Weill Cornell Medical College/The New York Presbyterian Hospital

    New York, New York, 10021, United States

  • Yale New Haven Hospital

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.