Heart valve clip shows promise in reducing hospital stays

NCT ID NCT01920698

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 23 times

Summary

This study tested a device called MitraClip that clips a leaky heart valve to help it close better. 304 people with severe mitral regurgitation and heart failure were randomly assigned to get either standard care alone or standard care plus the MitraClip procedure. The goal was to see if the device could reduce deaths and unplanned hospital stays for heart failure over two years.

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Contacts and locations

Locations

  • APHP Hôpital Henri Mondor

    Créteil, France

  • Aphp Hopital Bichat

    Paris, France

  • CH Annecy Genevois

    Metz-Tessy, 74370, France

  • CHRU La Cavale Blanche

    Brest, France

  • CHRU La Milétrie

    Poitiers, France

  • CHRU de Tours

    Tours, France

  • CHU Caen

    Caen, 14000, France

  • CHU Rouen

    Rouen, France

  • CHU d'Angers

    Angers, 49933, France

  • CHU de Grenoble

    Grenoble, 38700, France

  • Centre Cardiologique du Nord

    Saint-Denis, France

  • Centre Chirurgical Marie Lannelongue

    Le Plessis-Robinson, France

  • Centre chirurgicale Ambroise Paré

    Neuilly-sur-Seine, 92200, France

  • Chu de Besancon

    Besançon, France

  • Chu de Bordeaux

    Bordeaux, France

  • Chu de Lille

    Lille, France

  • Chu de Montpellier

    Montpellier, France

  • Chu de Nancy

    Nancy, France

  • Chu de Nantes

    Nantes, France

  • Chu de Rennes

    Rennes, France

  • Chu de Strasbourg

    Strasbourg, France

  • Chu de Toulouse

    Toulouse, France

  • Clinique Cardiologique Saint Gatien

    Tours, France

  • Clinique Du Millenaire

    Montpellier, France

  • Clinique Pasteur

    Toulouse, 31076, France

  • Clinique du Tonkin

    Villeurbanne, France

  • Groupe Hospitalier La Salpétrière

    Paris, 75013, France

  • Groupement Hospitalier Est

    Bron, France

  • Hopital de La Timone

    Marseille, France

  • Hôpital Européen Georges Pompidou

    Paris, 75015, France

  • Hôpital Gabriel Montpied

    Clermont-Ferrand, 63000, France

  • Hôpital Nord

    Saint-Etienne, 42055, France

  • Hôpital Pasteur

    Nice, 06001, France

  • Hôpital Saint-Joseph

    Marseille, 13285, France

  • Hôpital privé Clairval

    Marseille, France

  • Hôpital privé de Parly 2

    Le Chesnay, 78150, France

  • Hôpital privé le Bois

    Lille, France

  • Institut Arnault Tzanck

    Saint-Laurent-du-Var, France

  • Institut Hospitalier Jacques Cartier

    Massy, France

  • Institut Mutualiste Montsouris

    Paris, 75014, France

Conditions

Explore the condition pages connected to this study.