Attention deficit-hyperactivity disorder

This phase 3 trial tests whether a new formulation of dexmethylphenidate (CTx-1301) can improve attention and reduce ADHD symptoms in adults for up to 16 hours. Participants take an optimized dose (25, 37.5, or 50 mg) and complete math tests in a simulated classroom. The study co…

This study tests an oral capsule called AK0901 (AZSTARYS) in children aged 6 to 12 with attention deficit hyperactivity disorder (ADHD). The trial compares the drug against a placebo to see if it reduces ADHD symptoms like inattention and hyperactivity. Researchers measure sympto…

This completed trial in Xishui, China, tested a community-based program for 3,571 adults aged 35 and older who were at high risk for COPD and had mental health symptoms. The program included lung function tests, digital mental health support, smoking cessation help, and health ed…

This study tested whether N-acetylcysteine (NAC), an antioxidant drug, can improve motor skills and learning in children with neurofibromatosis type 1 (NF1). Twenty-five children aged 8 to 16 took NAC or a placebo for 8 weeks. The goal was to see if NAC is safe and helps with mov…

This study tested a noninvasive brain stimulation technique (transcranial random noise stimulation) to see if it could reduce cravings in 225 adults with substance use disorder plus another psychiatric condition like ADHD, bipolar disorder, or schizophrenia. The approach targeted…

This study tested the long-term safety of a daily medication called centanafadine in 680 children and teens (ages 4-17) with ADHD. The drug is a non-stimulant capsule taken once a day. Researchers tracked side effects over time to see if it is safe for extended use. The trial is …

This study tested three ways to help children aged 7-11 with ADHD: a computer-based cognitive training program using a virtual classroom, the medication methylphenidate, and supportive talk therapy. Fifty-one children took part to see which approach best improves attention and re…

This Phase 3 trial tested a once-daily extended-release capsule called centanafadine in 315 adults with both ADHD and anxiety (generalized or social anxiety). For 8 weeks, participants received either the drug or a placebo. The study measured changes in ADHD symptoms using a clin…

This study tested whether tolcapone, a drug used for Parkinson's disease, could change how people with both alcohol use disorder and ADHD respond to alcohol and make decisions. 23 adults completed the trial, which involved taking tolcapone or a placebo and then undergoing alcohol…

This study tested the drug Qelbree (viloxazine) in 161 adults with ADHD who also had mood symptoms. Participants took the medication for several weeks, and researchers tracked changes in ADHD symptoms using a standard rating scale. The goal was to see if Qelbree is both safe and …

This study tested a summer program called Summer Academy for 124 young children with behavior problems who were about to start kindergarten. The program aimed to improve their school readiness and behavior. Researchers measured progress right after the program and again six month…

This study tested whether repeated low doses of LSD (called MM120) can safely help adults with ADHD. Fifty-three adults took either the drug or a placebo, and researchers measured changes in ADHD symptoms using a standard rating scale. The goal was to see if this approach could b…

This study looked at whether a brain-computer interface (BCI)-based attention training program, used alone or with medications like methylphenidate or citicoline, can improve attention and executive function in school-age children with ADHD. 174 children participated in this real…

This early-stage study tested a drug called NFC-1 in 30 adolescents aged 12-17 with ADHD who also have specific genetic changes affecting brain receptors. The goal was to check the drug's safety and how the body processes it, while also looking for signs it might reduce ADHD symp…

This study tested whether a team-based care model can help people with both opioid use disorder and mental health issues like depression or anxiety. 254 adults in primary care received either full collaborative care for both conditions or just mental health support. The goal was …

This completed study tested whether a special diet plus a nutritional supplement called T-2 could improve thinking skills, sleep, and overall health in 76 people with Down syndrome, autism, or ADHD, aged 2 to 35. Participants followed either the diet alone, the diet plus suppleme…

This completed study tested whether a Mediterranean diet could improve metabolic syndrome markers in 30 hospitalized adults with psychiatric conditions. Participants followed either a Mediterranean diet or a standard hospital diet for 8 weeks, then switched. Researchers measured …

This study tested a virtual reality application to help diagnose Attention Deficit Hyperactivity Disorder (ADHD) in children aged 8 to 12. The goal was to see if a 3D immersive environment could better measure attention and behavior compared to standard tests. Thirty children wit…

This study tested a web-based simulation to help college students with ADHD prescriptions avoid giving away or misusing their medication. About 250 students from three universities used the program, which taught them how to say no to requests for their pills and how to talk to th…

This study tested whether giving teens with ADHD and their parents a question list or a short video before a doctor visit helps them talk more openly and get better care. About 126 English-speaking teens aged 11-17 with ADHD took part. The goal was to see if these tools improve s…

This study tests a non-invasive brain stimulation technique called tACS in 50 children and teens aged 6-18 with ADHD. The goal is to see if a mild electrical current applied to the scalp can improve attention and executive function. Participants will receive both real and sham st…

This study tested a counseling program called Youth Friendship Bench SA for young women aged 18-25 in South Africa who had symptoms of depression, anxiety, or stress. The program included individual and group counseling sessions, plus optional text reminders. The goal was to see …

This study tests whether cognitive behavioural therapy for insomnia (CBT-I) can improve sleep and ADHD symptoms in adolescents aged 12 to 18 who have both ADHD and insomnia. Participants receive either CBT-I plus usual care or usual care alone. The goal is to see if addressing in…

This study tested whether Collaborative Problem Solving (CPS), a behavioral approach that teaches caregivers to address children's underlying thinking skill deficits, can improve executive function and reduce behavioral symptoms in 54 youth receiving home-based mental health care…

This study tested a structured online program for parents of children with autism or ADHD. 90 families took part to see if the program could lower parental stress, improve coping skills, and boost social support. Researchers compared parents who received the program to those who …

This study tested a personalized brain-training method called neurofeedback for children with ADHD. 51 children participated, and the training was tailored to each child's unique brain patterns. The goal was to see if this approach could improve attention and reduce ADHD symptoms…

This pilot study tested whether adding cognitive behavioral therapy (CBT) to usual care helps reduce irritability and suicidal thoughts in children aged 8 to 12 with anger and aggression issues. 46 children were assigned to either CBT plus usual care or usual care alone. The ther…

This study tested whether a 4-week program using active video games (exergames) on the Nintendo Switch could help adults with mental illness feel better and stay motivated. Twelve participants were split into two groups: one played exergames, the other continued their usual routi…

This Phase 2 trial tested a new drug called EB-1020 SR (centanafadine) in 45 adult men with ADHD. The goal was to see if it could reduce symptoms like inattention and hyperactivity. Participants took the drug or a placebo for a few weeks, and researchers measured changes using a …

This study tested a 6-week program called BUILT for families with children aged 6 to 12 who have ADHD. The program teaches healthy habits around sleep, nutrition, and exercise to help improve focus and behavior. Researchers measured changes in physical activity, sleep, diet, and …

This study tested whether adding a virtual reality (VR) module that helps children imagine future events could improve standard brain-training exercises for kids with ADHD. Eighty children aged 5 to 12 took part, with half doing only the standard training and half also using VR h…

This study tested whether smelling lemon essential oil for 5 minutes could improve attention in 52 children aged 9-16 with ADHD who were not on medication. The children were randomly assigned to inhale either lemon oil or a placebo before taking attention and memory tests. Result…

This study tested a program called 'My DEER Compassion' that teaches self-compassion skills to children with ADHD. 96 children in Hong Kong, along with their parents, took part in sessions to learn how to be kinder to themselves. The goal was to see if this could improve their em…

This study tested a non-invasive device that gently stimulates a nerve on the forehead (trigeminal nerve) during sleep to see if it can reduce ADHD symptoms in children ages 7 to 12. Over 200 children used either the active device or a sham (inactive) device nightly for 4 weeks. …

This study looked at the safety and tolerability of the drug Azstarys in 123 children aged 4 to 5 with ADHD over 12 months. Researchers monitored sleep, weight, and height changes, as well as how well the drug controlled ADHD symptoms. The goal was to see if this medication could…

This Phase II trial tested PDC-1421, a capsule made from a plant extract, in 99 adults with ADHD. Participants were randomly assigned to receive the capsule or a placebo for up to 8 weeks. The goal was to see if the treatment could reduce ADHD symptoms and to check its safety.

This study tested a Spanish-language program called Unstuck and On Target with 20 families in Ecuador. Children aged 8-11 with autism or ADHD took part in an 8-week program to improve flexibility and problem-solving. The goal was to see if the program was practical and helpful fo…

This study tested whether a once-daily capsule called centanafadine helps reduce ADHD symptoms in children aged 4 to 12. Over 500 children took either the drug or a placebo for 6 weeks. Researchers measured changes in ADHD rating scales to see if the drug works better than a suga…

This study looked at whether a long-acting medication called guanfacine (TAK-503) can help children and teenagers aged 6 to 17 with ADHD who did not get better with standard stimulant treatments. The study had two parts: first, participants were randomly assigned to receive guanf…

This study tested whether phosphatidylserine supplements with or without DHA (an omega-3 fat) could improve thinking skills in children with ADHD. 45 children aged 10-14 who had never taken ADHD medication took either a placebo or one of three supplement formulas daily for 8 week…

This study tested whether a brain-training technique called neurofeedback, combined with virtual reality (VR), could improve attention and self-control in children with ADHD. 138 children aged 7-12 took part in 16 training sessions over 8 weeks. The goal was to see if this approa…

This study tested a new type of therapy called reminder-focused positive psychiatry (RFPP) for teenagers who have both ADHD and PTSD. The goal was to see if the therapy is acceptable and helpful for reducing symptoms. Eleven teens took part, and the study measured how well they l…

This completed trial tested whether LEGO therapy can improve social skills in 50 adolescents aged 10–14 with high-functioning autism. Participants attended 12 weekly 90-minute group LEGO sessions over 3 months. Researchers compared their social skills to a control group who conti…

This study looked at whether creating personalized profiles for children with disruptive behavior disorders (like ADHD or oppositional defiant disorder) and their parents could help predict which therapy works best. Researchers tested two common treatments—child cognitive behavio…

This study tested whether playing a specially designed multitask game for 25 minutes a day, at least 5 days a week, could improve attention in children aged 8-12 with ADHD. Forty children participated, and researchers measured changes in attention using a computer test called TOV…

This study tested a new parenting program called ADAPT for depressed parents of children aged 6 to 10 with emotional and behavioral difficulties. The program combines emotion regulation skills with parenting techniques. The goal was to see if the program is feasible and acceptabl…

This study tested a summer program called STRIPES, where trained peers helped ninth graders with ADHD get ready for high school. 72 students were randomly assigned to the program or to regular school services. Researchers tracked grades, attendance, and ADHD symptoms to see if th…

This study tested a video-based therapy called Focused Acceptance and Commitment Therapy (FACT) for parents of children with special health needs, like ADHD or autism. The goal was to see if it could reduce stress, anxiety, and depression. 104 parents took part, and the therapy w…

This study tested whether ongoing Tai Chi and mindful movement classes could help children with ADHD improve motor control, attention, and reduce symptoms. Fifteen children took part in one-hour classes twice a week for a year. Researchers measured changes in cognitive control, m…

This study tested whether adding a gentle brain stimulation technique (tDCS) to online therapy could help adults with ADHD. 30 participants received either real or fake tDCS alongside a 3-month online therapy program. The goal was to see if the combination improved attention and …

This study looked at whether taking Lion's Mane mushroom extract daily for two months can improve memory and attention in healthy, working women aged around 40-60. Participants took either the extract or a placebo pill and completed thinking and memory tests at several points. Th…

This study tested a special sleep program for teenagers with ADHD who also have sleep problems. The program combines cognitive behavioral therapy with sleep tips and planning skills. Researchers wanted to see if better sleep could also improve ADHD symptoms and daily life. The st…

This study tested whether virtual reality glasses or white noise headphones could reduce pain and anxiety in 48 children with ADHD during dental procedures. The children were distracted with cartoons or white noise while dentists worked. Researchers measured pain through behavior…

This Phase 3 trial tested whether solriamfetol, a drug already approved for sleep disorders, can reduce ADHD symptoms in adults. Over 500 participants took either a daily dose of solriamfetol or a placebo for six weeks. The study measured changes in attention and hyperactivity us…

This study tested two high-tech teaching methods—AI-assisted learning and virtual reality classrooms—in 90 children aged 8-15 with ADHD. Over 12 weeks, researchers measured changes in ADHD symptoms and thinking skills. The goal was to see if these digital tools can help without m…

This study tested a telehealth program that teaches caregivers skills to manage ADHD-related behaviors and sleep problems in preschoolers aged 3-5 at risk for ADHD. 46 families participated, and researchers measured changes in ADHD symptoms and sleep habits. The goal is to provid…

This study tested a 10-week peer support program called 'Paths to everyday life' for adults with mental health difficulties. Participants were randomly assigned to either the peer support group plus usual services, or usual services alone. The goal was to see if the program impro…

This study looked at whether two types of structured exercise—Gince Zumba (rhythm-based aerobic dance) and Square Stepping (patterned steps on a mat)—could improve thinking, movement, and behavior in 51 children with ADHD. Kids were randomly assigned to one of the exercise groups…

This study tested a 10-week program of biofeedback and breathing exercises in children and teens aged 6-18 with ADHD. The goal was to see if these techniques could reduce ADHD symptoms and improve heart rate variability. The small, completed trial involved 12 participants and use…

This study tested the Triple P parenting program for mothers of children aged 6-13 with ADHD. The program teaches strategies to reduce behavior problems and boost mothers' confidence. 67 mothers took part, with some receiving the program and others not. Researchers measured chang…

This study tested a new medication called CTx-1301 (dexmethylphenidate) for children and teens aged 6 to 17 with ADHD. The goal was to see if it reduces ADHD symptoms better than a placebo. 103 participants took either the drug or a placebo, and researchers measured changes in AD…

This study looked at whether stimulant medication can reduce loss of control eating in children aged 8 to 13 with ADHD. Ten children were followed for 3 months after starting stimulants. Researchers measured changes in eating episodes and behaviors to see if treating ADHD symptom…

This study looked at whether high-dose omega-3 fatty acids can reduce ADHD symptoms in children aged 6-12 who have high inflammation levels. Fifteen children took omega-3 supplements for 12 weeks. Researchers measured changes in ADHD symptoms and inflammatory markers to see if om…

This study tested a therapist-guided online program called AMOR for pregnant women and new mothers with ADHD. 31 participants listened to podcasts and attended online group sessions. The goal was to see if the program was easy to use and helpful for managing ADHD, stress, anxiety…

This study tested whether playing a dance-based video game (Just Dance 2024) could improve attention, mood, and self-control in young adults with ADHD. Sixty-nine participants aged 18-24 were randomly assigned to dance gaming, stationary biking, or music listening for 30 minutes.…

This study tested whether a virtual reality (VR) program can help young adults aged 18-25 with ADHD concentrate better while studying or doing homework. Sixty participants used a VR headset, with some also receiving real-time feedback on their focus levels. The goal was to see if…

This study tested a combined exercise program (aerobic, balance, coordination, and strengthening) in 30 children aged 7–12 with ADHD. The goal was to see if exercise improves motor skills, physical fitness, and thinking. The program lasted several weeks and included warm-up, main…

This study tested a parenting program called the Nurtured Heart Approach to see if it could reduce ADHD symptoms like inattention and hyperactivity in children ages 6 to 8. Parents or guardians of 104 children with or suspected of ADHD were randomly assigned to either start the p…

This study tested a new parent support program delivered via text messaging. The program includes six educational videos teaching strategies to help children with ADHD-like behaviors handle daily transitions. 52 parents of children aged 4-10 participated. The study measured how m…

This study tested whether a special diet that removes certain foods (oligoantigenic diet) can reduce core ADHD symptoms in children aged 6 to 16. Fifty children with ADHD were randomly assigned to either a regular healthy diet or the restricted diet for three months. Researchers …

This study tested four different doses of SPN-810 (molindone) in 78 children aged 6 to 12 with ADHD and serious conduct problems. The main goal was to see if the drug is safe and tolerable. Researchers measured behavior changes using a special rating scale. The trial is complete,…

This study tested a light therapy called transcranial photobiomodulation (tPBM) to see if it could safely reduce autistic traits and ADHD symptoms in children and teens. 38 participants aged 9 to 17 with ADHD and at least moderate autism symptoms received the treatment. The goal …

This study looked at whether adding music activities like playing harmonica and drums to occupational therapy can improve attention and thinking skills in children with ADHD. Thirty-nine children aged 6 to 17 took part. After six weeks, both standard and music-based therapy helpe…

This study tested whether methylphenidate, a drug often used for ADHD, can help children aged 6 to 12 with childhood apraxia of speech speak more clearly. The trial involved 18 children who took the drug or a placebo in a crossover design. The main goal was to see if the drug imp…

This study tested whether a structured physiotherapy program—including breathing exercises, balance training, and relaxation techniques—could reduce stress, anxiety, and depression in 117 children aged 6 to 18 with autism or ADHD. Participants were randomly assigned to either the…

This study tested a 10-session dog-assisted therapy program for 60 adults with severe mental illness. The goal was to see if spending time with trained therapy dogs could help participants build positive mental health behaviors like communication and socialization. Researchers me…

This study looked at whether atomoxetine, a medication for ADHD, can reduce impulsive behavior in adults aged 18-45 with moderate ADHD. Researchers measured impulsivity using questionnaires after a single dose and after two weeks of daily treatment. The goal was to see if the dru…

This study looked at whether a non-invasive brain training method called neurofeedback can help veterans who have had a mild traumatic brain injury and still suffer from chronic headaches, trouble sleeping, and attention problems. 87 veterans were randomly assigned to receive neu…

This study tested whether a biofeedback video game called Mightier can help children aged 8-12 with emotional dysregulation. 183 kids were randomly assigned to play the game at home or receive usual care for 6 months. Researchers tracked symptoms, parent stress, and healthcare co…

This study looked at whether giving iron supplements to children with ADHD, restless legs syndrome, and low iron levels could improve their symptoms. Twelve kids aged 10-15 took iron for 3 months. Researchers measured changes in brain iron, blood iron, and symptoms using sleep mo…

This study looked at whether Auri Super Mushroom Daily Gummies can help adults aged 30 and older who struggle with forgetfulness, lack of focus, low energy, and low mood. Over 8 weeks, 35 participants took two gummies each day and completed tests and surveys about their thinking,…

This study tested a non-medication sleep program for 88 adults with depression, bipolar disorder, or ADHD who also had insomnia. Participants received either the sleep program or standard sleep hygiene advice. The goal was to see if the program could improve sleep quality and red…

This study looked at whether playing in virtual reality (VR) can improve cognitive skills like attention and problem-solving in children with ADHD. Fourteen children aged 7-12 with stable medication took part. Researchers used a special test to measure thinking abilities before a…

This study tested whether listening to white noise or seeing visual pixel noise can improve attention in children with ADHD. Sixty children, some with ADHD and some without, completed eye-tracking tasks while exposed to these noises. The goal was to see if the noise could help th…

This study tested a 6-week supervised physical activity program for university students dealing with mild-to-moderate mental health issues like stress, anxiety, or feeling isolated. Seventeen students took part in group exercise sessions including walking, aerobics, and strength …

This study tested a digital therapeutic device that combines driving simulations and memory exercises to improve attention and reduce hyperactivity in children with ADHD. About 120 children aged 6 to 12 took part, with some using the active device and others a placebo version. Th…

This study tested whether adding a therapy dog to standard social skills training could help children with ADHD. Thirty-nine children took part, some receiving dog-assisted sessions and others only social skills training. Researchers measured ADHD symptoms, self-esteem, and stres…

This study tested whether a self-hypnosis smartphone app called Hypnotidoo could improve attention and reduce anxiety in children aged 7 to 12 with ADHD who were already taking methylphenidate. The app offers short, screenless audio sessions with stories and breathing exercises. …

This pilot study tested a music breathing therapy for children with ADHD and their caregivers. The therapy involved six weekly group sessions combining music, breathing exercises, and games. The goal was to see if it could boost resilience and reduce emotional and behavioral symp…

This study tested a 12-week program where children with ADHD worked with horses as part of occupational therapy. The goal was to see if it helps with emotional control, daily functioning, and participation in activities. Fifty children aged 6 to 12 took part, and researchers meas…

This study tested whether a smartphone app (BHQ) can reliably monitor social anxiety symptoms in adults, and whether a computer-based attention training called gaze-contingent music reward therapy (GC-MRT) reduces those symptoms. Forty adults with social anxiety disorder used the…

This pilot study tested a program called PRE-CARE for 54 low-income families of preschoolers with ADHD symptoms. The program helps families find and enroll in community resources like food assistance or housing support. Researchers wanted to see if this approach could reduce ADHD…

This study looks at whether children with ADHD are more likely to have very flexible joints (benign joint hypermobility) and if a certain blood marker differs. Researchers will compare 171 children aged 6 to 12—some with ADHD and some without—using physical exams and blood tests.…

This study tested whether a 10-week recovery program, co-led by a peer with mental illness and a professional, is feasible for people with mental illness in Taiwan. Twenty participants completed the program, which focused on recovery concepts, strengths, and goal setting. Researc…

This study looked at two ways to assess ADHD in children aged 8-17: a brief protocol (medical history, interview, rating scales) and a comprehensive one that also includes neuropsychological testing. Researchers wanted to see if the shorter method is as reliable, valid, and cost-…

This study tested a web application called PRATICAdr 2.0, designed to help healthcare workers on sick leave due to common mental disorders like depression or anxiety return to work. The app helps coordinators track progress and improve communication. Researchers compared workers …

This study tested whether artificial intelligence (AI) can realistically simulate conversations between a therapist and a person with a mental health problem. Researchers used 520 simulated sessions to see if the AI could follow proper therapy techniques. The goal is to use these…

This study looked at how thinking skills and brain activity differ in people who self-harm compared to those who don't. Researchers interviewed 316 adults and gave them thinking tests, with some also having brain scans. The goal was to better understand self-harm to help create m…

This completed study looked at sleep problems in over 1,100 children and adults with specific learning disabilities (like dyslexia or dyspraxia), with or without ADHD. Participants filled out online questionnaires about their sleep habits. The goal was to find out how common diff…

This study looked at how healthy adults decide where to look in a busy scene, like finding Waldo in a crowded picture. Researchers tracked eye movements while people viewed images with different colors and motion to understand how the brain highlights important spots. The goal wa…

This study looked at brain activity in adults with ADHD while they performed tasks that required stopping an action. Researchers used EEG to measure electrical signals in the brain. The goal was to understand the brain processes behind impulse control problems in ADHD. No treatme…

This study looked at how centanafadine, a potential ADHD treatment, affects the body when taken with common stimulant medicines. Forty healthy adults took part to measure changes in blood pressure, heart rate, and drug levels. The goal was to understand possible interactions, not…

This pilot study tested whether personalized medication experiments could help teens with ADHD and their parents make better decisions about future medication use. Thirty-one parent-teen pairs (teens aged 11-15) completed a medication experiment chosen together. The goal was to s…

This study looked at how nicotine from dissolvable tablets affects attention in 40 adults who occasionally use nicotine pouches. Participants tried tablets with different nicotine amounts (0 to 2 mg) and took attention tests after 15 minutes and 2 hours. The goal was to understan…

This study looked at whether being socially excluded (ostracized) affects the memory of children with ADHD. Twenty-four kids played a computer ball-tossing game where they were eventually left out, and their memory was tested before and after. The goal was to see if emotional dys…

This completed study at Rutgers University looked at how the brain and body communicate in 30 people with conditions like autism, ADHD, Alzheimer's, and Parkinson's. Participants performed natural movements like walking and pointing while their brain, heart, and motion signals we…

This study tested a smartphone app that gives parents of children with ADHD quick tips and feedback on their parenting. 34 families took part, and the app sent messages at random times to see if parents used more positive skills right after. The goal was to see if parents liked t…

This study tested whether an artificial intelligence tool could help therapists deliver better behavior therapy to minority adolescents with ADHD. Researchers worked with three community mental health agencies and 51 teens. Therapists received either AI-assisted supervision or st…

This study tested a program called Recovery Bridge, where trained peer specialists (people with lived experience of mental illness) helped veterans leaving a psychiatric hospital connect to outpatient care and community life. Fifteen veterans took part to see if the program was f…

This study looked at whether giving 7-11-year-old children in Shanghai a daily breakfast with fruits and vegetables could improve their thinking, mood, and attention. Over 250 kids took part, receiving a balanced breakfast every day for 12 weeks. Researchers measured changes in c…

This completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …

This study looked at whether the design of a common ADHD screening questionnaire (the ASRS) influences how people answer. Researchers wanted to see if shading and grouping certain answer choices made it easier for patients to guess which responses lead to a positive screen. 587 a…

This study looked at whether a new drug called EB-1020 has abuse potential in 80 healthy adults who use stimulants recreationally. Participants received single doses of EB-1020, d-amphetamine, or placebo, and rated how much they liked the drug. The goal was to see if EB-1020 prod…

This study tested whether an anti-stigma training program for healthcare providers improves attitudes toward people with mental illness or substance use problems. About 485 staff and clients from six health centers took part, with three centers receiving the training and three no…

This study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers checked 427 patients at 11 hospitals in Switzerland and Germany. They also explored whether age, gender, or type of disorder made insomnia more likely.

This study looked at whether taking two smaller capsules of centanafadine (a potential ADHD medication) works the same as taking one larger capsule. 44 healthy adults took both versions at different times to compare how the drug enters the blood. The goal was to confirm the doses…

This study tested a modified behavioral parent training program for children with ADHD who also have peer problems. The program aimed to increase parent engagement, especially for parents with their own ADHD or depression symptoms. Thirty-three parents participated, and researche…

This study looked at whether methylphenidate, a common ADHD medication, changes levels of brain inflammation markers in children aged 6 to 11. Researchers measured three inflammation-related substances in the blood of 42 children before and after 3 months of treatment. The goal w…

This study looked at whether a personalized training program could improve driving skills in 90 teens with ADHD (ages 15-18) who hadn't started driving lessons. Teens were split into three groups: one received the special training, one got educational materials, and one got no in…

This study looked at whether a single dose of methylphenidate (Ritalin) changes how people with both ADHD and alcohol use disorder respond to alcohol-related cues. Thirty-one adults aged 18-25 completed brain scans, EEG, and behavioral tests after taking either the drug or a plac…

This completed study looked at 500 children aged 5 to 18 to understand how factors around birth, thinking abilities, and social-emotional skills are linked to learning difficulties and developmental disorders like ADHD or autism. Researchers compared children with and without the…

This study explored whether a summer psychosocial program could improve emotional control, behavior, and school readiness in 323 children aged 4-7 with ADHD or disruptive behaviors. Researchers measured changes in emotion regulation, ADHD symptoms, social skills, and academic rea…

This study tested an 8-month program called 'Meaningful Activities and Recovery' (MA&R) for people with mental illness. The program helps people take part in activities that matter to them. 139 adults took part to see if the program improves activity engagement, recovery, and qua…

This completed study looked at whether playing white noise during reading and writing tests helps children aged 8-13 with ADHD and specific learning disorders. Thirty children took the same tests twice—once with white noise and once without—to see if the sound improved their spee…

This study tested a resource package designed to help caregivers use behavioral interventions for children showing hyperactive, inattentive, or impulsive behaviors. Twenty caregivers of children in grades K-5 in the Philadelphia area used the package at home. The research team co…

This study tested a program called iCOT to improve how occupational therapy interns communicate with patients in mental health settings. The program included online training and feedback from patients, supervisors, and experts. Researchers compared interns who received iCOT to da…

This study looked at 84 children with ADHD to see if the type of ADHD they have affects their pain threshold. Researchers measured how much pressure caused discomfort in different body areas. The goal was to understand if certain ADHD subtypes are linked to chronic pain or differ…

This study tested whether a systematic phone call from a medical student, supervised by a general practitioner, could reduce hospitalizations in patients with chronic heart or mental health conditions during the COVID-19 lockdown in France. Over 22,000 patients aged 70 and older …

This study looked at whether adults with ADHD are more likely to relapse into drinking after completing a detox program. Researchers followed 113 people for 12 weeks, using interviews and questionnaires to assess ADHD and other mental health conditions. The goal was to see if ADH…

This study tested whether a mild electrical current applied to the scalp (tDCS) could temporarily improve attention and self-control in adults with ADHD. 83 people, including those with ADHD and healthy volunteers, completed tasks measuring focus and decision-making while receivi…

This study looked at how children with ADHD perform when they have to do two tasks at the same time, like walking while naming animals. Researchers compared 60 children (some with ADHD, some without) to see differences in motor and thinking skills. The goal was to better understa…

This study tested how different capsule versions of the ADHD drug centanafadine are absorbed in the body. 174 healthy adults took part to see if a single high-dose capsule works the same as two lower-dose capsules, and whether food changes absorption. No treatment was given; the …

This study tested different parts of a family navigation program to see which ones work best for helping low-income and minority families get mental health services for their children. 312 children aged 3-12 who showed signs of behavioral health concerns took part. The goal was t…

This study looked at whether giving students with ADHD extra time on exams actually helps them perform better. Researchers tested 103 students, some with ADHD and some without, giving them either 25% or 50% more time to complete a test. The goal was to see if extra time improves …

This study used artificial intelligence to predict how engaged people would be in online therapy and how much their symptoms would improve. Researchers analyzed data from over 6,600 adults who took part in a digital psychotherapy program. The goal was to create fair and accurate …

This study tested a program to help kindergarten teachers recognize that some children may be mistakenly diagnosed with ADHD simply because they are younger than their classmates. 62 children who were born just before the school cutoff date took part. Teachers learned about this …

This study looked at whether whole genome sequencing (a complete read of a person's DNA) can help diagnose leukodystrophies, a group of rare brain diseases that are hard to identify. Researchers enrolled 236 children with white matter abnormalities on brain scans but no known gen…

This study created and tested a mobile app called VetEd for student veterans dealing with mental health issues like depression, PTSD, or anxiety. The goal was to help them manage academics, mental health, and find resources. Researchers worked with 13 veterans to see if the app w…

This completed study looked at 224 adults who already had at least one psychiatric condition to see how many also had undiagnosed ADHD. Researchers measured how often ADHD was missed and tracked quality of life in those diagnosed. The goal is to highlight the need for better dete…

This study tested whether children with ADHD are more likely to produce false memories compared to children without ADHD. Researchers used a word-list task called the DRM paradigm, where children heard lists of related words and later recalled them. The study involved 28 children…

This study tested whether a type of brain stimulation called intermittent theta burst stimulation (iTBS) can improve working memory in 14 adolescents with ADHD. Each participant received one session each of iTBS, standard TMS, and fake TMS. Brain activity was measured before and …

This study looked at whether the ADHD Rating Scale-IV can detect changes in attention problems in children with epilepsy. Researchers followed 173 children aged 6 to 15 who had both epilepsy and ADHD. They compared scores over 12 to 16 weeks in treated versus untreated children t…