Allergic disease

This study tests whether upadacitinib, a drug already approved for eczema, can help people who have both atopic dermatitis (a type of eczema) with moderate to severe itching and a hard-to-treat autoimmune liver disease called cholangitis. The drug works by blocking a pathway invo…

This study explores whether giving people with mild-to-moderate eczema a straightforward treatment plan using only Opzelura cream helps them stick to their medication routine. Participants apply the cream twice daily until their skin clears, then as needed. Some participants also…

This study tests a drug called nemolizumab in toddlers aged 6 to 23 months with moderate-to-severe atopic dermatitis (eczema) that hasn't improved with creams or ointments. The goal is to see how the drug moves through the body, if it is safe, and if it helps control the conditio…

This study tests an experimental pill called ENV-294 for adults with moderate-to-severe atopic dermatitis (eczema). About 200 participants will take either one of three doses of ENV-294 or a placebo daily for 12 weeks. Researchers will measure changes in eczema severity, symptoms…

This study tests whether an Ayurvedic treatment that targets digestion and gut health can reduce allergy symptoms and immune markers in people with allergic rhinitis (hay fever). 104 adults aged 18-40 with confirmed allergies will receive either the Ayurvedic treatment plus stand…

This study tests a new cream called VC005 for people aged 12 and older with mild to moderate atopic dermatitis (eczema). The goal is to see if the cream can clear or nearly clear the skin rash better than a cream without medicine. About 360 participants will use either the study …

This early study will test whether a daily omega-3 cream and serum can change the balance of bacteria on eczema-affected skin. Ten adults with eczema will apply the treatment for 14 days, and researchers will measure four types of bacteria before and after. The study is explorato…

This Phase 2 trial tests whether adding benralizumab (a drug already used for asthma) to standard corticosteroid treatment can help people with DRESS syndrome recover faster and spend fewer days in the hospital. DRESS is a rare, severe allergic reaction to certain medications tha…

The ROOT study is testing a personalized nutrition program for pregnant women. Participants receive standard prenatal care plus customized diet and lifestyle plans based on their genes and nutrient levels. The goal is to see if this approach can lower the chances of preterm birth…

This study looks at whether switching to a pill called ivarmacitinib can help people with moderate-to-severe eczema (atopic dermatitis) who did not get enough relief from standard injectable drugs. About 300 adults will take the pill for 16 weeks. The goal is to see if their skin…

This study tests if giving children with egg allergy a tiny amount of egg every day (oral immunotherapy) helps them outgrow the allergy faster. About 40 children will take part, and each year they will be tested to see if they are still allergic. The goal is to compare how quickl…

This study tests a new drug called MG-K10 in 180 teens aged 12-17 with moderate-to-severe eczema that hasn't responded well to creams. The drug is given as a shot every two weeks for a year. Researchers will check if it clears skin and reduces itching better than a placebo.

This study tests a treatment called sublingual immunotherapy (SLIT) for children ages 1-11 with cashew allergy. For 18 months, children receive daily drops under the tongue to see if they can safely eat more cashew without a reaction. The goal is to reduce allergy severity, not c…

This early-stage study tests a new drug called cizutamig in about 20 adults with IgE-mediated allergies, including food allergies. The main goal is to see if the drug can safely lower IgE levels, which are antibodies that trigger allergic reactions. Researchers will also monitor …

This large study aims to create a digital screening and management system for adults with asthma and allergies. Nearly 10,000 participants will use a smartphone platform to track symptoms and receive guidance on three non-drug strategies: avoiding allergens (like dust mites), inc…

This study compares two prescription creams, tacrolimus and crisaborole, for treating mild to moderate eczema in children and teens aged 2 to 20. Both creams are steroid-free and aim to control inflammation without the side effects of long-term steroid use. Over 8 weeks, 72 parti…

This Phase 2 study tests a new biologic drug called AK139 in 168 adults with moderate-to-severe atopic dermatitis (eczema) that hasn't improved with creams. Participants will receive either AK139 or a placebo by injection. The study aims to see if AK139 can safely clear skin and …

This phase 3 study tests an injectable drug called MG-K10 for people aged 12 and older with moderate-to-severe atopic dermatitis (eczema) that hasn't improved with creams. About 498 participants will receive either MG-K10 or a placebo to see if it safely reduces skin redness, itc…

This study tests a daily dissolving film placed under the tongue to treat dust mite allergic rhinitis (hay fever). About 250 adults in China will use either the active film or a placebo for one year. The goal is to see if the film reduces sneezing, stuffiness, and the need for re…

This Phase 2 trial tests an experimental drug called CMS-D001 in 160 adults with moderate to severe atopic dermatitis (eczema) that hasn't responded well to creams. Participants will take one of three doses of the drug or a placebo daily for several weeks. The main goal is to see…

This study tests whether clearing Staphylococcus aureus bacteria from the skin can reduce eczema severity in people with atopic dermatitis. Researchers will enroll 100 participants aged 6 and older with moderate-to-severe disease. The goal is to see if decolonization improves ski…

This early-phase trial is testing whether inhaling tiny particles from stem cells (called small extracellular vesicles) can safely help people with both allergic rhinitis and asthma. About 18 adults will receive either the active treatment or a placebo via nebulizer daily for two…

This Phase 2 trial tests two forms of peanut oral immunotherapy in 57 people aged 4 to 30 with peanut allergy. One group gets standard blanched peanut protein, the other gets autoclaved (high-pressure heated) peanut protein, both in gradually increasing doses. The goal is to see …

This study compares two steroid-free ointments—crisaborole and tacrolimus—for treating mild-to-moderate eczema in 148 Pakistani patients aged 2 and older. Researchers will measure skin improvement and side effects over 8 weeks to see which works better and is safer. The goal is t…

This phase 3 trial tests an injection called ADSTEM for adults with moderate-to-severe atopic dermatitis (eczema) that hasn't responded well to standard treatments. About 286 people aged 19 to 70 will receive either the study drug or a placebo. The main goal is to see if the inje…

This phase 3 trial compares a new injectable drug, GS101, to the established treatment Dupixent for adults with moderate-to-severe atopic dermatitis (eczema). About 572 participants will receive either GS101 or Dupixent every other week for a year. The main goal is to see if GS10…

This study tests whether adding a traditional Chinese medicine powder called Modified Shenling Baizhu Powder to standard asthma inhalers can improve symptom control in people with allergic asthma. Researchers will enroll 400 adults aged 18 to 80 who have persistent asthma and a s…

This study will test the drug ivarmacitinib in 1,000 people aged 12 to 75 with moderate-to-severe atopic dermatitis (eczema). Participants take a daily pill for up to 52 weeks, with the option to adjust the dose. Researchers will measure how well the drug clears skin rashes and r…

This study tests whether the steroid prednisolone can slow the decline in lung function for people with fibrotic hypersensitivity pneumonitis, a lung disease caused by inhaling certain substances. About 120 adults with mild to moderate lung impairment will receive either predniso…

This Phase 3 trial tests a medicated foam called OPA-15406 (difamilast) for atopic dermatitis (eczema) in children aged 2 and older, and infants under 2. About 198 participants will apply the foam twice daily for 8 weeks. The main goal is to see if the foam clears or nearly clear…

This study tests a new injectable drug called SIM0278 for adults with moderate to severe atopic dermatitis (eczema) that needs systemic treatment. About 184 participants will receive either a low, medium, or high dose of SIM0278 or a placebo. The main goal is to see how much ecze…

This Phase 3 trial tests a medicated foam called OPA-15406 (difamilast) for adults with atopic dermatitis, a common skin condition causing red, itchy rashes. About 156 participants will apply the foam or a placebo twice daily for 4 weeks. The goal is to see if the foam clears or …

This study follows 39 children with cashew allergy who previously received oral immunotherapy (OIT) with cashew protein. After 8 more months of OIT, they will stop treatment for 4 weeks and then take a food challenge to see if they can safely eat cashews without ongoing therapy. …

This study tests whether crisaborole 2% ointment works better than tacrolimus 0.1% ointment for children aged 2-18 with mild to moderate eczema. 66 children will apply one of the creams twice daily for 28 days. The main goal is to see how many achieve clear or almost clear skin b…

This study tests whether AI-powered decision trees can help general practitioners better diagnose and manage allergies. About 600 patients with suspected allergies will be enrolled, and doctors will use an app that suggests next steps based on symptoms. The goal is to see if this…

This study tests whether specially modified pork (alpha-gal knockout) causes fewer allergic reactions than regular pork in people with alpha-gal syndrome. Each of the 160 participants will eat both types of pork on different days to see which one is safer for diagnosis. The goal …

This study will check if a new physical exam called Said's test can accurately diagnose biceps tendon injuries in the shoulder. Researchers will test 144 adults, including those with shoulder injuries and healthy volunteers. Two doctors will perform the new test and standard test…

This study will check if measuring IgE antibodies to two shrimp proteins (tropomyosin and hemocyanin) in the blood can accurately diagnose shrimp allergy in children. About 129 kids with suspected shrimp allergy will take part. They will have a food challenge, skin test, and bloo…

This study tests a special PET probe that targets a protein called DDR2, which is linked to lung scarring in interstitial lung disease. Researchers will scan 50 patients to see if the probe can accurately detect the disease and also check for related cognitive problems. The goal …

This study aims to validate an Italian version of a widely used questionnaire for screening periodontitis (gum disease). Researchers will also develop an enhanced version with additional questions and test how accurately it identifies people with the condition. About 495 adults a…

This study tests a new radioactive imaging agent called 68Ga-SFB6-ZN01, which is designed to attach to a protein found on many cancer cells. 98 adults with confirmed or suspected cancer will receive a single injection of the agent and then have a PET/CT scan. The goal is to see i…

This study aims to find the best concentration of Blomia tropicalis (a type of dust mite) extract for allergy skin testing. About 30 adults with known dust mite allergies will receive small pricks with different extract strengths to see which causes a reaction similar to a standa…

This study tests whether a specific mix of probiotics can prevent allergies in breastfed infants who received antibiotics within their first month of life. Researchers will give the probiotic or a placebo to 400 babies and track allergy development, gut bacteria changes, and grow…

This study tests whether a special package of bathing, skincare, and allergen exposure advice can prevent food allergies in infants at risk. Researchers will compare the package to usual care in 64 newborns. Parents will follow recommendations like delaying the first bath and avo…

This study tests whether leaving the white, creamy coating (vernix caseosa) on a newborn's skin for at least 24 hours after birth can prevent eczema (atopic dermatitis) during the first year of life. Over 1,300 mother-infant pairs in Chile will be randomly assigned to either keep…

This study tests whether an injection called stapokibart can reduce nasal allergy symptoms like runny nose, congestion, sneezing, and itching in adolescents aged 12 to 17 with seasonal allergic rhinitis (hay fever). Participants receive either stapokibart or a placebo alongside t…

This study tests whether two experimental antibodies, given alone or together, can reduce eye allergy symptoms caused by cat dander. About 570 adults and children aged 8 and older with confirmed cat allergy will receive either the antibodies or a placebo. The main goal is to see …

This study looks at whether lowering salt in your diet can make eczema less severe. Forty adults with eczema will eat a low-salt diet for 24 weeks. For 5 weeks they'll take salt pills, and for another 5 weeks they'll take placebo pills, to see the real effect of sodium. Researche…

This phase 2 trial tests the safety of stapokibart injection in 15 teenagers aged 12-17 with seasonal allergic rhinitis (hay fever). Participants receive the drug alongside their usual allergy treatments. The study focuses on side effects and how the body processes the drug, not …

This study looks at how well RHINOSEDAL works for people aged 8 and older with a stuffy nose caused by colds, allergies, or sinus issues. About 126 participants will use the treatment as prescribed and report their symptoms over 6 days. The goal is to see if it provides meaningfu…

This study tests whether adding oral iron supplements to standard eczema treatment can reduce skin symptoms and improve quality of life in adolescents aged 12 to 16 with mild to moderate atopic dermatitis. Researchers will also check if iron levels in the blood affect how well th…

This study tests a gel called VC005 on adults with mild to moderate atopic dermatitis (eczema). About 120 participants will use either the gel or a placebo to see if it safely reduces skin redness, itching, and rash. The goal is to ease symptoms, not cure the condition.

This study tests if Dymista nasal spray safely eases allergy symptoms like sneezing, stuffy nose, and itchy eyes in Chinese teenagers aged 12 to 17. About 100 participants will use the spray twice daily for two weeks. The goal is to see if symptoms improve, not to cure allergies.

This study tests a new nasal spray called PL-14 Allergy Blocker in about 120 adults with seasonal allergies. Unlike regular allergy sprays, PL-14 is drug-free and works by forming a gel-like barrier in the nose to block allergens. The study compares it to a simple saline spray ov…

This study tests a gel made from hyaluronan (HA35) to see if it can quickly relieve moderate-to-severe itching from conditions like eczema, insect bites, and hives. About 30 adults will apply the gel once, and researchers will check itch levels at several time points up to 24 hou…

This study tests a cream called roflumilast 0.15% for itching in people with mild to moderate atopic dermatitis (eczema). About 40 participants aged 12 and older will apply the cream once daily for 4 weeks. Researchers will track how patients describe their itch and other skin se…

This early-stage study tests a new drug called HXN5003 in 28 healthy adults to see if it is safe and how the body processes it. The drug is being developed for atopic dermatitis (eczema). Participants receive either the drug or a placebo, and researchers monitor for side effects …

This early-stage trial is testing an experimental drug called IBI3033 in 16 adults with moderate-to-severe atopic dermatitis (eczema). The main goal is to check if the drug is safe and how the body processes it. Participants will receive either IBI3033 or a placebo injection over…

This study tests whether adding moxibustion—a traditional heat therapy—to standard allergy medicine can safely reduce symptoms like sneezing, stuffiness, and runny nose in people with allergic rhinitis. About 60 adults with a cold-type allergy will receive either standard care al…

This study looks at whether removing the adenoids (with or without tonsils) can improve allergy symptoms in children aged 3 to 12 who also have enlarged adenoids and tonsils. Researchers will compare surgery to standard medication by tracking symptom scores and allergy markers in…

This study compares two common treatment combinations for allergic rhinitis (hay fever) in adults: a nasal steroid spray plus an oral antihistamine versus a nasal steroid spray plus an oral antileukotriene. The goal is to see which combo better relieves symptoms like sneezing, st…

This study tests whether medications that calm mast cells (ketotifen and cromolyn) can safely reduce persistent symptoms like fatigue, pain, and brain fog in people who had a tick-borne illness. Fifty adults aged 21-65 will receive either one of these drugs or a standard antihist…

This early-stage study tests a new injection called JYB1904 in 12 teenagers aged 12-17 with allergies like hay fever, asthma, or food allergies. The main goal is to see if the drug is safe and how the body processes it. Participants will be closely monitored for side effects and …

This study looks at whether breast cancer patients can safely stop taking allergy-preventing medications before weekly paclitaxel after two doses without a reaction. Researchers want to see if stopping these drugs improves quality of life, since they can cause side effects like i…

This study will test the safety of a new biologic drug called stapokibart, given as a shot, in 400 adults with seasonal allergic rhinitis (SAR). Participants are already prescribed the drug by their doctor. The main goal is to track any side effects. This is an open-label study, …

This study tests an injection called JYB1904 for people with year-round allergies (perennial allergic rhinitis). The goal is to see if it can reduce symptoms like runny nose, congestion, and sneezing better than a placebo. About 135 adults who already use nasal sprays will receiv…

This study will test whether a partially hydrolyzed whey protein formula can help ease mild allergy symptoms in infants. About 160 babies with mild skin, stomach, or breathing issues will be randomly assigned to get either the special formula or a standard cow's milk formula. Res…

This study tests whether a medicated cream called crisaborole works better than a placebo cream for people with mild to moderate eczema. About 270 people aged 12 to 50 will apply the cream twice daily for four weeks. The goal is to see if the cream can clear or nearly clear the e…

This study tests a new medicine called AK139 for people with moderate to severe seasonal allergic rhinitis (hay fever). About 111 adults aged 18-65 with at least a 2-year history of seasonal allergies will receive either AK139 or a placebo. The main goal is to see if AK139 reduce…

This study tests whether giving a steroid and antihistamine just 1 hour before a CT scan is as safe as the standard 4-hour premedication for people with contrast allergies. It involves 540 emergency department adults who need a CT for a serious condition. If successful, it could …

This phase 3 study tests an oral tablet called LW402 in 480 adults with moderate-to-severe atopic dermatitis (eczema). Participants will take either the drug or a placebo daily for 16 weeks. The goal is to see if LW402 can significantly improve eczema severity and skin clearance …

This study compares two prescription ointments, crisaborole and tacrolimus, for treating mild to moderate eczema (atopic dermatitis) in people aged 5 to 25. Researchers will measure how much the skin improves after treatment with each ointment. The goal is to find out which one w…

This study compares a new emollient balm made from seawater (Relipid+) to a leading balm (Lipikar) for mild to moderate eczema in people aged 6 months to 70 years. The goal is to see if the new balm works just as well at reducing symptoms and improving skin health. Researchers wi…

This study tests an experimental capsule called QLS12010 in 160 adults with moderate-to-severe atopic dermatitis (eczema). The goal is to see if it reduces skin redness, itching, and rash better than a placebo over 16 weeks. Participants must have had eczema for at least one year…

This study tests whether child life services—special support to help kids cope with medical procedures—can reduce pain and fear during skin prick allergy tests. About 140 children aged 1-18 will either receive this extra support or standard care. Researchers will measure pain, ho…

This study tests whether adding URGO FilmoCream Eczema to standard steroid cream works better than steroid cream alone for treating atopic dermatitis. Researchers will compare two similar eczema lesions on each of 44 adults—one treated with steroids only, the other with steroids …

This study compares two ways to treat moderate to severe allergic rhinitis: using a nasal steroid spray plus an antihistamine nasal spray versus the same steroid spray plus an antihistamine pill. Fifty people aged 12 to 75 will be randomly assigned to one of the two treatments fo…

This study tests whether giving extra booster shots of allergy medicine directly into the tonsils can better control hay fever symptoms. About 276 adults with allergic rhinitis will receive either the standard three doses or additional boosters. Researchers will track symptom rel…

This study looks at whether applying moisturizer while still in the shower or bath is better than applying it after towel drying for teens with eczema. Thirty participants aged 12-18 will try each method for one month and report which they prefer. Researchers will also measure sk…

This study looks at how well a saltwater (saline) nasal spray works and how safe it is for infants and toddlers aged 3 months to 4 years with stuffy noses from colds, flu, or allergies. About 83 children will use the spray for up to 14 days, and parents will report symptom change…

This study tests two special formulas—amino acid formula (AAF) and extensively hydrolyzed formula (eHF)—in 360 infants aged 0-6 months with suspected cow's milk protein allergy. Babies will receive one formula for at least 2 weeks, and doctors will check if symptoms like diarrhea…

This study tests an injection called GR1802, given alongside usual allergy treatments, to see if it can better control symptoms like sneezing, runny nose, and itchy eyes in people with seasonal allergic rhinitis (hay fever). About 144 adults who have had poor symptom control with…

This study tests whether a natural nasal spray (Puressentiel Allergy Protection) can reduce symptoms of dust mite allergies. Twenty adults with dust mite allergic rhinitis will receive either the spray or a saline placebo before a nasal allergen challenge. Researchers will measur…

This small Phase 2 trial tests whether a single dose of zafirlukast, an asthma drug, can prevent nasal symptoms caused by cat dander. Twelve adults with cat allergies will receive either the drug or a placebo before being exposed to cat dander in a controlled setting. Their sympt…

This study tests whether letting patients report their symptoms online can help doctors schedule follow-up visits only when needed. About 250 adults with chronic skin conditions like eczema or psoriasis will either get standard fixed appointments or flexible scheduling based on m…

This study tests whether people with fibrotic interstitial lung disease can use home monitoring devices—like a spirometer, pulse oximeter, and scale—to help detect serious lung events such as flare-ups or hospitalizations. About 200 participants will use these devices connected t…

This study aims to develop a blood test that measures B regulatory cells, which may indicate whether allergen immunotherapy (allergy shots) is successfully reducing allergic reactions. Researchers will study 80 adults with pollen or venom allergies who are starting routine allerg…

This study will test 35 people with known or suspected allergies to cannabis, tree nuts, or seeds to see if they are also allergic to hemp seeds. Participants will receive skin prick tests and blood tests to measure allergic reactions. The goal is to understand the potential alle…

This study looks at whether changing how much salt you eat can affect skin sodium levels and the severity of eczema or psoriasis. Fifty adults will follow a low-salt diet and take either sodium tablets or a placebo for several weeks. The goal is to see if this approach is practic…

This study tests a tiny microdevice, about the size of a grain of rice, that holds up to 20 different FDA-approved skin medications. Placed directly on the skin, it releases very small amounts of each drug to see how the skin reacts. The goal is to find out if this device can saf…

This study tests whether a skin test can predict allergic reactions to the chemotherapy drug oxaliplatin. About 380 cancer patients will receive a tiny amount of oxaliplatin under the skin before their regular treatment. Researchers will check if the skin test results match who a…

This study looks at how often people develop allergic skin reactions to two different wound dressings used after open shoulder surgery: one made from silk protein and another from a medical glue mesh. About 350 adults having shoulder surgery will be randomly assigned to one dress…

This study monitors 1,500 adults with breast cancer who receive LUMISIGHT during lumpectomy surgery. Researchers will track how often serious allergic reactions occur within 60 minutes of injection. No new drug is being tested; the goal is to better understand the safety of this …

This study in Côte d'Ivoire tests whether giving mothers a cash reward for breastfeeding until their child is 24 months old increases breastfeeding rates and improves child and maternal health. About 1,040 mothers will either receive the cash incentive or just educational materia…

This study looks at whether premature infants who had necrotizing enterocolitis (NEC) are more likely to develop allergies by age 2. Researchers will compare skin prick test results between 130 infants with and without NEC. The goal is to understand if NEC affects later allergy d…

This study is testing a new, non-invasive way to collect and analyze skin oil (sebum) using a simple adhesive patch called Sebutape. Researchers will recruit 200 people, including healthy volunteers and patients with acne, eczema, psoriasis, or seborrheic dermatitis. The goal is …

This study will follow 50 Costa Rican patients with moderate-to-severe atopic dermatitis (eczema) who are receiving advanced treatments like dupilumab or JAK inhibitors as part of their regular care. Researchers will collect information on patient characteristics, treatment patte…

This study looks at how different ways of processing soy (like heating or fermenting) change its ability to cause allergic reactions. Researchers will test processed soy in the lab and then on the skin of 55 adults with soy allergy. The goal is to understand which processing meth…

This study tests a new program designed to help middle school students (ages 11-13) develop a sense of responsibility toward climate change. The program is based on two well-known theories about how people form beliefs and make decisions. Researchers will measure changes in stude…

This study will take high-resolution photos of the eyes of 950 people with psoriasis, eczema, or hives, plus healthy volunteers. Using artificial intelligence, researchers aim to find eye patterns linked to these skin conditions. The goal is to create a noninvasive tool for earli…

Human seminal plasma allergy is a rare condition causing pain and inflammation after unprotected sex, but its impact on quality of life is poorly understood. This study will enroll 20 women treated at Angers University Hospital to compare standard quality-of-life questionnaires a…

This study follows 100 adults who had an allergic reaction to contrast media (dye used in CT scans and other imaging) to see if the allergy persists over time. Participants will undergo repeat skin testing to check for ongoing sensitivity. The goal is to understand how long the a…

This study will test a new, gentle device that collects fluid from the skin of babies up to 6 months old. Researchers want to see if it's comfortable and can measure chemical signals that may explain why some babies get eczema. By comparing healthy babies and those with eczema, t…

This study will create a registry of 200 adults who have had immediate allergic reactions to drugs, like hives or anaphylaxis within an hour of taking medication. Researchers will analyze blood samples and medical records to better understand the causes of these reactions. The go…

This study looks at how caring for a child with mild to moderate eczema (atopic dermatitis) affects caregivers' work and family life. About 100 Canadian caregivers will answer questionnaires about missed work, reduced productivity, and family impact. The goal is to better underst…

This study will collect existing medical records from about 20,000 people aged 12 and older in Italy who have one of five inflammatory skin conditions: psoriasis, atopic dermatitis, vitiligo, alopecia areata, or hidradenitis suppurativa. Researchers want to describe who gets thes…

This study will use a special headband that reads brain waves to see how adults with mild to moderate atopic dermatitis (eczema) respond to a single application of a marketed cream compared to plain water. Twenty participants will have their brain activity measured for signals re…

This study uses artificial intelligence to understand how air pollution and climate change impact respiratory diseases like allergic rhinitis and asthma. Researchers will gather health data from about 1,900 patients across Europe and analyze it with AI tools to find better ways t…

This study aims to find biomarkers—signs in the body—that can tell if a child will have an allergic reaction to peanut during a feeding test. It will involve 500 children aged 1 to 17 who are suspected of having a peanut allergy. No treatment is given; the goal is to better under…

This study compares two oral formulations of pranlukast, a drug used for asthma and allergic rhinitis, to see if they are equivalent. Sixty healthy adults will receive a single dose of each version in random order under fasting conditions. The main goal is to measure drug levels …

Healthspan Connect is a new research programme aiming to understand what helps people stay healthy as they age. It will recruit 100,000 participants aged 12 and older across the UK, using digital tools and home-based sample collection. The study will explore how lifestyle, enviro…

This study examines immune cells in 60 people with allergic conjunctivitis, both those receiving desensitization therapy and those not, plus healthy controls. Researchers will analyze blood and tear samples to measure specific immune markers and cell activity. The goal is to find…

This study looks at whether biologic therapy can reverse long-term lung damage in adults with severe asthma. Researchers will follow 150 patients and 50 healthy volunteers for two years, using advanced imaging and lung function tests. The goal is to see if treatment leads to 'cli…