Modified pork could revolutionize Alpha-Gal allergy testing

NCT ID NCT07611435

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether specially modified pork (alpha-gal knockout) causes fewer allergic reactions than regular pork in people with alpha-gal syndrome. Each of the 160 participants will eat both types of pork on different days to see which one is safer for diagnosis. The goal is to improve how doctors confirm this red meat allergy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

alpha-gal knockout pork and wild-type pork

What this could lead to

If successful, this could provide a safer and more accurate way to diagnose alpha-gal syndrome using a specially modified pork product.

What could go wrong

This is a Phase 2 trial with only 160 participants, so results may not apply to everyone. The modified pork may still cause reactions in some people.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

allergic disease alpha-gal syndrome red meat allergy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Arkansas Children's Hospital Research Institute: Department of Pediatrics, Allergy & Immunology

    Little Rock, Arkansas, 72202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • North Carolina Children's Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Virginia Health System: Division of Asthma & Immunology

    Charlottesville, Virginia, 22908, United States

    Contact

  • Vanderbilt University Medical Center: Division of Pediatric Allergy, Immunology, and Pulmonary Medicine

    Nashville, Tennessee, 37232, United States