Modified pork could revolutionize Alpha-Gal allergy testing
NCT ID NCT07611435
First seen Jun 24, 2026 · Last updated Jul 07, 2026 · Updated 3 times
Summary
This study tests whether specially modified pork (alpha-gal knockout) causes fewer allergic reactions than regular pork in people with alpha-gal syndrome. Each of the 160 participants will eat both types of pork on different days to see which one is safer for diagnosis. The goal is to improve how doctors confirm this red meat allergy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- alpha-gal knockout pork and wild-type pork
- What this could lead to
- If successful, this could provide a safer and more accurate way to diagnose alpha-gal syndrome using a specially modified pork product.
- What could go wrong
- This is a Phase 2 trial with only 160 participants, so results may not apply to everyone. The modified pork may still cause reactions in some people.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Arkansas Children's Hospital Research Institute: Department of Pediatrics, Allergy & Immunology
Little Rock, Arkansas, 72202, United States
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North Carolina Children's Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology
Chapel Hill, North Carolina, 27599, United States
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University of Virginia Health System: Division of Asthma & Immunology
Charlottesville, Virginia, 22908, United States
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Vanderbilt University Medical Center: Division of Pediatric Allergy, Immunology, and Pulmonary Medicine
Nashville, Tennessee, 37232, United States
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