New cream targets itch in eczema patients

NCT ID NCT07560618

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a cream called roflumilast 0.15% for itching in people with mild to moderate atopic dermatitis (eczema). About 40 participants aged 12 and older will apply the cream once daily for 4 weeks. Researchers will track how patients describe their itch and other skin sensations using a smartphone app, and measure changes in itch severity over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Roflumilast 0.15% cream

What this could lead to

If successful, this could provide a new topical option to ease itching in atopic dermatitis and help doctors better understand how patients describe their skin sensations.

What could go wrong

This is a small, early-phase study with only 40 participants and no placebo group, so results may not apply broadly. The cream may not work for everyone or could cause skin irritation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema Mitchell syndrome Pruritus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Integrative Skin Science and Research

    Sacramento, California, 95815, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact