Don't wash that baby! study tests if keeping vernix on prevents eczema

NCT ID NCT07333378

Not yet recruiting Prevention Sponsor: Pontificia Universidad Catolica de Chile Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This study tests whether leaving the white, creamy coating (vernix caseosa) on a newborn's skin for at least 24 hours after birth can prevent eczema (atopic dermatitis) during the first year of life. Over 1,300 mother-infant pairs in Chile will be randomly assigned to either keep the vernix on or have it washed off as usual. Researchers will track how many babies develop eczema and measure skin health and microbiome differences.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: vernix caseosa (the natural white coating on newborns)
What this could lead to: If it works, this simple, no-cost change in newborn care could reduce eczema risk in infants worldwide.
What could go wrong: This is a single study in Chile; results may not apply everywhere. The intervention is subtle, so the effect may be small or hard to detect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cellulitis Eczema staphylococcal infection atopic eczema prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

Clínica San Carlos de Apoquindo

Las Condes, RM, Chile
Hospital Clínico Universidad Católica

Santiago, RM, Chile

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