Pontificia Universidad Catolica De Chile

This study tests whether adding tiny algae that produce oxygen to a skin-regeneration bandage helps deep wounds heal better and faster. Twenty adults with full-thickness skin wounds will receive either the standard bandage or the algae-enhanced version. Researchers will measure h…

This study tests whether taking a daily oil rich in linoleic acid (a type of omega-6 fat) can improve insulin resistance and other metabolic health markers in adults. 120 participants with insulin resistance will receive either the linoleic acid oil or a control oil for 8 weeks. …

This study tests whether keeping patients with severe lung failure (ARDS) lying on their stomach for more than 48 hours straight helps them survive better than the usual 16-24 hour daily sessions. About 780 adults on breathing machines will be randomly assigned to one of the two …

This study tests whether giving tuberculosis (TB) preventive medicine right away to children and teens who live with a TB patient can stop them from getting infected. About 647 kids aged 5 to 17 will be split into two groups: one gets the medicine immediately, the other gets stan…

This study tests an AI system that helps doctors manage pain during surgery. It monitors patients in real time to give the right amount of opioid painkiller, avoiding too much or too little. The goal is to improve patient comfort and reduce side effects. About 150 adults having p…

This study tests whether a personalized, algorithm-based psychotherapy is more effective than usual one-on-one therapy for adults with major depression complicated by personality problems or past trauma. About 150 people in Chile's public mental health system will be randomly ass…

This study tests a medical device called PIMUN to see if it can reduce the time preterm babies spend with low oxygen levels. About 20 infants born before 34 weeks and diagnosed with apnea of prematurity will take part. Each baby will be monitored for 48 hours with the device and …

This study looks at how changing the pressure in a breathing machine (ventilator) affects the effort patients need to breathe on their own. It will include 12 adults in the ICU who are already using a ventilator to help them breathe. Researchers will test four different pressure …

This study tests whether using a virtual reality headset during exercise can reduce the effort needed to breathe. Ten healthy adults will cycle with and without VR to compare breathing effort, anxiety, and comfort. The goal is to see if VR can be a simple, non-drug way to help pe…