Pontificia Universidad Catolica De Chile

This study tests whether leaving the white, creamy coating (vernix caseosa) on a newborn's skin after birth can prevent eczema (atopic dermatitis) in the first year of life. About 1,383 babies will be randomly assigned to either keep the vernix or have it removed as usual. Resear…

This study tests whether a numbing injection (retrolaminar block) given before lumbar spine fusion surgery can lower the amount of strong painkillers (opioids) needed afterward. About 44 adults will be randomly assigned to receive either the real block or a fake one. The main goa…

This study tests whether a high-dose anesthetic cream can reduce chronic nerve pain in adults aged 60 and older who haven't gotten relief from other treatments. Thirty participants will apply either the active cream or a placebo daily for two weeks, then switch. Researchers will …

This study looks at how the steroid dexamethasone affects levels of the painkiller bupivacaine in the blood when given with a nerve block for shoulder surgery. Forty adults will receive the nerve block with dexamethasone either near the nerve or through a vein. Blood samples will…

This study tests whether an artificial intelligence (AI) app can improve follow-up for patients who receive continuous pain relief after surgery. About 166 adults will use either the AI app or a standard automated messaging app. The goal is to see if the AI app reduces the number…

This study aims to find out how many people experience long-term pain after bunion (hallux valgus) surgery and what factors might increase that risk. Researchers will review medical records and ask 350 adults who had surgery between 2021 and 2024 to fill out pain and risk questio…