Tiny study hopes to Fine-Tune ventilator settings for easier breathing
NCT ID NCT07437846
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how changing the pressure inside the lungs (called PEEP) affects how hard patients have to work to breathe while on a ventilator. Twelve adults in the ICU who are already breathing with some help from a machine will have their PEEP set to four different levels in random order. Researchers will measure breathing effort using a small balloon in the esophagus and other non-invasive methods. The goal is to understand which PEEP level reduces strain on the breathing muscles, which could help prevent lung injury.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Positive end-expiratory pressure (PEEP) level adjustment
What this could lead to
If successful, this could help doctors choose better ventilator settings to reduce lung injury in patients with respiratory failure.
What could go wrong
This is a very small, early-stage physiological study with only 12 participants. It measures short-term effects and may not translate into better patient outcomes or generalizable guidelines.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Phone: •••-•••-•••• Email: •••••@•••••
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Phone: •••-•••-••••
Locations
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Hospital Clinico UC
RECRUITINGSantiago, Santiago Metropolitan, Chile
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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