Could a Custom-Tailored therapy beat standard talk therapy for tough depression?

NCT ID NCT07380451

Recruiting now Symptom relief Sponsor: Pontificia Universidad Catolica de Chile Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new type of talk therapy that is personalized for each person's emotional, relationship, and self-image struggles. It is for adults with depression that also involves personality problems or past trauma. 150 people in Chile's public health system will get either this modular therapy or usual one-on-one therapy. The goal is to see if the personalized approach leads to more people feeling better and staying well.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Modular Intervention for Depression Therapy (MIND Therapy) - a personalized psychotherapy
What this could lead to: If successful, this could provide a more effective, personalized therapy option for depression complicated by personality issues or trauma, especially in public health settings.
What could go wrong: This is a small pilot study (150 people) in one country's public system, so results may not apply broadly. The therapy is complex and may not outperform usual care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSION

Contacts and locations

Locations

CDT CASR
RECRUITING

Santiago, Chile
COSAM La Bandera
ACTIVE_NOT_RECRUITING

Santiago, Chile
COSAM La Granja
RECRUITING

Santiago, Chile
COSAM La Pintana
RECRUITING

Santiago, Chile
COSAM Rinconada
RECRUITING

Santiago, Chile

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