New nerve block aims to slash opioid use after spine fusion

NCT ID NCT07291388

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an ultrasound-guided retrolaminar block (a numbing injection near the spine) can lower the amount of opioids patients need after lumbar spine fusion surgery. Forty-four adults will be randomly assigned to receive either the active block or a sham injection, and all will get standard pain medicines. Researchers will track opioid use, pain scores, and recovery quality for three days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

retrolaminar block with bupivacaine and epinephrine

What this could lead to

If it works, this could offer a way to reduce opioid use and improve pain control after spine surgery.

What could go wrong

This is a small, early-stage trial with only 44 participants. The sham group may also show benefits, and results may not apply to all spine surgeries.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute Pain ankylosis lumbar disk disease vertebral column disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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  • Contact

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