Your genes may hold the key to predicting Post-Surgical pain

NCT ID NCT02383342

Ongoing Knowledge-focused Sponsor: Radboud University Medical Center Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study aims to find out whether a person's genes and clinical profile can predict who will develop acute or chronic pain after major surgery. Researchers will follow 10,000 patients for one year after their operation, tracking pain levels and daily functioning. The goal is to identify biomarkers that could help doctors personalize pain treatment early, potentially preventing long-term suffering.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple test or checklist to predict a patient's risk of chronic pain after surgery, allowing doctors to personalize pain treatment early.
What could go wrong: This is an observational study, so it cannot prove cause and effect. The genetic findings may be complex and require years of further research before they can be used in everyday care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Acute Pain Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PAIN CHRONIC PAIN

Contacts and locations

Locations

Radboudumc

Nijmegen, 6500HB, Netherlands

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