Could inhaled stem cell particles ease allergies and asthma?

NCT ID NCT07453771

Not yet recruiting Disease control Sponsor: The Affiliated Hospital of Qingdao University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing whether inhaling tiny particles from stem cells (called small extracellular vesicles) can safely help people with both allergic rhinitis and asthma. About 18 adults will receive either the active treatment or a placebo via nebulizer daily for two weeks. Researchers will monitor symptoms, lung function, and side effects for up to 24 weeks to see if the approach is promising.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: stem cell-derived small extracellular vesicles (hUC-MSC-sEV-002)
What this could lead to: If it works, this could point toward a new way to control allergic rhinitis and asthma symptoms with a simple inhaled treatment.
What could go wrong: This is a very early, small trial (only 18 people) testing safety and dosing. It may not show clear benefit, and the treatment could cause side effects or fail to work in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

allergic rhinitis asthma Rhinitis, Allergic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALLERGIC RHINITIS ASTHMA

Contacts and locations

Locations

Chongqing General Hospital

Chongqing, 401121, China
The Affiliated Hospital of Qingdao University

Qingdao, Shandong, 266100, China
The First Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, 510080, China
The Second Affiliated Hospital of Shandong First Medical University

Tai’an, Shandong, 271000, China
The Third Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, 510630, China

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