New eczema pill shows promise in Mid-Stage trial

NCT ID NCT07643766

Recruiting now Disease control Sponsor: Enveda Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study tests an experimental pill called ENV-294 for adults with moderate-to-severe atopic dermatitis (eczema). About 200 participants will take either one of three doses of ENV-294 or a placebo daily for 12 weeks. Researchers will measure changes in eczema severity, symptoms, and safety to see if the drug can help control the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ENV-294
What this could lead to: If it works, this could lead to a new daily pill that controls eczema symptoms like itching and redness.
What could go wrong: This is an early phase 2 trial with only 200 people, so it may not show clear benefit. Side effects are still being studied, and the drug may not work better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

Enveda Investigative Site
RECRUITING

Encinitas, California, 92024, United States
Enveda Investigative Site
RECRUITING

Los Angeles, California, 90045, United States
Enveda Investigative Site
RECRUITING

Northridge, California, 91325, United States
Enveda Investigative Site
RECRUITING

Boca Raton, Florida, 33486, United States
Enveda Investigative Site
RECRUITING

Indianapolis, Indiana, 46250, United States
Enveda Investigative Site
RECRUITING

Plainfield, Indiana, 46168, United States
Enveda Investigative Site
RECRUITING

Dallas, Texas, 75230, United States
Enveda Investigative Site
RECRUITING

San Antonio, Texas, 78213, United States
Enveda Investigative Site
RECRUITING

Sugar Land, Texas, 77479, United States

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