New eczema pill shows promise in early trial
NCT ID NCT07465120
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests an experimental drug called CMS-D001 in 160 adults with moderate to severe atopic dermatitis (eczema) that hasn't responded well to creams. Participants will take one of three doses of the drug or a placebo daily for several weeks. The main goal is to see if the drug can reduce eczema severity by at least 75%.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CMS-D001 (an experimental oral drug)
- What this could lead to
- If successful, this could lead to a new daily pill option for people with moderate to severe eczema that is not well controlled by creams.
- What could go wrong
- This is an early Phase 2 study with only 160 people, so results may not hold up in larger trials. The drug is new and side effects are not yet fully known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Affiliated Central Hospital of Shenyang Medical College
Shenyang, Liaoning, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Affiliated Hospital of Binzhou Medical University
Binzhou, Shandong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Affiliated Hospital of Jiangsu University
Zhenjiang, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Affiliated Hospital of North China University of Science and Technology
Tangshan, Hebei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beijing Huairou Hospital
Beijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beijing Tongren Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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China-Japan Friendship Hospital
Beijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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General Hospital of Ningxia Medical University
Yinchuan, Ningxia, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hainan Provincial Fifth People's Hospital
Haikou, Hainan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hangzhou No.1 People's Hospital
Hangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hangzhou Third People's Hospital
Hangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hebei Medical University Second Hospital
Shijiazhuang, Hebei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Peking University Shenzhen Hospital
Shenzhen, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Qilu Hospital of Shandong University
Jinan, Shandong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shaanxi Provincial People's Hospital
Xi'an, Shaanxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanghai Dermatology Hospital
Shanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shenyang Hospital of Integrated Traditional Chinese and Western Medicine
Shenyang, Liaoning, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shiyan People's Hospital
Shiyan, Hubei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sichuan Provincial People's Hospital
Chengdu, Sichuan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Southern Medical University Dermatology Hospital
Guangzhou, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Suzhou Municipal Hospital
Suzhou, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tianjin Medical University General Hospital
Tianjin, Tianjin Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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West China Hospital of Sichuan University
Chengdu, Sichuan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wuhan No.1 Hospital
Wuhan, Hubei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Shanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhengzhou Central Hospital
Zhengzhou, Henan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Other studies related to the condition(s) this trial covers.
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