DIABETES MELLITUS, TYPE 2

This study tested whether personalized, automatic coaching messages based on continuous glucose monitor readings and mood can improve blood sugar control in adults with insulin-treated type 2 diabetes. 46 participants received these messages over 12 weeks. The goal was to see if …

This study tested a new fast-acting insulin (faster aspart) against a standard insulin (NovoRapid) in 331 adults with type 1 or type 2 diabetes. Both groups also took long-acting insulin (degludec) and could use metformin. The goal was to see if the new insulin works better at co…

This study tested a 6-month program that taught nutrition and exercise to 50 mothers and their children (ages 7-12) in the Yaqui Valley, Mexico. The goal was to improve lifestyle habits and reduce risk factors for heart disease and type 2 diabetes. Researchers measured weight, bl…

This study tested an automated insulin delivery system (a smart pump) in 15 adults with type 1 or type 2 diabetes who also had advanced kidney disease or were on dialysis. Participants used the system for 8 weeks, then switched to their usual care for another 8 weeks. The goal wa…

This study looked at how well Xultophy® (a combination insulin and GLP-1 medicine) controls blood sugar in adults with type 2 diabetes in Japan. Researchers followed 244 people for about 26 weeks as they used the drug as part of their normal care. The goal was to see changes in b…

This study tested a medicine called tirzepatide in children and teenagers (ages 10 to under 18) with type 2 diabetes that was not well controlled by metformin or insulin. The goal was to see if tirzepatide could safely lower blood sugar levels better than a placebo. The study las…

This study tested whether simple foot exercises can improve blood flow in the legs of people with type 2 diabetes. 44 adults with diabetes for at least 5 years did either foot exercises or regular activity for 3 months. Those who did the foot exercises had better blood flow in th…

This study tested a once-weekly insulin shot (icodec) combined with a flash glucose monitor (a small sensor worn on the arm) in 51 adults with type 2 diabetes who had never used insulin before. The goal was to see if this approach helps control blood sugar over 26 weeks. Particip…

This study checked the long-term safety of Ozempic in over 3,200 Japanese adults with type 2 diabetes. Participants took the drug as prescribed by their doctor for about 3 years. Researchers tracked side effects, blood sugar control, weight changes, and quality of life. The goal …

This study looked at how quickly a fast-acting insulin (faster aspart) enters the blood in 23 Chinese adults with type 1 or type 2 diabetes. Participants received one injection of the test insulin and one of the standard insulin NovoRapid, in random order. Blood samples were take…

This study looked at whether lotus seed capsules can improve health in people with type 2 diabetes who have nerve damage (diabetic neuropathy). Sixty adults took either a standard diabetes treatment plus a placebo or the same treatment plus lotus seed capsules for 3 months. Resea…

This study tested a program that combines technology (like a home monitoring system) with diabetes education and skills training. It was designed specifically for African Americans with poorly controlled type 2 diabetes. The goal was to see if this approach helps lower blood suga…

This study followed 291 adults with type 2 diabetes whose blood sugar was not well controlled on their current medication (DPP4i). Participants switched to an oral version of semaglutide, a drug that helps lower blood sugar and may aid weight loss. Over about 5-6 months, research…

This study tested a once-weekly injection of semaglutide (2.4 mg) to help people with overweight or obesity lose weight. About 375 adults took part, some receiving the drug and others a placebo, along with lifestyle advice. The main goal was to see how much weight they lost over …

This study tested whether using mobile health tools—like activity trackers that buzz when you sit too long and text message reminders—can help people with type 2 diabetes sit less during work hours. 46 adults with type 2 diabetes who had desk jobs took part. The goal was to see i…

This study tested a new insulin called icodec that is injected just once a week, compared to standard daily insulins, in over 1000 adults with type 2 diabetes. The goal was to see if the weekly insulin controls blood sugar just as well as daily shots. Participants used a special …

This study tested a nutritional drink called Resource Diabet Plus in 59 adults with type 2 diabetes who were malnourished or at risk. Researchers looked at whether the drink helped improve blood sugar and cholesterol levels over 24 weeks. The goal was to see if it works in real-w…

This study tested a mobile app and fitness trackers to give personalized diet and activity advice to 27 adults with type 2 diabetes or prediabetes. The goal was to see if the app could help people improve their blood sugar levels and make healthier choices. The approach uses mach…

This study tested a patient portal tool called My Diabetes Care (MDC) to see if it helps people with type 2 diabetes better control their blood sugar, weight, and cholesterol. About 458 adults from two hospitals took part. The tool gave them easy access to their health informatio…

This study tested whether helping people with type 2 diabetes and on Medicaid get their basic needs met—like food, housing, and safety—could improve their blood sugar control. About 473 adults took part, with some getting a special navigation service and others receiving usual ca…

This study tested whether a special health education program that focuses on patient empowerment can help adults with type 2 diabetes better manage their condition. Fifty participants were split into two groups: one received the empowerment-based education, the other standard car…

This study tested whether personalized text messages, tailored by a computer algorithm, can help adults with type 2 diabetes take their daily pills more consistently. 28 participants received either custom or generic texts for 6 months. The goal was to improve medication adherenc…

This study tested three different doses of semaglutide (2 mg, 8 mg, and 16 mg) in 245 adults with type 2 diabetes and overweight who were already taking metformin. The main goals were to see how well each dose controlled blood sugar and body weight over 40 weeks. Participants rec…

This study looked at whether taking probiotics alongside usual diabetes medications can improve blood sugar, cholesterol, and inflammation in adults with type 2 diabetes. 77 participants aged 35-65 took part. The goal was to see if changing gut bacteria with probiotics could help…

This study looked at how well the diabetes pill Rybelsus (oral semaglutide) controls blood sugar in adults with type 2 diabetes in Italy. Researchers tracked 458 people over 8-10 months, measuring changes in blood sugar levels and body weight. The goal was to see how the drug per…

This study tested whether delivering diabetes-friendly food boxes to people's homes, along with easy-to-understand educational materials, could improve health in low-income adults with type 2 diabetes who also face food insecurity. The study enrolled 101 participants in Arkansas.…

This study looked at the safety and effectiveness of Fiasp, a fast-acting mealtime insulin, in 42 adults with type 1 or type 2 diabetes. Participants used Fiasp as their doctor prescribed for about 6 months. The main goal was to track any side effects, including serious ones and …

This study tested a new fast-acting insulin (NNC0471-0119) given through an insulin pump in 65 people with type 2 diabetes. The goal was to see how quickly it works, how long it lasts, and how safe it is compared to a standard insulin (insulin aspart). Participants were adults ag…

This study tested whether using mobile monitoring devices along with nurse support can help people better manage type 2 diabetes and high blood pressure. 220 adults with poorly controlled diabetes and hypertension took part. Researchers measured changes in blood sugar and blood p…

This study looked at how safe and tolerable a weekly injection of semaglutide (Ozempic) is for people with type 2 diabetes in Chile. 104 adults received the medicine for about 24 weeks, with regular blood and urine tests. The goal was to track any side effects and changes in bloo…

This study looked at whether a DASH-style diet (modified for diabetes) combined with lower salt intake can lower blood pressure in adults with type 2 diabetes and high blood pressure. 105 participants were fed different diets for 5-week periods. The main goal was to see if the DA…

This study tested whether adding pioglitazone or dapagliflozin to standard diabetes pills (alogliptin and metformin) helps control blood sugar better in people with type 2 diabetes. About 133 adults with poorly controlled diabetes took one of the two combinations for 26 weeks. Th…

This study followed 155 adults with type 2 diabetes in Israel who were already prescribed oral semaglutide (Rybelsus) by their doctor. Researchers tracked changes in blood sugar levels and body weight over 8-10 months. The goal was to see how well the medication works in real-wor…

This study looked at whether adding oral diabetes medications (metformin and pioglitazone, or sitagliptin) to a short course of insulin pump therapy could help newly diagnosed type 2 diabetes patients control their blood sugar and achieve remission for up to one year. A total of …

This study tested whether providing medically tailored meals and nutrition counseling through video visits can help people with poorly controlled type 2 diabetes lower their blood sugar. About 600 adults with high A1C levels took part. The goal was to see if these services improv…

This study tested a high dose (7.2 mg) of semaglutide, a once-weekly injection, in 512 adults with obesity and type 2 diabetes. Participants received either the high dose, a lower dose, or a placebo, along with lifestyle counseling. The main goals were to measure weight loss and …

This study tested a new investigational medicine called CagriSema, which combines two drugs (cagrilintide and semaglutide), to see how it affects insulin sensitivity and pancreatic function in adults with type 2 diabetes. 158 participants received either CagriSema, one of the ind…

This small study tested a new artificial intelligence system that automatically controls blood sugar levels in people with type 2 diabetes. Three adults who use insulin at home had their blood sugar managed by the AI system for 24 hours while eating three standard meals. The goal…

This completed study tested a year-long community program for 98 people with type 2 diabetes. Participants received education, dietary advice, therapy, and help with social and financial needs. The goal was to see if this support improved blood sugar levels, weight, and blood pre…

This study tested a smartphone program that uses artificial intelligence and game-like features to help people with type 2 diabetes manage their blood sugar. 88 adults took part for 6 months. The goal was to see if the program was easy to use and could help lower A1C levels, espe…

This study tested a new medicine (NNC0480-0389) combined with semaglutide, an already approved diabetes drug, in 500 adults with type 2 diabetes. The goal was to see how well different doses lower blood sugar over 34 weeks. Participants gave themselves weekly injections and had r…

This study tested whether providing free, ready-to-eat meals designed for diabetes (plus phone coaching) for 6 months could improve blood sugar control in adults with type 2 diabetes who also face food insecurity. 215 participants were randomly assigned to receive the meals or us…

This study tested whether taking a probiotic supplement for 6 weeks could improve blood vessel function and reduce inflammation in 215 adults with heart disease or type 2 diabetes. Researchers measured blood markers and gut bacteria to see if changing gut health might lower heart…

This study tested a remote program that combines digital tools with a 12-week very low-calorie diet (800 calories per day) to help adults with type 2 diabetes lose weight and possibly achieve remission. 100 participants were randomly assigned to either the program or standard car…

This study tested a program that brings together diabetes care, continuous glucose monitoring, and support for social needs like food and housing. It involved 65 adults with type 2 diabetes and high blood sugar levels. The goal was to see if this approach helps patients manage th…

This study tested whether a health behavior program designed with input from immigrant communities can improve diabetes care compared to standard treatment. Researchers enrolled 202 first-generation immigrants with type 2 diabetes and poor blood sugar control. The program focused…

This study looked at how well the diabetes pill Rybelsus (oral semaglutide) works in real life for adults with type 2 diabetes in the UK. Over 300 participants took the medication as prescribed by their doctor and completed questionnaires about their treatment. The main goal was …

This early-stage study tested a new medicine, NNC0519-0130, given as a weekly shot. The goal was to check its safety and how it affects body weight and blood sugar in 82 adults with obesity or type 2 diabetes. Participants received either the drug or a placebo for up to 37 weeks.…

This study tested a new insulin called icodec that is injected just once a week, compared to a standard daily insulin (degludec), in 526 adults with type 2 diabetes. The goal was to see if the weekly insulin controls blood sugar as well as the daily one over 26 weeks. Participant…

This study tested whether adding semaglutide (a GLP-1 drug) to a new once-weekly insulin called insulin icodec helps lower blood sugar in people with type 2 diabetes. 148 adults whose blood sugar was not well controlled on daily insulin alone took part. First, everyone received w…

This study followed 50 adults with type 2 diabetes in Finland who were already prescribed oral semaglutide (Rybelsus) by their doctor. Researchers tracked changes in blood sugar (HbA1c) and body weight over 8-10 months. Participants also filled out a questionnaire about how they …

This study looked at whether weight-loss surgery (vertical sleeve gastrectomy) can improve diabetes and kidney health in teens aged 12-21 with type 2 diabetes. Researchers measured how well the pancreas and kidneys worked before and after surgery. The goal was to see if surgery c…

This study tested a new device used during an endoscopy to regenerate the lining of the first part of the small intestine in people with type 2 diabetes. The goal was to see if the procedure is safe and could help improve blood sugar control. Twenty adults with diabetes not well …

This study tested a new once-weekly injection called IcoSema, which combines insulin and semaglutide, against once-weekly insulin alone in 1291 adults with type 2 diabetes. The goal was to see which better controls blood sugar and body weight over 52 weeks. Participants were rand…

This study tested whether a dietary supplement called phosphatidylserine (PS) can improve blood flow and insulin response in people with type 2 diabetes. The supplement works by blocking an enzyme (ADAM17) that may interfere with blood vessel function. Researchers measured leg bl…

This study tested whether giving adults with type 2 diabetes and food insecurity a financial incentive to buy healthy foods could improve their blood sugar control. About 600 participants were split into two groups: one received a healthy food prescription alone, and the other re…

This study tested a new insulin, insulin icodec, that is injected just once a week, against a standard daily insulin (glargine) in 582 adults with type 2 diabetes. Both groups also used mealtime insulin as needed. The goal was to see if the weekly insulin controls blood sugar as …

This study tested a new once-weekly medicine called IcoSema in 679 adults with type 2 diabetes whose blood sugar was not well controlled with daily insulin. IcoSema combines two drugs to lower blood sugar and may also help with weight loss. Participants received either IcoSema on…

This study looked at three ways to help older adults (65+) with type 2 diabetes: a home exercise program, a plant-based Mediterranean diet, or a diabetes pill called empagliflozin. After 10 weeks, those on the diet or pill also started exercising. The goal was to see which approa…

This study tested whether colostrum supplements (from cow's milk) can improve physical performance, thinking skills, and blood sugar control in people with type 2 diabetes. 80 participants, including healthy volunteers and those with diabetes, took either colostrum or a placebo d…

This study followed 145 adults with type 2 diabetes who were already prescribed the daily pill Rybelsus (oral semaglutide) by their own doctor. Researchers tracked changes in blood sugar (HbA1c) and body weight over 8-10 months, using questionnaires and routine clinic visits. The…

This study tested a smart system that helps people with type 2 diabetes decide how much insulin to take. 140 adults starting insulin therapy used the system or received standard care. The goal was to see if the system improved blood sugar levels safely without increasing dangerou…

This study followed 650 adults with type 2 diabetes in Japan who were already prescribed the daily pill Rybelsus (oral semaglutide). Researchers tracked changes in blood sugar levels, body weight, and any side effects over 8-10 months. The goal was to see how well the medication …

This study tested whether combining two medicines, cagrilintide and semaglutide, works better than either alone for controlling blood sugar in people with type 2 diabetes. 92 adults received either the combo or a single drug plus a dummy shot for 32 weeks. The goal was to see if …

This study looked at how well the once-daily pill Rybelsus® (oral semaglutide) controls blood sugar and weight in adults with type 2 diabetes during routine care. About 465 participants in Spain were followed for 8-10 months while taking the medication as prescribed by their doct…

This study tested whether adding a weekly semaglutide injection to a reduced dose of insulin glargine works as well as a higher insulin dose alone for controlling blood sugar in people with type 2 diabetes and overweight. About 573 participants were followed for 11 months. The go…

This study looked at how well the diabetes pill Rybelsus (oral semaglutide) controls blood sugar in adults with type 2 diabetes in Saudi Arabia. About 194 participants took the medicine as prescribed by their doctor and filled out a questionnaire. The study lasted 8-10 months and…

This study looked at whether adding dapagliflozin to metformin helps people with severe obesity (BMI 40+) and prediabetes or type 2 diabetes lose more weight than metformin alone. About 160 participants took either the combination or metformin only for up to 12 months. The goal w…

This 16-week study tested whether a low-fat vegan diet can improve insulin sensitivity and blood sugar control in people with type 2 diabetes. Twenty-six adults with type 2 diabetes and a BMI between 26 and 40 participated. They received weekly nutrition classes and one-on-one di…

This study tested a new medicine called AZD5004 in 406 adults with type 2 diabetes to see if it helps control blood sugar better than a placebo or another diabetes drug. Participants had diabetes for at least 6 months and were either on diet/exercise alone or stable doses of metf…

This study tested a new medicine called survodutide (BI 456906) in 755 adults with overweight or obesity and type 2 diabetes. Participants received weekly injections of either the drug or a placebo for about 76 weeks, along with diet and exercise advice. The main goal was to see …

This study looked at whether using a smartphone app called 'Dose Check' together with the insulin Tresiba helps people with type 2 diabetes control their blood sugar. About 179 adults in Saudi Arabia took part for 6 to 7 months. The goal was to see if the app supports correct ins…

This study looked at whether taking a postbiotic capsule every day for 12 weeks can help people with type 2 diabetes control their blood sugar better. About 106 adults aged 18 to 70 with type 2 diabetes and overweight took part. Researchers measured changes in blood sugar, insuli…

This study followed 99 adults with type 2 diabetes who were already prescribed oral semaglutide (Rybelsus) by their doctor. Researchers collected information on how well the drug controlled blood sugar and affected body weight over 8-10 months. Participants filled out questionnai…

This small study tested a prebiotic supplement (Molkosan®) in 12 adults with type 2 diabetes or prediabetes. Participants took 20 ml daily for 12 weeks to see if it improved blood sugar, insulin, and cholesterol levels. The goal was to gather early data for a larger trial.

This study tested a new insulin, icodec, that is injected just once a week, against a standard daily insulin (glargine) in nearly 1,000 adults with type 2 diabetes who had never used insulin before. The goal was to see if the weekly insulin controls blood sugar as well as the dai…

This study checked how safe Lyumjev is for adults with type 2 diabetes in India. 150 people took the drug for 26 weeks, and researchers watched for low blood sugar events. The goal was to see how often side effects happen.

This pilot study tested whether people with type 2 diabetes and early kidney disease can take part in a clinical trial from home. Twelve participants collected their own urine, blood, and blood pressure readings remotely. They took empagliflozin first, and based on their response…

This study tested a web-based version of a diabetes self-management program called eDECIDE for African Americans with type 2 diabetes. The program teaches problem-solving skills to handle daily challenges of living with diabetes. Researchers compared eDECIDE to the traditional in…

This study followed 194 adults with type 2 diabetes who were already prescribed oral semaglutide (Rybelsus) by their doctor. Over 8-10 months, researchers measured changes in blood sugar levels (HbA1c) and body weight using routine clinic visits and questionnaires. The goal was t…

This study tested whether dapagliflozin, a drug used for diabetes, can improve heart structure and be safe in people with kidney failure who are on dialysis. 220 adults on maintenance dialysis (with or without diabetes) received either the drug or a placebo. The goal was to see i…

This study tested whether a new way of making semaglutide works as well as the current version for controlling blood sugar in people with type 2 diabetes. About 388 participants took a weekly injection for 28 weeks. The main goal was to see if the new manufacturing process leads …

This study looked at whether using a continuous glucose monitor along with help from a clinical pharmacist can improve blood sugar control in uninsured Black and Hispanic adults with type 2 diabetes. Twenty participants used the monitor and worked with the pharmacist to adjust th…

This study tested whether eating 3 low-calorie meals per day helps control blood sugar and weight better than eating 5 small meals in people with type 2 diabetes who are overweight or obese. Fifty adults followed one of two diet plans for 11 weeks. Researchers measured blood suga…

This study tested a once-daily pill called Rybelsus against other diabetes pills in over 1,000 adults with type 2 diabetes who were already taking metformin. The goal was to see which pill works better at lowering blood sugar over one year. Participants were randomly assigned to …

This study looked at 34 adults with both type 2 diabetes and binge eating disorder. Participants received talk therapy to address binge eating, and researchers checked if this also helped their diabetes and heart health. The goal was to see if treating binge eating can improve bo…

This study tested whether taking a higher dose (25 mg or 50 mg) of the once-daily diabetes pill semaglutide works better than the standard 14 mg dose. Over 1,600 adults with type 2 diabetes took part, gradually increasing their dose over 68 weeks. The main goals were to see if th…

This study looked at whether taking vitamin D3 and prebiotics (a type of fiber) every day for 6 months could improve heart health in adults with type 2 diabetes. 190 people participated. The researchers measured changes in blood sugar, cholesterol, and gut bacteria. The goal was …

This study looked at whether delivering healthy food to the homes of people with type 2 diabetes who live in rural areas and struggle to afford food can help them manage their condition better. Over 400 adults took part, receiving either standard care alone or standard care plus …

This study tested a new insulin dosing calculator for adults with type 2 diabetes when they are admitted to the hospital. The goal was to see if the calculator could help keep blood sugar levels from getting too high or too low without causing dangerous drops. 38 participants rec…

This study looked at how the diabetes pill Rybelsus (oral semaglutide) works in real-world settings for adults with type 2 diabetes. About 194 participants took the medication as prescribed by their doctor and completed questionnaires over 8-10 months. The main goal was to see if…

This study looked at how safe and effective Xultophy is for adults with type 2 diabetes when used in normal doctor visits. About 750 people took the medicine as their doctor prescribed for 26 weeks. The goal was to track side effects and changes in blood sugar and weight.

This study looked at three different diabetes medicines (empagliflozin with metformin, sitagliptin with metformin, or metformin alone) in 186 adults who were newly diagnosed with type 2 diabetes and overweight. Over 12 weeks, researchers measured changes in blood markers, blood s…

This study looked at how the diabetes pill Rybelsus® works in 187 adults with type 2 diabetes in Mexico. Researchers measured changes in blood sugar and body weight over 8-10 months. Participants took the pill as prescribed by their doctor and filled out questionnaires during reg…

This study tested a virtual health program for African immigrants aged 25-75 who are uninsured and have at least two risk factors like high blood pressure, prediabetes, or obesity. Participants used Bluetooth scales and blood pressure monitors to track their health over six month…

This study tested a new diabetes pill (semaglutide) against a dummy pill in 132 children and teens with type 2 diabetes. Participants took one tablet each morning on an empty stomach and waited 30 minutes before eating. The study lasted about 15 months and checked how well the me…

This study tested two types of exercise in 50 adults with type 2 diabetes over 6 weeks. One group did circuit training (mixing aerobic and resistance exercises), and the other did standard strength training. Researchers measured heart and lung fitness, blood sugar, and quality of…

This study looked at whether adding community health workers to regular care helps patients with type 2 diabetes and high blood pressure in rural Mexico. 168 adults took part. The goal was to see if their blood sugar and blood pressure improved and if they took their daily medici…

This study tested a new medicine, NNC0519-0130, in 299 adults with type 2 diabetes. Participants received weekly injections of different doses to see how well it lowers blood sugar and body weight. The study lasted about 40 weeks and is now complete.

This study looked at how well oral semaglutide works for Thai adults with type 2 diabetes. Researchers reviewed medical records of 209 patients over 6 to 12 months to see changes in blood sugar (HbA1c) and body weight. The goal was to understand real-world effectiveness in a Thai…

This study tested whether using a continuous glucose monitor (CGM) in the hospital can help keep blood sugar levels in a safe range for people with type 1 or high-risk type 2 diabetes. 157 patients wore a wireless CGM that sent real-time glucose readings to a care team, who then …

This study looked at whether semaglutide, a type 2 diabetes medicine taken as a daily tablet, can lower the risk of serious heart problems like heart attack or stroke. Over 9,600 adults with type 2 diabetes and existing heart disease took either semaglutide or a placebo for up to…

This study looked at whether two blood tests, eLIFT and FibroMeter, can accurately detect advanced liver fibrosis (scarring) in people with type 2 diabetes. The researchers compared these blood tests to a liver scan (FibroScan) and, in some cases, a liver biopsy. The goal is to f…

This study tested a diabetes prevention program designed for college students facing challenges like food and financial insecurity. About 80 UCLA undergraduates at high risk for type 2 diabetes took part. The program included 19 group sessions focused on healthy habits and weight…

This study tested a lifestyle program designed for rural families at high risk for heart disease and type 2 diabetes. Over 500 Hispanic and non-Hispanic adults participated, focusing on healthy eating, physical activity, and weight management. The goal was to see if a culturally …

This study looked at whether foot-ankle exercises or walking exercises can help people with type 2 diabetes who have foot nerve problems. 375 adults with diabetes did either foot exercises, walking, or received standard care for 12 weeks. Researchers measured foot sensation, stre…

This early-stage study tested a new medicine called MK-2828 in 46 adults with type 2 diabetes. The main goal was to see if the drug is safe and well-tolerated. Researchers also measured how the drug moves through the body and whether it affects a marker of inflammation (hsCRP). T…

This study tested whether mindfulness-based practices can reduce stress, anxiety, and depression in adults with type 2 diabetes. A total of 140 participants were split into two groups: one received mindfulness training, the other did not. Researchers measured changes using standa…

This study tested whether a 6-month online mindfulness program could help adults with type 1 or type 2 diabetes lower their blood sugar and stress. About 309 people with high stress and uncontrolled diabetes took part. Half received mindfulness training, the other half stress man…

This study looked at how easy and convenient the DuraTouch® device is for people with type 1 or type 2 diabetes. 128 participants used the device for about 12 weeks and rated their satisfaction. The goal was to see if the device makes daily diabetes care simpler and more convenie…

This study tested a single injection of umbilical cord stem cell secretome in 12 men with severe erectile dysfunction that did not improve with sildenafil (Viagra). The goal was to check safety and see if it could improve erection hardness and function. All participants had type …

This study looked at whether intermittent fasting (not eating for certain periods) can improve how well the pancreas makes insulin in people with early type 2 diabetes. 51 adults with diabetes and obesity took part. The goal was to see if fasting could help control blood sugar an…

This study tested whether a special type of lighting could help people with Alzheimer's disease and type 2 diabetes sleep better and improve their health. 61 participants living in assisted living or nursing homes received either the special lighting or a regular light for 8 week…

This study tested whether eating house cricket powder before a meal could lower blood sugar spikes in people with type 2 diabetes. Twenty adults on metformin took cricket powder, whey protein, or a placebo mixed into soup. Their blood sugar and insulin were measured for two hours…

This study looked at whether modified Otago exercises can help people with type 2 diabetes and nerve damage (neuropathy) improve their balance, joint awareness, and overall physical fitness. 38 adults aged 40-65 who were not regularly active took part. The exercises aimed to make…

This study tested whether a smartphone app helps people with type 2 diabetes continue taking their Ozempic injections as prescribed. 304 participants either used the app or received standard care. The study tracked how long they stayed on the medication and if they reached their …

This study tested if using a Fitbit activity tracker along with text message reminders could help Hispanic teenagers with obesity increase their physical activity and improve their sleep. 43 teens aged 14-16 took part. The goal was to see if this simple, technology-based approach…

This study tested whether mindfulness training helps people with type 2 diabetes better manage food cravings and stick to a low-carb diet. Sixty adults with type 2 diabetes who often ate in response to cravings participated. The goal was to see if mindfulness skills could reduce …

This study looked at how high-intensity interval training (HIIT) affects blood sugar control and other health markers in women with type 2 diabetes. Researchers compared premenopausal and postmenopausal women aged 40-65 who did supervised HIIT workouts. The goal was to see if thi…

This study tested whether semaglutide, a diabetes medicine, improves walking ability in people with type 2 diabetes and peripheral artery disease (narrowed leg arteries). About 792 adults received weekly injections of semaglutide or a placebo for 59 weeks. The main goal was to me…

This early-stage study tested a new medicine called NNC0519-0130 in 20 Chinese men who were overweight or had obesity. The goal was to see how the drug moves through the body and if it is safe. Participants received either the drug or a placebo for about 28 weeks, with up to 7 di…

This study looked at whether semaglutide, a diabetes medication, can improve the number and function of certain stem cells that help protect blood vessels in people with type 2 diabetes. Ten adults with diabetes took either semaglutide or a placebo for 24 weeks. Researchers measu…

This study looked at 55 adults with diabetes who have an allergy to insulin. The goal was to create a better way to diagnose this allergy and understand why it happens. Researchers tested skin reactions to insulin and studied the immune system and genetics of participants to find…

This study looked at 202 people with type 2 diabetes and early-stage diabetic eye disease (non-proliferative diabetic retinopathy). Researchers used non-invasive eye scans to find markers that could predict if the disease would get worse or lead to sight-threatening problems. The…

This study looked at whether exercising in the afternoon is better for heart and metabolic health in adults with type 2 diabetes or prediabetes. Researchers measured changes in body weight, blood sugar control, and blood flow. The goal was to see if timing exercise could improve …

This study looked at whether stopping certain diabetes medications (incretin-based therapies) before an upper endoscopy reduces the amount of food or liquid left in the stomach. Having too much stomach content can make the procedure harder or riskier. The study included 69 adults…

This study aims to understand why people of Black African and Caribbean descent have a higher risk of developing type 2 diabetes. Researchers compared how quickly the stomach empties a sugary drink in 56 healthy volunteers—half white European, half Black African/Caribbean. They m…

This study looked at how semaglutide, a diabetes medicine, affects the kidneys in people with type 2 diabetes and chronic kidney disease. About 106 participants received either semaglutide or a placebo injection once a week for a year. Researchers used MRI scans, blood and urine …

This study tested how well a new device called GLUCUBE measures blood sugar in 52 adults with type 2 diabetes. Participants used the system at home and compared its accuracy to a standard finger-stick glucometer. The goal was to see if the device becomes more accurate the longer …

This study looked at over 11,000 people with type 2 diabetes and a certain type of heart failure to see if information from insurance claims could give the same results as a traditional drug trial. The goal was to learn when real-world data can be trusted to answer medical questi…

This study looked at 172 people with and without HIV to understand why those with HIV have a higher risk of diabetes. Researchers examined fat tissue and immune cells to see if chronic immune activation in fat contributes to insulin resistance. The goal was to gather knowledge, n…

This study examined if the type of diabetes medication taken before a cancer diagnosis affects survival and complications after cancer in adults with obesity and type 2 diabetes. Researchers analyzed health records from over 200,000 people, comparing those who used GLP-1 receptor…

This study tested whether helping low-income African Americans with diabetic kidney disease meet their basic needs (like food, housing, and utilities) could improve their health. Fifty participants received support to address these challenges. The goal was to see if this approach…

This study looked at how much of a diabetes self-management class people with type 2 diabetes need to attend to see real benefits. 120 participants were split into groups that completed 100%, 60%, 10%, or no class. Researchers measured changes in self-care, diabetes distress, and…

This study looked at whether viral infections in pregnant women with diabetes might increase the chance of their babies being born with heart defects. Researchers analyzed blood and stool samples from 114 women to detect viruses and immune responses. The goal was to gather initia…

This study looked at 470 adults aged 18-75 with type 2 diabetes and metabolic syndrome to identify patterns used in Traditional Chinese Medicine (TCM). Researchers used a standard questionnaire and four TCM diagnostic methods to classify each person's syndrome. The goal was to be…

This study looked at health insurance records from over 58,000 people with type 2 diabetes and a type of heart failure (HFpEF). The goal was to see if a drug called semaglutide works as well in everyday patients as it did in a previous clinical trial. Researchers compared those t…

This study looked at 67 adults with type 2 diabetes and fatty liver disease who were starting a type of diabetes medication called SGLT2 inhibitors. Researchers used ultrasound and blood tests to measure changes in liver stiffness, fat, and injury markers before and after 6 month…

This study analyzes health records from over 158,000 people with type 2 diabetes to see if injectable semaglutide reduces major heart problems like heart attacks and strokes. Researchers are testing whether real-world data can reliably reproduce results from a previous clinical t…

This study looked at how type 2 diabetes works in children and young adults aged 12 to 25. Some participants took diabetes medicine with or without extra insulin to see if resting the pancreas could help it make more insulin. The study also compared them to healthy volunteers to …

This study followed over 12,000 people from the Gila River Indian Community for decades to understand type 2 diabetes and its complications. Participants received regular check-ups every two years, including glucose tests and physical exams. The goal was to learn how diabetes dev…

This study looked at medical records from over 28,000 people with type 2 diabetes and a specific type of heart failure (HFpEF) to compare two drugs: tirzepatide and semaglutide. The goal was to see which one better reduces the risk of death or hospitalization for heart failure. T…

This study looked at how a drug called LCZ696 (used for heart failure) affects the kidneys and heart in 72 people with type 2 diabetes, some with early signs of heart stiffness and some without. The goal was to understand if this drug can prevent the progression to symptomatic he…

This study tested a new long-acting insulin called insulin icodec in 18 children and teens aged 10 to 17 with type 2 diabetes. Each participant received a single injection based on their body weight and was monitored for about 8 weeks. The goal was to see how the insulin moves th…

This study aimed to find the smallest amount of fatty acids that causes mild insulin resistance in healthy people. Nine volunteers received a fatty acid infusion to see how it affects their body's ability to use insulin. The results will help design future studies on type 2 diabe…

This study looked at whether a new diabetes medicine called NNC0519-0130 changes how the body processes a common birth control pill. It also checked if the drug affects how fast the stomach empties. The study involved 47 healthy women past menopause and lasted about 35 weeks. Res…

This study aimed to understand why some people develop type 2 diabetes by looking at genetic and lifestyle factors. About 1,759 overweight adults aged 18-55 took part in tests measuring how their bodies handle sugar and store energy. The goal was to find genetic markers and early…

This study looked at ways to help more people with type 2 diabetes attend education classes that teach self-management skills. Researchers tested different methods to increase referrals from doctors and used peer support to encourage attendance. The goal was to find the best appr…

This early-stage study looked at how the diabetes drug rongliflozin is processed in people with mild or moderate liver damage compared to healthy people. 32 adults took a single dose, and researchers measured drug levels and side effects. The goal was to gather safety and dosing …

This study looked at a new computer tool designed to help homecare nurses decide which patients need the most urgent care after leaving the hospital. Researchers tested the tool with nearly 2,000 patients who had conditions like diabetes, heart failure, or lung disease. The goal …

This study tested whether an electronic alert in medical records could help doctors refer patients with fatty liver disease (NASH) to liver specialists. It involved 30 doctors from internal medicine, family medicine, and endocrinology. The goal was to see if the alert increased a…

This study looked at how breathing and recovery after a short walk differ between people with type 2 diabetes who use insulin and those who don't. Researchers tested 70 adults with breathing tests and a 6-minute walk. The goal was to see if insulin use is linked to weaker breathi…

This study tested a new way for patients to share their family health history with their doctor using an app. The goal was to see if this helps doctors spot people at higher risk for certain cancers, heart disease, or diabetes. Over 600 adults aged 30-69 took part. The approach i…

This study observed 240 Kazakh adults with newly diagnosed diabetes to understand how their bodies handle insulin and how their immune system reacts early on. Researchers measured blood sugar, insulin resistance, and immune markers to find differences between types of diabetes. T…

This study looked at how different levels of kidney function affect a new medicine called NNC0519-0130 for type 2 diabetes. Thirty-six adults with normal, mildly, moderately, or severely reduced kidney function received a single dose. Researchers measured the drug levels in their…

This study looked at how inherited genes influence the way people respond to two common diabetes medications, metformin and glipizide. Over 1,000 adults at risk for or with type 2 diabetes took part. Researchers measured blood sugar and insulin levels after taking the drugs to se…

This study tested a culturally adapted program called DM-BOOST para Latinx to help Spanish-speaking Latinx adults with type 2 diabetes better manage their condition. The program used behavioral economics and technology to encourage patients to attend diabetes education classes an…