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Which diabetes combo works best? new study pits pioglitazone against dapagliflozin

NCT ID NCT03499704

First seen Mar 25, 2026 · Last updated May 23, 2026 · Updated 8 times

Summary

This study tested whether adding pioglitazone or dapagliflozin to standard diabetes pills (alogliptin and metformin) helps control blood sugar better in people with type 2 diabetes. About 133 adults with poorly controlled diabetes took one of the two combinations for 26 weeks. The main goal was to see if the pioglitazone combo was at least as good as the dapagliflozin combo at lowering HbA1c, a key blood sugar measure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, Gyeonggi-do, 16499, South Korea

  • Chosun University Hospital

    Gwangju, 61453, South Korea

  • Daejeon Eulji Medical Center, Eulji University

    Daejeon, 35233, South Korea

  • Inje University Haeundae Paik Hospital

    Busan, 48108, South Korea

  • Kangbuk Samsung Hospital

    Seoul, 03181, South Korea

  • Korea University Anam Hospital

    Seoul, 02841, South Korea

  • Kyung Hee University Hospital at Gangdong

    Seoul, 05278, South Korea

  • Pusan National University Hospital

    Busan, 49241, South Korea

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • The Catholic University of Korea, Bucheon, St. Marys Hospital

    Bucheon-si, Gyeonggi-do, 14647, South Korea

  • The Catholic University of Korea, ST. Vincents Hospital

    Suwon, Gyeonggi-do, 16247, South Korea

  • Ulsan University Hospital

    Ulsan, 44033, South Korea

  • YeungNam University Hospital

    Daegu, 42415, South Korea

  • Yonsei University Health System Severance Hospital

    Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.