DIABETES MELLITUS, TYPE 2

This study tests an experimental medicine, CagriSema, to see how well it lowers blood sugar in people with type 2 diabetes. About 400 adults aged 18-64 will be randomly assigned to use one of two injection devices. The study lasts about 38 weeks and CagriSema is not yet available…

This early-stage study tests a new drug, AMG 127, to see if it is safe and how the body processes it. The trial involves healthy adults aged 18-65 and people with type 2 diabetes aged 40-75. Researchers will monitor side effects and measure drug levels in the blood.

This study tests a bedside screening program for hospitalized adults with type 2 diabetes who have unmet social needs (like food or housing). After discharge, patients get help navigating resources. The goal is to see if this reduces return trips to the hospital within 90 days co…

This study tests a virtual program called STRIDE for adults aged 21-44 who were recently diagnosed with type 2 diabetes and have children aged 2-14. The program teaches practical skills like self-care, healthy eating, and family physical activity. The goal is to reduce diabetes-r…

This study looks at the safety and effectiveness of Rybelsus, a daily pill for type 2 diabetes, when used in everyday medical practice in Korea. About 600 adults will take the medicine as their doctor prescribes, and researchers will track any side effects and blood sugar changes…

This study looks at whether a common diabetes medication (GLP-1 RA) can improve muscle strength and bone health in women over 65 with type 2 diabetes. Twenty participants will take the drug as part of their regular care and undergo tests like grip strength and bone density scans …

This early-stage study tests a new experimental drug, UI087, against taking three separate diabetes medicines together. It involves 44 healthy adults who will receive a single dose of each treatment on different days to compare safety and how the drug moves through the body. The …

This study tests a 12-week program where people with type 2 diabetes and a family member receive diabetes education and quizzes via WhatsApp. The goal is to see if this approach improves blood sugar control, self-care, and family support compared to usual care. The study involves…

This study looks at the safety and performance of the Endogenex System in 50 adults with type 2 diabetes. Participants previously received a sham (fake) procedure in an earlier study. The goal is to see if the device is safe and works well for managing diabetes.

This study tests an experimental injection called IN-B00009 in adults with type 2 diabetes whose blood sugar is not well managed by diet and exercise alone. About 110 participants will receive either the drug or a placebo for 24 weeks. The main goal is to see if the drug lowers H…

This study looks at how well the drug tirzepatide works for weight loss and blood sugar control in everyday medical practice in Paraguay. It will include 160 adults: 80 with obesity but no diabetes, and 80 with type 2 diabetes (with or without obesity). All participants will take…

This study tests a once-weekly injection called CagriSema (cagrilintide plus semaglutide) in 80 children and teens with type 2 diabetes. The goal is to see if it lowers blood sugar and body weight better than a placebo. The study lasts about 15 months, with all participants recei…

This study looks at whether a 3-month video program about healthy eating and exercise can help adults with type 2 diabetes control their blood sugar better. It compares the program when it is given by a person's own doctor versus a doctor they don't know. The main goal is to see …

This study tests whether a smartphone app that shows real-time blood sugar and activity data can help 100 teens and young adults with type 2 diabetes improve their glucose control. Participants use a continuous glucose monitor, Fitbit, and the Healthmine app for 90 days, then are…

This study tests a new weekly injection, NNC0487-0111, against the approved drug semaglutide in 1000 adults with overweight or obesity and type 2 diabetes. Participants will receive two weekly shots (one active, one placebo) for about a year. The main goal is to see how much weig…

This study will test a special education program designed to boost confidence in managing type 2 diabetes. 400 adults will either take the program or get standard care. The goal is to see if the program helps with blood sugar monitoring, diabetes knowledge, and quality of life.

This study tests a new medicine called SHR-3167 in adults with type 2 diabetes whose blood sugar is not well managed by current pills. About 90 people will receive different doses to see how safe it is and how well it controls blood sugar. The main goal is to check for low blood …

This study tests two types of exercise programs—Modified Otago Exercises and Dynamic Neuromuscular Stabilization Exercises—in 36 older adults with type 2 diabetes and nerve damage in their feet. The goal is to see which program better improves balance and the ability to perform d…

This study tests an 8-week program that sends encouraging messages to help adults with type 2 diabetes become more active and feel better. About 20 participants will use their smartphones to receive these messages. The goal is to see if the program is easy to use and helpful.

This study tests whether a wearable device that vibrates the calf can help improve blood sugar control in adults with type-2 diabetes. About 305 participants in Saudi Arabia will use the device at home for 12 weeks while seated. The goal is to see if this simple, low-effort activ…

This study is testing a new, noninvasive device called the Argus CGM that uses light and AI to estimate blood sugar levels without needles or skin punctures. Up to 100 adults with type 1 diabetes, type 2 diabetes, or prediabetes will wear the device for 15 days while researchers …

This study will test whether a mobile app called Fabla-diabetesMM, which lets people record audio diaries, is easy and helpful for older adults with type 1 or 2 diabetes who also have other health conditions. Thirty participants will use the app and share their thoughts through s…

This study looks at 118 adults of African or Indian descent in the French West Indies who have a rare form of diabetes that is not caused by the immune system. Researchers want to find genetic changes that may explain why these patients develop severe symptoms like ketoacidosis. …

This study looks for early signs of artery hardening in people with both type 2 diabetes and chronic kidney disease. Using a safe neck ultrasound, researchers will check how common these hidden changes are and how they relate to kidney function and blood sugar. The goal is to hel…

This study looks at the gut bacteria of 270 adults in New Caledonia to understand how they relate to obesity and type 2 diabetes. Participants include healthy people, those with obesity, and those with both obesity and diabetes. Researchers will analyze stool samples to find link…

This study looks at whether using a continuous glucose monitor and a Fitbit activity tracker can help people aged 55 and older with type 2 diabetes sit less and control their blood sugar better. Researchers will track how often participants respond to the Fitbit's 'stand' prompts…

This study follows 2,800 Chinese adults aged 18–60 who are overweight or obese, with or without type 2 diabetes, for five years. Researchers will use a digital health platform and AI to track how their metabolic health changes over time, including transitions to diabetes or compl…

This study is a registry that collects long-term safety information from people with type 2 diabetes who have already been treated with the Endogenex System. Researchers will track device- and procedure-related side effects over time. About 500 participants will provide their med…

This study will test a new screening program to find 50-year-olds in Italy who are at risk for type 2 diabetes and heart disease but haven't been diagnosed yet. About 3,000 people will be invited for a check-up using simple questionnaires. Based on their risk scores, they'll get …